Protein

MCA_01599_1

Length
660 amino acids

Browser: contigA:4938874-4940857+

RNA-seq: read pairs 3007, FPKM 56.2, percentile rank 67.9% (100% = highest expression)

Protein function

KEGG:K19030PFKFB4 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
EGGNOG:0PG066-phosphofructo-2-kinase
SGD closest match:S000004337YLR345WPutative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W
CGD closest match:CAL0000179837orf19.3689Bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase

Protein alignments

%idAln lengthE-value
MIA_02692_155.57%6730.0MIA_02692_1
A0A0J9XD44_GEOCN52.63%6650.0Similar to Saccharomyces cerevisiae YLR345W Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metabolism of fructoso-2,6-bisphosphate OS=Geotrichum candidum GN=BN980_GECA11s01154g PE=4 SV=1
A0A060T3R3_BLAAD50.60%5810.0ARAD1C35772p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35772g PE=4 SV=1
UniRef50_A0A0J9XG1650.86%5803e-178Similar to Saccharomyces cerevisiae YLR345W Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metabolism of fructoso-2,6-bisphosphate n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XG16_GEOCN
A0A167DEM9_9ASCO50.43%5831e-179Bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase OS=Sugiyamaella lignohabitans GN=AWJ20_1102 PE=4 SV=1
Q6C8B6_YARLI46.35%6026e-164YALI0D21010p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D21010g PE=4 SV=1
A0A1E3PHS1_9ASCO43.98%5738e-150Bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate 2-phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46774 PE=4 SV=1
A0A1E4TD09_9ASCO46.92%3412e-90Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28237 PE=4 SV=1
A0A1D8PCP7_CANAL41.62%3342e-73Bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3689 PE=4 SV=1
YL345_YEAST38.60%3294e-64Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR345W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0245

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 660

Detailed signature matches

  1. Family IPR029033
    Histidine phosphatase superfamily
    1. G3DSA:3.40.50...
    2. SSF53254 (Phosphogl...)
  2. Family IPR013078
    Histidine phosphatase superfamily, clade-1
    1. PF00300 (His_Phos_1)
  3. Family IPR003094
    Fructose-2,6-bisphosphatase
    1. PR00991 (6PFRUCTKNASE)
  4. Domain IPR013079
    6-phosphofructo-2-kinase
    1. PF01591 (6PF2K)
  5. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PIRSF000709 (6PFK_f...)
  3. mobidb-lite (disord...)

Protein sequence

>MCA_01599_1
MSNLKGNVYESAIESDDEEIPQVSGLAPAAPGPFNRSRGSRGSSGGKHSRTTSTASSADRTMSNSSNPGGGYVMRRRESN
VNVDNIHEQPSINDISPAQLYLTDSGHLFHAGKLCVILVGLPARGKTHHSVALTRYLRWLGVKTHAFHLGDYRRKCLNQM
GPDFVVPDDYFTPTPKLQSTIDFRERVLSNCMTDILTFLNQEGGQVAIYDAVNATAKHRKRLVEEYFKPKNIGVLFVECI
ATDDRLVARNVRDVKLSSPDYQGVDYKDAVRNYLKRIELGIPNYETMGSQADENEQHLSYVKLINGTKQIKLNKAPLGYL
QNRIVFFLMNTHVKSGSYFFARAGQGGLEGAEGKEEEKTPTGKFVELCYRDDTKLSSVGHEYAKKLRDTLLHHLEERRNA
RSGASTLGTSTPTELGPTPNIDSVVSERERPDGTKMAKEGSLTEESIQKRLAQAKLHSEASGTSTPNSLGGGGTATPHTN
KYDAYTTPTPTTSRAWTTNPILTHDHSLAKLVVWSSKRIRTIETGQYFADAGYTTVSRPELTQLNPGAADGLTDEEILKE
YPEEFEAHKENPYHHRYPRAESYHDVAVRLEPLIMEMERFEGNLLIIAHESVLCVLYGYLMACTVNDIPFLKFPKNEIVE
ITPGAYYNSATRIPIPNVDP

GO term prediction

Biological Process

GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.