MCA_01570_1

Protein

Length

452 amino acids

Gene name: SES1

Description: Serine--tRNA ligase, cytoplasmic

Browser: contigA:4857591-4859017-

RNA-seq: read pairs 9680, FPKM 264.0, percentile rank 90.9% (100% = highest expression)

Protein function

Annotation:		SES1	Serine--tRNA ligase, cytoplasmic
KEGG:	K01875	SARS	seryl-tRNA synthetase [EC:6.1.1.11]
EGGNOG:	0PFEB	SES1	seryl-trna synthetase
SGD closest match:	S000002430	SES1	Serine--tRNA ligase, cytoplasmic
CGD closest match:	CAL0000183348	SES1	Serine--tRNA ligase, cytoplasmic

Protein alignments

	%id	Aln length
MIA_03190_1	86.50%	452	MIA_03190_1
A0A0J9XB24_GEOCN	84.96%	452	Similar to Saccharomyces cerevisiae YDR023W SES1 Cytosolic seryl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA06s03640g PE=4 SV=1
A0A060T9R1_BLAAD	83.37%	451	ARAD1D20658p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20658g PE=4 SV=1
A0A167CT16_9ASCO	81.86%	452	Serine--tRNA ligase SES1 OS=Sugiyamaella lignohabitans GN=SES1 PE=4 SV=1
A0A1E3PLE7_9ASCO	81.96%	449	Serine-tRNA ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24019 PE=4 SV=1
Q6C350_YARLI	78.94%	451	YALI0F02629p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02629g PE=4 SV=1
A0A1E4TCX7_9ASCO	77.88%	452	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_141551 PE=4 SV=1
UniRef50_A3LUE7	77.63%	456	Seryl-tRNA synthetase, cytoplasmic (Serine--tRNA ligase) (SerRS) n=108 Tax=Fungi TaxID=4751 RepID=A3LUE7_PICST
SYSC_CANAL	77.46%	457	Serine--tRNA ligase, cytoplasmic OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SES1 PE=1 SV=1
SYSC_YEAST	76.17%	449	Serine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SES1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1456

Protein family membership

Serine-tRNA ligase, type1 (IPR002317)

Domains and repeats

Domain
1 - 117
tRNA-binding arm (IPR010978)
Serine-tRNA synthetase, type1, N-terminal (IPR015866)
124 - 430
Aminoacyl-tRNA synthetase, class II (IPR006195)
Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (IPR002314)
Serine-tRNA ligase catalytic core domain (IPR033729)

1 50 100 150 200 250 300 350 400 452

Detailed signature matches

IPR002317

Serine-tRNA ligase, type1
1. PR00981 (TRNASYNTHSER)
  
  362 - 378
  
  PRINTS
  PR00981 (TRNASYNTHSER)
  
  275 - 287
  
  PRINTS
  PR00981 (TRNASYNTHSER)
  
  287 - 300
  
  PRINTS
  PR00981 (TRNASYNTHSER)
  
  327 - 340
  
  PRINTS
  PR00981 (TRNASYNTHSER)
  
  344 - 360
  
  PRINTS
  PR00981 (TRNASYNTHSER)
2. TIGR00414
  
  1 - 429
  
  TIGRFAMs
  TIGR00414 (TIGR00414)
3. PIRSF001529 (Ser-tR...)
  
  1 - 438
  
  PIRSF
  PIRSF001529 (Ser-tRNA_ligase)
IPR010978

tRNA-binding arm
1. SSF46589 (tRNA-bind...)
  
  1 - 117
  
  SUPERFAMILY
  SSF46589 (tRNA-binding arm)
IPR015866

Serine-tRNA synthetase, type1, N-terminal
1. PF02403 (Seryl_tRNA_N)
  
  1 - 112
  
  Pfam
  PF02403 (Seryl_tRNA_N)
IPR006195

Aminoacyl-tRNA synthetase, class II
1. PS50862 (AA_TRNA_LI...)
  
  147 - 430
  
  PROSITE profiles
  PS50862 (AA_TRNA_LIGASE_II)
IPR002314

Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
1. PF00587 (tRNA-synt_2b)
  
  226 - 413
  
  Pfam
  PF00587 (tRNA-synt_2b)
IPR033729

Serine-tRNA ligase catalytic core domain
1. cd00770 (SerRS_core)
  
  124 - 429
  
  CDD
  cd00770 (SerRS_core)

no IPR

Unintegrated signatures

G3DSA:1.10.28...

1 - 108

GENE3D
G3DSA:1.10.287.40 (G3DSA:1.10.287.40)
G3DSA:3.30.93...

110 - 452

GENE3D
G3DSA:3.30.930.10 (G3DSA:3.30.930.10)
SSF55681 (Class II ...)

139 - 429

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)

Residue annotation

dimer interface cd...

162R

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

163G

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

164A

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

165K

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

166I

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

167S

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

170R

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

171G

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

172Y

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

173F

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

174L

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

175K

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

176T

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

180F

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

182N

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

184A

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

187N

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

199T

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

200A

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

201L

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

202Q

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

204P

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

205V

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

206M

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

208N

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

226Y

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

227K

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

229M

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

235K

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

244P

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

248Y

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

252E

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

270S

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

291A

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

428Y

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)

429I

dimer interface
162R, 163G, 164A, 165K, 166I, 167S, 170R, 171G, 172Y, 173F, 174L, 175K, 176T, 180F, 182N, 184A, 187N, 199T, 200A, 201L, 202Q, 204P, 205V, 206M, 208N, 226Y, 227K, 229M, 235K, 244P, 248Y, 252E, 270S, 291A, 428Y, 429I
CDD
cd00770 (SerRS_core)
active site cd00770

169H

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

240T

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

242E

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

273R

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

275E

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

281K

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

284W

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

287F

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

289V

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

292F

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

294K

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

296E

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

360E

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

361L

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

362V

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

363S

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

396N

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

398T

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)

404R

active site
169H, 240T, 242E, 273R, 275E, 281K, 284W, 287F, 289V, 292F, 294K, 296E, 360E, 361L, 362V, 363S, 396N, 398T, 404R
CDD
cd00770 (SerRS_core)
motif 1 cd00770

199T

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

200A

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

201L

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

202Q

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

203A

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

204P

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

205V

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)

206M

motif 1
199T, 200A, 201L, 202Q, 203A, 204P, 205V, 206M
CDD
cd00770 (SerRS_core)
motif 2 cd00770

272F

motif 2
272F, 273R, 274R, 275E
CDD
cd00770 (SerRS_core)

273R

motif 2
272F, 273R, 274R, 275E
CDD
cd00770 (SerRS_core)

274R

motif 2
272F, 273R, 274R, 275E
CDD
cd00770 (SerRS_core)

275E

motif 2
272F, 273R, 274R, 275E
CDD
cd00770 (SerRS_core)
motif 3 cd00770

399L

motif 3
399L, 400C, 401A, 404R
CDD
cd00770 (SerRS_core)

400C

motif 3
399L, 400C, 401A, 404R
CDD
cd00770 (SerRS_core)

401A

motif 3
399L, 400C, 401A, 404R
CDD
cd00770 (SerRS_core)

404R

motif 3
399L, 400C, 401A, 404R
CDD
cd00770 (SerRS_core)

Protein sequence

>MCA_01570_1
MLDILQFIKEKGGDPEAIKVSQKARGDSVELVDEIIKDYKDWTTIRFDLDGINKELNKVQKEIGLKFKAKEDASELIKEK
EAIAKKKAEYIVKEQEADKALRAKVNLVGNIVHPSVPVSNDEENNELIRTWVPEGVEVSAEKKAALSHHEVLTRLDGYDP
ERGAKISGHRGYFLKTVGLFLNQALINYGLDFLVKKGYTALQAPVMMNKEVMAKTAQLSQFDEELYKVMDGSDEKYLIAT
SEQPISAYHSGEWFEQPAEQLPKRYAGYSSCFRREAGSHGKDAWGIFRVHAFEKIEQFCLTEPDQSWDEFEKMIGYAEEF
YKSLKIPYRVVAIVSGELNNAAAKKYDLEAWFPFQAEYKELVSCSNCTDYQARNLEIRCGIKKMNETEKKYVHCLNSTLC
ATERALCCILENYQTEDGLKVPEVLRKYIPGEPEFIPYSKELPKNSTSTKRK

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006434 seryl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004828 serine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features