Protein
MCA_01496_1
Length
713 amino acids
Browser: contigA:4631426-4633568+
RNA-seq: read pairs 2924, FPKM 50.6, percentile rank 65.6% (100% = highest expression)
Protein function
| EGGNOG: | 0PHN1 | PGUG_04532 | Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm) |
|---|---|---|---|
| SGD closest match: | S000004762 | NUP53 | Nucleoporin NUP53 |
| CGD closest match: | CAL0000189064 | orf19.5040 | FG-nucleoporin |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_06271_1 | 36.11% | 565 | 1e-72 | MIA_06271_1 |
| A0A0J9XFH7_GEOCN | 42.07% | 454 | 3e-69 | Similar to Saccharomyces cerevisiae YMR153W NUP53 FG-nucleoporin component of central core of nuclear pore complex (NPC) OS=Geotrichum candidum GN=BN980_GECA14s01847g PE=4 SV=1 |
| UniRef50_A0A0J9XFH7 | 42.07% | 454 | 6e-66 | Similar to Saccharomyces cerevisiae YMR153W NUP53 FG-nucleoporin component of central core of nuclear pore complex (NPC) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XFH7_GEOCN |
| A0A1E3PI14_9ASCO | 31.26% | 467 | 4e-45 | MPPN-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83151 PE=4 SV=1 |
| Q6C9R5_YARLI | 30.12% | 498 | 5e-40 | YALI0D08954p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D08954g PE=4 SV=1 |
| A0A167D8R7_9ASCO | 30.32% | 310 | 2e-32 | FG-nucleoporin ASM4 OS=Sugiyamaella lignohabitans GN=ASM4 PE=4 SV=1 |
| A0A060SX63_BLAAD | 34.51% | 284 | 2e-26 | ARAD1A02046p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02046g PE=4 SV=1 |
| NUP53_YEAST | 32.30% | 161 | 6e-17 | Nucleoporin NUP53 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP53 PE=1 SV=1 |
| A0A1D8PLY0_CANAL | 28.57% | 203 | 2e-14 | FG-nucleoporin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5040 PE=4 SV=1 |
| A0A1E4TDQ4_9ASCO | 27.98% | 193 | 7e-12 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_43604 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0436
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Repeat
1
100
200
300
400
500
600
713
Detailed signature matches
no IPR
Unintegrated signatures
-
cd12721 (RRM_Nup53p...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_01496_1 MNINTNTSSGGGLFGNTSSQSKPLFGSNTNNTLFGNNTTNNSSTNSSFGFGNNNNTNTSGGLFGNNNTNNKPTGLFGNSS NNNSTSGTLFGNASNNNTSSGSLFGNNNNNSSLFGNNSNNANSSFSLNNNNQTNSLFNSSNTSGGGLFSNSSNQQPISQQ QDPNSQSLFGMRSSFSYSSDTDTIHKLAEENLRRSTNNLNSTFQTSQNSLSLSNNGAGFNSTVSSQPQSLYNSPQQIGNA SFSGTASFGNTNQRTSNGLRHSQSSIVLGSGASNASPYRRRSNVPGWAQERRYVPNQTSSLRHVSSFNKTERTTSTTTPG HRKSSTSPSQSPSNSFGGSFSGIPKTSSHTKKKTFIQEDPPPTRSIYDLESSNLDLIKTDTPSDTAADNENALRRPSSTP SDKKGNEPSSAYNRYAGSSIIIFGFPPSLAPEVIAHFANFGTILENVDSTSRIFNRTPSKGGNSHSAPILTGKNWMKITY DNPASASRALQENGFLLHDLYYIGCMPLTAQKLKEFENSSQASMNAAELSVDGMDTSYSNNNFFNGENSLLNSTIPEEPG AEVRMLDSQPANTEHDFNNSQSSLIAGTKKLLNIASNTILSPHNAENNDEANGNQAINGKTLPRTVSLPVLAGSKRAAIK DGRHIFNSPAKQARYPSTPAIFKQNENRHANGYASRNGAVSGDESKKLQNNKPGWMSWTSKKAQEFVFGWDEV
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
Cellular Component
None predicted.