Protein

MCA_01523_1

Length
838 amino acids

Gene name: MCM7

Description: DNA replication licensing factor MCM7; Component of the Mcm2-7 hexameric helicase complex

Browser: contigA:4723031-4725548-

RNA-seq: read pairs 1159, FPKM 17.1, percentile rank 37.1% (100% = highest expression)

Protein function

Annotation:MCM7DNA replication licensing factor MCM7; Component of the Mcm2-7 hexameric helicase complex
KEGG:K02210MCM7 DNA replication licensing factor MCM7 [EC:3.6.4.12]
EGGNOG:0PGHKMCM7dna replication licensing factor
SGD closest match:S000000406MCM7DNA replication licensing factor MCM7
CGD closest match:CAL0000195352CDC47DNA helicase

Protein alignments

%idAln lengthE-value
MIA_04197_163.73%8520.0MIA_04197_1
A0A0J9XJQ1_GEOCN59.72%8490.0DNA helicase OS=Geotrichum candidum GN=BN980_GECA23s00549g PE=3 SV=1
A0A167DTZ9_9ASCO57.09%8390.0DNA helicase OS=Sugiyamaella lignohabitans GN=MCM7 PE=3 SV=1
A0A1E3PN32_9ASCO56.57%8520.0DNA helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50637 PE=3 SV=1
A0A060T1E7_BLAAD52.68%8410.0DNA helicase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C19822g PE=3 SV=1
A0A1D8PIE7_CANAL50.95%8420.0DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC47 PE=3 SV=1
Q6CE42_YARLI52.33%8370.0DNA helicase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18722g PE=3 SV=1
A0A1E4TFV5_9ASCO51.31%8400.0DNA helicase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_109001 PE=3 SV=1
UniRef50_G8BJ4849.82%8530.0DNA helicase n=151 Tax=Eukaryota TaxID=2759 RepID=G8BJ48_CANPC
MCM7_YEAST48.55%8610.0DNA replication licensing factor MCM7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCM7 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0243

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 838

Detailed signature matches

  1. Family IPR031327
    Mini-chromosome maintenance protein
    1. SM00350 (mcm)
  2. Family IPR008047
    Mini-chromosome maintenance complex protein 4
    1. PR01660 (MCMPROTEIN4)
  3. Domain IPR027925
    MCM N-terminal domain
    1. PF14551 (MCM_N)
  4. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  5. Domain IPR033762
    MCM OB domain
    1. PF17207 (MCM_OB)
  6. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  7. Domain IPR001208
    MCM domain
    1. PS50051 (MCM_2)
    2. PR01657 (MCMFAMILY)
    3. PF00493 (MCM)
  8. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  9. SITE IPR018525
    Mini-chromosome maintenance, conserved site
    1. PS00847 (MCM_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.8.300
  2. G3DSA:2.40.50...
  3. G3DSA:3.30.16...
  4. G3DSA:3.40.50...

Protein sequence

>MCA_01523_1
MNSVLPSVKINVNYEEMKTSFKGFLREFKQALEAPTEDTDMDTSSSVKYMNLLQKVANRQEDTVIIELDDVQAYFRQLEV
ENGFSQNSSSRGGFLGTDSNSISNFVKEVTKNTTHYLELFSQAVDEVMPEPTIDLDYNDSVLDTILHQRRQLNERVRQSN
QPLDVNGRENIYGNLPNTGSNSNDHETFPSALTRRYSLYIKPAINTFNRLPTHIAAAEETALGSKPIAVRDVKAHLIGHL
VTVRGIVTRVSDVKPSVQVNAYACDECGSENFQPVTSKQFMPLLECRSPQCLQNNSRGKLFMVTRSSKFVPFQEARIQEL
ASQVPIGHIPRSLTVQLKGSVVRTLSPGDVVDISGIFTPTPTTSGWRPAGGNTLLTDTYVDAQLISQKKKQYDSLELTLE
EQTIIDRLHSDPAIYDRLAQSIAPEIYGMEDVKKALLLALVGGVTKEMGDGMRIRGDINICLMGDPGVAKSQLLKYISRM
TPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGVCCIDEFDKMDDTDRTAIHEVMEQQTISIAKAGISTT
LNARTSIFAAANPLYGKYNPRLSPVENINLPAALLSRFDLVFLLLDTPNRESDERLAHHVAYVHMTGHSPNAPDNEEEAQ
QAPYDPFSNAPIPPAIINRYISHARQFRPTVPKDVADHVVAAYVKMRQAHHRDQDTQRQLSHITPRTFLGIMRIAQAHAR
LRFSSTVAFEDVEESLRLLDVCKASVSDPQGINSTGNNQTSSFVDSDSSIQSRIYRIIRDLAYGDGAELASSLDMESIQN
RVFAKGYTSDQLNMTLAEYADLQLWQVVQNGARLEFIS

GO term prediction

Biological Process

GO:0006260 DNA replication
GO:0006270 DNA replication initiation

Molecular Function

GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding

Cellular Component

GO:0042555 MCM complex