Protein
MCA_01592_1
Length
743 amino acids
Gene name: IST2
Description: anoctamin-10, cortical ER protein involved in ER-plasma membrane tethering
Browser: contigA:4918812-4921044+
RNA-seq: read pairs 2092, FPKM 34.7, percentile rank 56.9% (100% = highest expression)
Protein function
| Annotation: | IST2 | anoctamin-10, cortical ER protein involved in ER-plasma membrane tethering | |
|---|---|---|---|
| KEGG: | K19327 | ANO10 | anoctamin-10 |
| EGGNOG: | 0PINZ | PGUG_03099 | plasma membrane channel protein |
| SGD closest match: | S000000290 | IST2 | Increased sodium tolerance protein 2 |
| CGD closest match: | CAL0000183382 | IST2 | Ist2p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03068_1 | 51.95% | 745 | 0.0 | MIA_03068_1 |
| A0A0J9X5X3_GEOCN | 45.67% | 705 | 0.0 | Similar to Saccharomyces cerevisiae YBR086C IST2 Cortical ER protein involved in ER-plasma membrane tethering OS=Geotrichum candidum GN=BN980_GECA04s00263g PE=4 SV=1 |
| UniRef50_A0A0J9X5X3 | 45.67% | 705 | 0.0 | Similar to Saccharomyces cerevisiae YBR086C IST2 Cortical ER protein involved in ER-plasma membrane tethering n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5X3_GEOCN |
| A0A167EQ86_9ASCO | 38.10% | 756 | 3e-177 | Ist2p OS=Sugiyamaella lignohabitans GN=IST2 PE=4 SV=1 |
| A0A060T3M8_BLAAD | 39.59% | 735 | 5e-168 | ARAD1C40876p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40876g PE=4 SV=1 |
| A0A1E3PG73_9ASCO | 37.62% | 715 | 3e-157 | DUF590-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83772 PE=4 SV=1 |
| Q6CB66_YARLI | 35.26% | 624 | 1e-105 | YALI0C21538p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C21538g PE=4 SV=1 |
| A0A1E4TJS8_9ASCO | 36.33% | 545 | 4e-109 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20971 PE=4 SV=1 |
| A0A1D8PE41_CANAL | 29.77% | 598 | 1e-78 | Ist2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IST2 PE=4 SV=1 |
| IST2_YEAST | 25.75% | 563 | 1e-29 | Increased sodium tolerance protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IST2 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0665
Protein family membership
- Anoctamin (IPR007632)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_01592_1 MAQPIARPQQPEETGISSGASRFSNEKPMAQNTSKTTTQPLTKPSGTSLSELGAEYVIDVAVSKDSKDNKANVDKLLKLL LSSGFFAQVRQGNPGTVFVFVKTSAAQLQSLYVQLQIRDFLHDIRKSIPGEPPSPEELEANLTPAEKLRLIHSFLTYPEY DHGLGITPNHGEWSFVKSIFPLQDTELNKKWIKRLGSKFIIDDNEINWMRDQFGEKVALYFAYLQNYFIWLIAPSIIGIL THYVVGSFSMIFGIVNVLWSILFVANWERKEKILALRWGVKGCSKLESVRTSFVPESYQVDYVTGVKKPSYPFWKRFVKE IASIPLVLGAMFAVFTLQIAALTLETFIVQVYQGPLKFIFKLIPTVVLAAIVPVVVAIYKIVANRVLTFENHETEDSYNL SFNQKIFSVSFWTSTGSLFLTAYLYLPFGHLLIPHLDNVSLQFNTFVGASYADGKTFQINGHRLEQQVIYLMVTGQIINF AVEIVVPWAQRTAFELLDKYTNKAPPVFQDSAEEHEFLKSVRRQANSPVFNASEEYQEMVTQFSFVTVFGVAWSLAPLAS LVNNWFELRGDAFKIFRDTKRPIPAREDTIGPWLTDLKYMTWLGSVVTTSLVLMYGNTYTSFADLTKRGMGLVAISPRVL LASIIAAEHLYFLICKIVNFAFSHYPSKEQLEDRKQEYLIRKRLVEGRLETRSVPVDAALTPVEIVWKNLSNPESQAETA ISATILAANPPPKKTSESREKSD
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.