Protein

MCA_01593_1

Length
634 amino acids

Gene name: POL12

Description: DNA polymerase alpha subunit B

Browser: contigA:4921126-4923082-

RNA-seq: read pairs 472, FPKM 9.2, percentile rank 24.6% (100% = highest expression)

Protein function

Annotation:POL12DNA polymerase alpha subunit B
KEGG:K02321POLA2 DNA polymerase alpha subunit B
EGGNOG:0PHS1POL12Dna polymerase
SGD closest match:S000000131POL12DNA polymerase alpha subunit B
CGD closest match:CAL0000183205orf19.2796DNA polymerase alpha subunit B

Protein alignments

%idAln lengthE-value
MIA_03067_144.75%6571e-174MIA_03067_1
A0A0J9X6S0_GEOCN36.71%6926e-125DNA polymerase alpha subunit B OS=Geotrichum candidum GN=BN980_GECA04s00252g PE=3 SV=1
UniRef50_A0A0J9X6S036.71%6921e-121DNA polymerase alpha subunit B n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6S0_GEOCN
A0A161HLN6_9ASCO35.11%6558e-114DNA polymerase alpha subunit B OS=Sugiyamaella lignohabitans GN=POL12 PE=3 SV=1
A0A1E3PFM5_9ASCO35.03%6287e-110DNA polymerase alpha subunit B OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71291 PE=3 SV=1
A0A060T4I0_BLAAD37.73%4932e-97DNA polymerase alpha subunit B OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40854g PE=3 SV=1
A0A1D8PE62_CANAL36.86%4724e-81DNA polymerase alpha subunit B OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2796 PE=3 SV=1
DPOA2_YEAST34.32%4726e-74DNA polymerase alpha subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POL12 PE=1 SV=1
Q6C5E1_YARLI32.72%4869e-71DNA polymerase alpha subunit B OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E18832g PE=3 SV=1
A0A1E4T9J7_9ASCO34.02%4386e-69Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12693 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2145

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 634

Detailed signature matches

  1. Family IPR016722
    DNA polymerase alpha, subunit B
    1. PIRSF018300 (DNA_po...)
  2. Domain IPR013627
    DNA polymerase alpha, subunit B N-terminal
    1. PF08418 (Pol_alpha_B_N)
  3. Domain IPR007185
    DNA polymerase alpha/epsilon, subunit B
    1. PF04042 (DNA_pol_E_B)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_01593_1
MTSDPKQKRISDFLREKFGDSVADDPVILHKWESLSSLFSLSSEEIHSKWEAHDMAVDNLKVVTASSLGDLQERLSKQLA
LENKRLLKSTPQRSMFQTRNTKMSSPAFLQSLLPASSGKKRPNQQSALTSPTKSVRFQEDDSPTKKQKVSSTPHSARKEI
TESVISVLNDDIPQLDSKLSKPTLRTNVDKSKFNHRIMYEKMSDCAEYLDEQIEAFTRDIQKAYNLTNEDFGNPASVSPN
DIYVVGRILPDAATDLNSQLKSVSIQPSRKNGAGMRIELRFPPNLSTHFFPGQIIAAKGSNASGSYFFVNQLLDLPLLPP
VGSSTQKLKAQYTVENHGGLKIFTAAGPFTGPNDLDFTPLKEMIYLIRTKIKPNVVILFGPFISYDHPLIAKGDFTVYRP
RTRIKMPNATLDEFFKCTISNYLRKIDPSVSIVLIPHVSDTASPHPAFPQPAFNRKLLELPKNVYCQTNPATFSLNEVVI
SACSQDTLFALARTSYKLNNPPNIFQSWMKDMIVQRNMFPVYPGLLEEKTGLSTDHKIVSGSNLDIPYLGLADFNKALPD
VFITPSKLKCPSQTIENVVVINPGVAARKEYATVSIHPYNVEELTEDKQYTTNDVYKRVRVETAKIQVNTISED

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity

Cellular Component

None predicted.