Protein
MCA_01577_1
Length
863 amino acids
Gene name: CDC4A
Description: Cell division control protein 4; F-box protein required for both the G1/S and G2/M phase transitions; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates
Browser: contigA:4878172-4880764-
RNA-seq: read pairs 1641, FPKM 23.5, percentile rank 45.8% (100% = highest expression)
Protein function
| Annotation: | CDC4A | Cell division control protein 4; F-box protein required for both the G1/S and G2/M phase transitions; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates | |
|---|---|---|---|
| KEGG: | K03361 | CDC4 | F-box and WD-40 domain protein CDC4 |
| EGGNOG: | 0PJB9 | FG05455.1 | F-box and WD repeat-containing protein |
| SGD closest match: | S000001885 | CDC4 | Cell division control protein 4 |
| CGD closest match: | CAL0000200882 | CDC4 | SCF ubiquitin ligase complex subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02805_1 | 66.78% | 605 | 0.0 | MIA_02805_1 |
| A0A0J9XBX9_GEOCN | 73.25% | 501 | 0.0 | Similar to Saccharomyces cerevisiae YFL009W CDC4 F-box protein required for G1/S and G2/M transition OS=Geotrichum candidum GN=BN980_GECA09s03068g PE=4 SV=1 |
| A0A060TAP4_BLAAD | 59.54% | 561 | 0.0 | ARAD1B08404p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08404g PE=4 SV=1 |
| A0A167C056_9ASCO | 61.58% | 531 | 0.0 | SCF ubiquitin ligase complex subunit CDC4 OS=Sugiyamaella lignohabitans GN=CDC4 PE=4 SV=1 |
| UniRef50_A0A167C056 | 61.58% | 531 | 0.0 | SCF ubiquitin ligase complex subunit CDC4 n=6 Tax=saccharomyceta TaxID=716545 RepID=A0A167C056_9ASCO |
| A0A1E3PF52_9ASCO | 61.29% | 496 | 0.0 | WD40 repeat-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8119 PE=4 SV=1 |
| Q6CHE8_YARLI | 58.79% | 512 | 0.0 | YALI0A09658p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A09658g PE=4 SV=1 |
| A0A1E4TKW6_9ASCO | 46.43% | 476 | 4e-151 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11423 PE=4 SV=1 |
| Q5A9A6_CANAL | 30.47% | 535 | 2e-64 | SCF ubiquitin ligase complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC4 PE=4 SV=1 |
| CDC4_YEAST | 27.05% | 573 | 1e-51 | Cell division control protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC4 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4296
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Repeat
-
Repeat
1
100
200
300
400
500
600
700
800
863
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
cd00200 (WD40)
-
mobidb-lite (disord...)
Residue annotation
-
structural tetrad ...
Protein sequence
>MCA_01577_1 MPSSIPSSSPKSVSSSSSSPISPQNSILSPTPTKFSKDPLLRLPKENSLLQPSGSTSSGTGFNNSFHSLPTTMNNGSSIS SSQMRRIPFNSSTSSSSSTSSSSSSSSSSTTNANSLQALRETTPPHSHRSPCAPSSPSTPSNSNFNAYTNNNNPNTSSGF SIDKSSIPNQYNSKSYNNNDLFNENTLKQNGAISNDSYSNESQFLSHNDIAPFEGTLPSTPSSAFFNDSNTSISSQVNGS NYNPFSLNSSNNSNKQPFPLPIDTVFEFIKPHLAHYSDDDKVTLIKNILQLTTRPVLAEIQSIISPLLKRDPFAYFPTEI SLRIISFIDEPKTLARASQVSKRWYQVLSDDLTWKELCKSHHYRRLSAAINNLPPANRSLSVSGAEFIYKNTGSASSNGS NAGSDNPEMYDFTEAQYFPDATRQPIPTSYRSHFKHQYMLNTAWQSGGRLAAKYVINHTGVVTSLLMTGGYIVFALDNSK IFVFREDGRLLRSLFGHVMGVWALTLHGDILVSGGCDRDVRVWNIRTGECLKILRGHQSTVRCLQMASSKIAISGSRDAT VRVWDVEEGKCLHVLTGHTLSVRCIEVKGDICVSGSYDCTAKIWRISDGSLIATLNGHFSQIYSLVFDGERIATGSLDAS IRVWNPKTGELLGTLQGHTSLVSQLQIKGDTLVSGGSDGALRIWDLKEFKCIHRLAAHDNSVTSLQFDEERIVSGGSDGR VRIWDMHTAHHIRDLSSPYESVWRIAFKDEKVAILASRNNQIHFELISFCPPRESVTDPFSKFKSESADKNNVSSSGSKF SMLPTISAEMEDVDPIDSANKTNGDKIHDSNRLNIGTSSNSNSSTTAQSAISTVDTPEPMDLS
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.