Protein

MCA_01545_1

Length
623 amino acids

Description: protein with Zing finger RING/FYVE/PHD-type domain and ING histone binding domain

Browser: contigA:4767809-4769681-

RNA-seq: read pairs 2039, FPKM 40.4, percentile rank 60.4% (100% = highest expression)

Protein function

Annotation:protein with Zing finger RING/FYVE/PHD-type domain and ING histone binding domain
EGGNOG:0PJWHPGUG_01521PHD finger domain protein
SGD closest match:S000005041PHO23Transcriptional regulatory protein PHO23
CGD closest match:CAL0000188113PHO23Chromatin modification-related protein

Protein alignments

%idAln lengthE-value
MIA_04398_181.29%1711e-80MIA_04398_1
A0A0J9YH87_GEOCN63.98%1611e-61Chromatin modification-related protein OS=Geotrichum candidum GN=BN980_GECA01s00791g PE=3 SV=1
UniRef50_A0A0J9YH8763.98%1612e-58Chromatin modification-related protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9YH87_GEOCN
A0A1E3PK40_9ASCO50.30%1671e-41Chromatin modification-related protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_12552 PE=3 SV=1
A0A060T6X1_BLAAD46.11%1672e-35Chromatin modification-related protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22902g PE=3 SV=1
Q6C6K6_YARLI48.21%1685e-31Chromatin modification-related protein OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E08822g PE=3 SV=1
A0A1D8PIP3_CANAL41.83%1533e-29Chromatin modification-related protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PHO23 PE=3 SV=1
A0A167EDG5_9ASCO50.47%1074e-24Chromatin modification-related protein OS=Sugiyamaella lignohabitans GN=PHO23 PE=3 SV=1
PHO23_YEAST75.00%522e-24Transcriptional regulatory protein PHO23 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHO23 PE=1 SV=1
A0A1E4TEK0_9ASCO59.65%571e-21Chromatin modification-related protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147910 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3050
Predicted cleavage: 19

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 623

Detailed signature matches

  1. Domain IPR024610
    Inhibitor of growth protein, N-terminal histone-binding
    1. PF12998 (ING)
    2. SM01408 (ING_2)
  2. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  3. Domain IPR011011
    Zinc finger, FYVE/PHD-type
    1. SSF57903 (FYVE/PHD ...)
  4. Domain IPR001965
    Zinc finger, PHD-type
    1. SM00249 (PHD_3)
  5. Domain IPR019787
    Zinc finger, PHD-finger
    1. PS50016 (ZF_PHD_2)
  6. SITE IPR019786
    Zinc finger, PHD-type, conserved site
    1. PS01359 (ZF_PHD_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd15505 (PHD_ING)
  3. mobidb-lite (disord...)

Residue annotation

  1. H3K4me3 binding si...
  2. Zn binding site cd...

Protein sequence

>MCA_01545_1
MVDVSNSTSTRRSSNGRSRSSKKDQLEKVQQKDIVMVNRKEMASSEEPSQDSPDSQDSSDGTYCVGITDMADALEALPME
LIRHFTLLREIDAKCVFTTPELTRLIKYFLALPLPARELEEAAERAGGPNKISIQVQTQIANLASEREEVLRKIRHLIRE
LMPCLEEKMHVAGVAADAIAKHVARLDYDFNELIVGNNEIPHEVRYGPEIHPAYLPIITAAEQKQAHSTRSEARREAVAA
RKAVAAAAAAAQAVAVVNGNIASGGNGGGSGRNTPRAEESKSTRTGKSTQGSSTTKRRKNASGAGSSANGPSGRNTNNSH
STNHGAELTTGPNGSKGSSSRKDDSNSRKRNNSSVTNSEASSGSKRQKHSGTSGSAASASSGNKQIGSNDSTKNLNEAGN
TSATNAYTEKSKSLDSEVGEDSKSHRKTTASNSSSSKKKVSGSSSNASSNSSSNSKSKKRTSATSGSSSSKPKSKRQDAS
GEYDDEDEDVDMPDSYDSKSGRGQDKSFNVNSSNSTANNDEQVYCYCHQGSYGEMVACDGPHCKNEWFHLPCIGLNTLPK
GKWYCRDCKKELARQKRYNNDGESNNGRNRSGSKHSEDKSHQDSSSSKVKSEISQQASEADLE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.