Protein

MCA_01638_1

Length
217 amino acids

Gene name: GSP1

Description: GTP-binding nuclear protein GSP1/Ran

Browser: contigA:5042527-5043673+

RNA-seq: read pairs 24302, FPKM 1377.4, percentile rank 97.2% (100% = highest expression)

Protein function

Annotation:GSP1GTP-binding nuclear protein GSP1/Ran
KEGG:K07936RAN GTP-binding nuclear protein Ran
EGGNOG:0PFRIGSP1GTP-binding nuclear protein
SGD closest match:S000005711GSP2GTP-binding nuclear protein GSP2/CNR2
CGD closest match:CAL0000182095GSP1GTP-binding nuclear protein

Protein alignments

%idAln lengthE-value
A0A0F7RS15_GEOCN94.15%2054e-143GTP-binding nuclear protein OS=Geotrichum candidum GN=BN980_GECA03s08117g PE=3 SV=1
MIA_00586_191.26%2062e-141MIA_00586_1
Q59P43_CANAL91.50%2006e-139GTP-binding nuclear protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GSP1 PE=3 SV=1
A0A060TAG4_BLAAD89.76%2057e-139GTP-binding nuclear protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06776g PE=3 SV=1
A0A1E3PS38_9ASCO90.55%2016e-138GTP-binding nuclear protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_54735 PE=3 SV=1
GSP2_YEAST87.75%2042e-136GTP-binding nuclear protein GSP2/CNR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSP2 PE=1 SV=1
UniRef50_P3283589.95%1991e-124GTP-binding nuclear protein GSP1/CNR1 n=1026 Tax=Eukaryota TaxID=2759 RepID=GSP1_YEAST
GSP1_YARLI81.00%2009e-122GTP-binding nuclear protein GSP1/Ran OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=GSP1 PE=3 SV=1
A0A167DVB4_9ASCO94.02%1174e-78GTP-binding nuclear protein OS=Sugiyamaella lignohabitans GN=GSP2 PE=3 SV=1
A0A1E4THL9_9ASCO87.07%1161e-72GTP-binding nuclear protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31946 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0581
Predicted cleavage: 39

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 180 200 217

Detailed signature matches

  1. Family IPR001806
    Small GTPase superfamily
    1. PF00071 (Ras)
  2. Family IPR002041
    Ran GTPase
    1. PS51418 (RAN)
    2. PR00627 (GTPRANTC4)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.70...
  3. G3DSA:3.40.50...
  4. SM00173 (ras_sub_4)
  5. SM00174 (rho_sub_3)
  6. SM00175 (rab_sub_5)
  7. SM00176 (ran_sub_2)
  8. cd00877 (Ran)

Residue annotation

  1. G1 box cd00877
  2. GAP interaction si...
  3. GEF interaction si...
  4. GTP/Mg2+ binding s...
  5. Co-activator inter...
  6. Switch I region cd...
  7. Exportin interacti...
  8. G2 box cd00877
  9. Importin (transpor...
  10. G3 box cd00877
  11. Switch II region c...
  12. G4 box cd00877
  13. G5 box cd00877

Protein sequence

>MCA_01638_1
MAEQQQQSPTFKLVLVGDGGTGKTTFVKRHLTGEFEKRYIATQGVQVYPLDFHTNFGKITFEVWDTAGQEKFGGLRDGYY
INGQCGIIMFDVTSRITYKNVPNWHRDLVRVCENIPVVLCGNKVDVKERKVKAKAITFHRKKNLQYYDISAKSNYNFEKP
FLWLARKLVGNPSLEFVASPALAPPEVQVDEALMAKYQQEMEQATALPLPDEDDADL

GO term prediction

Biological Process

GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.