Protein
MCA_01583_1
Length
663 amino acids
Gene name: MMM1A
Description: Maintenance of mitochondrial morphology protein 1
Browser: contigA:4891340-4893332+
RNA-seq: read pairs 943, FPKM 17.5, percentile rank 37.9% (100% = highest expression)
Protein function
| Annotation: | MMM1A | Maintenance of mitochondrial morphology protein 1 | |
|---|---|---|---|
| KEGG: | K17764 | MMM1 | maintenance of mitochondrial morphology protein 1 |
| EGGNOG: | 0PFB3 | MMM1 | Component of the ERMES MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids (By similarity) |
| SGD closest match: | S000003929 | MMM1 | Maintenance of mitochondrial morphology protein 1 |
| CGD closest match: | CAL0000191719 | MMM1 | Maintenance of mitochondrial morphology protein 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02419_1 | 44.19% | 577 | 5e-120 | MIA_02419_1 |
| A0A161HG52_9ASCO | 40.29% | 273 | 9e-56 | Maintenance of mitochondrial morphology protein 1 OS=Sugiyamaella lignohabitans GN=MMM1 PE=3 SV=1 |
| UniRef50_A0A161HG52 | 40.29% | 273 | 3e-52 | Maintenance of mitochondrial morphology protein 1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A161HG52_9ASCO |
| A0A1E3PMP1_9ASCO | 46.45% | 155 | 1e-43 | Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7960 PE=3 SV=1 |
| A0A0J9XBE9_GEOCN | 41.21% | 182 | 1e-39 | Maintenance of mitochondrial morphology protein 1 OS=Geotrichum candidum GN=MMM1 PE=3 SV=1 |
| MMM11_YARLI | 42.41% | 158 | 3e-35 | Maintenance of mitochondrial morphology protein 1-1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MMM1-1 PE=3 SV=1 |
| A0A060TD74_BLAAD | 49.02% | 153 | 3e-35 | Maintenance of mitochondrial morphology protein 1 OS=Blastobotrys adeninivorans GN=MMM1 PE=3 SV=1 |
| MMM1_CANAL | 37.87% | 169 | 7e-30 | Maintenance of mitochondrial morphology protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MMM1 PE=3 SV=2 |
| A0A1E4TEV3_9ASCO | 34.20% | 193 | 7e-27 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13135 PE=3 SV=1 |
| MMM1_YEAST | 56.10% | 82 | 4e-23 | Maintenance of mitochondrial morphology protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MMM1 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0127
Protein family membership
Domains and repeats
-
Domain
1
100
200
300
400
500
600
663
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
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mobidb-lite (disord...)
Protein sequence
>MCA_01583_1 MFGFWKSAKTSGTSPEPLATEIVKVETVTETLLMVQDATFRQNKQYLLSLANDPNSPTNGLGSNKSPLDKLANDISHNGI LNSEPQSPTSPPSLLLVRTPAPTRYPIIFFPFTFGLIAGQFSVIFVMVLCIRYFIFSGSPQDKRDYQSHIRKQRQAKLLP DQEATCKTILEKTYYDVNSHPPESLDWFTVLVAQGLFQLRDDAKHYDNLLNTISKMLNSDSIPSYIDEIFVTELNVGNDF PTFSNCRIIAKDKEDEELCSDEEIDPSELSRSSSVYSRPHVPPQAIRSSRRRSQSFSTYNKRKKFHSSNEASFVKDIEDD NMELEALVDVDLSDTITLGINTRLLLNFPRPKFAAVPISLTVSIVRFSGTLKISLHKPEPDFDMFTDSDEFDQEHGNAYG RNTSSEHFVDSNTNNMETEVVEPTNPEIIQDPENSYSKLADSVGNPSSPDLDTAFEAYPEEPQKAPSTAKDTSAEQNKNS KNSKKNKSYLTVSFEQGPYLEFDIKSSVGGTSVLKDVPKVADIVENLLRNMFQRYFVYPNEKRIYLPTIWPQPDDDRNNT DANKQKGGSNTSNNSKGNNFKGQHHHAYPESNEGSVIINSLNGQQVASSPNEHETQQQQYASRTHTPRLHPRSCSSVSQL ASNTAIIPSFRNLADTQDDSAII
GO term prediction
Biological Process
GO:0007005 mitochondrion organization
Molecular Function
None predicted.
Cellular Component
GO:0032865 ERMES complex