Protein

MCA_01566_1

Length
503 amino acids

Gene name: AIM22

Description: Putative lipoate-protein ligase A

Browser: contigA:4846768-4848280+

RNA-seq: read pairs 874, FPKM 21.4, percentile rank 43.1% (100% = highest expression)

Protein function

Annotation:AIM22Putative lipoate-protein ligase A
KEGG:K03800lplA lipoate---protein ligase [EC:6.3.1.20]
EGGNOG:0PKCKAIM22Lipoate-protein ligase
SGD closest match:S000003582AIM22Putative lipoate-protein ligase A
CGD closest match:CAL0000187056orf19.5566Putative lipoate--protein ligase

Protein alignments

%idAln lengthE-value
MIA_02457_141.89%5491e-131MIA_02457_1
A0A0J9XBG6_GEOCN41.95%4726e-123Similar to Saccharomyces cerevisiae YJL046W AIM22 Putative lipoate-protein ligase OS=Geotrichum candidum GN=BN980_GECA09s00054g PE=4 SV=1
UniRef50_A0A0J9XBG641.95%4721e-119Similar to Saccharomyces cerevisiae YJL046W AIM22 Putative lipoate-protein ligase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBG6_GEOCN
A0A1E3PST9_9ASCO45.27%4552e-118Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8170 PE=4 SV=1
A0A060T3R7_BLAAD41.70%4463e-102ARAD1A18282p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A18282g PE=4 SV=1
Q6CD50_YARLI39.07%4535e-101YALI0C03762p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C03762g PE=4 SV=1
A0A1D8PQ09_CANAL37.71%4726e-85Putative lipoate--protein ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5566 PE=4 SV=1
A0A161HHU4_9ASCO38.93%2805e-56Putative lipoate--protein ligase OS=Sugiyamaella lignohabitans GN=AIM22 PE=4 SV=1
LPLA_YEAST38.41%2894e-48Putative lipoate-protein ligase A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AIM22 PE=3 SV=2
A0A1E4TBS4_9ASCO36.88%3011e-47Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_133781 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9533

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 503

Detailed signature matches

  1. Domain IPR004143
    Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain
    1. PS51733 (BPL_LPL_CA...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.93...
  2. SSF55681 (Class II ...)
  3. cd16443 (LplA)

Residue annotation

  1. active site cd16443
  2. catalytic site cd1...

Protein sequence

>MCA_01566_1
MYYVCRRHSLLSLSTKILGKSTLNRVFYSTWINNDRTTEIINLSNPKEFENHVKAPGPKAFVSAMNDPFVNLALENYIFK
NMPEPQQSSEKEAPNKNTFNNNRLLMYINSACIVIGRNQNPWRECNLQLVNSLGIPVLRRRSGGGTVVHDPGNVNFSVMT
AREDFTRDKHAEMIVDAINQLPSTVTKVLKPTLEDESLKDLNKEALMIEEDSIGGLPGMMSSDSALGSGVVEVPGPQIKL
QVNERHDIVDKETGKKVSGSAYKIERQKAYHHGTMLLNSKLDVLSMLLHKDPEIHGTIEGRGVESVKSPVANLGMDSDVF
IQVVLEAFCKKYAVDKSENTTLEKNTDEFVNPLTAGIDDIDVSSDPFTSADSLSIQKAPVPVVHVKKDMLPEDVLEMARE
LRVWDWIYGQTPDFTHTFSHKFADPALEDVVFKFHVSKGFVKDFEVSEDAHKTIDVSVFDPLKTVIQQQPGKLRYIGSEI
EGYVLHDELGNWLKDMIDGVGYA

GO term prediction

Biological Process

GO:0006464 cellular protein modification process

Molecular Function

None predicted.

Cellular Component

None predicted.