Protein

MCA_01449_1

Length
1,043 amino acids

Gene name: IKS1

Description: Probable serine/threonine-protein kinase Iks1

Browser: contigA:4487823-4491156-

RNA-seq: read pairs 1625, FPKM 19.2, percentile rank 40.4% (100% = highest expression)

Protein function

Annotation:IKS1Probable serine/threonine-protein kinase Iks1
EGGNOG:0PF9WIKS1IKS protein kinase
SGD closest match:S000003593IKS1Probable serine/threonine-protein kinase IKS1
CGD closest match:CAL0000176582orf19.428Protein kinase

Protein alignments

%idAln lengthE-value
MIA_05026_164.84%3649e-146MIA_05026_1
A0A1E3PF94_9ASCO50.12%4152e-105Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84098 PE=4 SV=1
UniRef50_A0A1E3PF9450.12%4156e-102Kinase-like protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PF94_9ASCO
A0A060TC74_BLAAD54.69%3734e-104ARAD1D33924p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D33924g PE=4 SV=1
A0A167F039_9ASCO48.16%4074e-97Protein kinase IKS1 OS=Sugiyamaella lignohabitans GN=IKS1 PE=4 SV=1
A0A0J9X766_GEOCN51.21%3732e-95Similar to Saccharomyces cerevisiae YJL057C IKS1 Putative serine/threonine kinase OS=Geotrichum candidum GN=BN980_GECA04s07072g PE=4 SV=1
Q6C078_YARLI48.12%3723e-94YALI0F27159p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27159g PE=4 SV=1
A0A1E4TG35_9ASCO39.84%3743e-73Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44285 PE=4 SV=1
IKS1_YEAST33.41%4348e-55Probable serine/threonine-protein kinase IKS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IKS1 PE=1 SV=1
A0A1D8PDJ5_CANAL37.75%3473e-45Protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.428 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1970

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 1043

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd00180 (PKc)
  8. mobidb-lite (disord...)

Residue annotation

  1. active site cd00180
  2. ATP binding site c...
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MCA_01449_1
MSLVPVNSHPSWVIVLKDSSRKSLVLYNQISHELALINDPGEFLKYDNRLVSYDPSSVSSNSITTSSNQTLNLFSSQQVL
PSDSLISPVHRNATQIFPNGNQNLSLQPGTHNLNPLHHHAYICQECGAILSDPNRVHNNSNGSHNSNNISTSPEAQMSTE
LTSRMRLLPPNALEAPVVRDANYFKLLEGFTPIHPGSNSASTSTTHTTNGNETDTNSSTNNSEEPNPPGSGFQNYYSISE
NAISQGYFDKFFKLKRKLGQGSRGAVYLVEHVLDGYSLGLFALKKVPVGDDHKWLQKVLEEVHLLRLLSHPNLVSYNHMW
LENSHISRFAPVVPCAFILQEYCDGGTLEDYVNNLQAEVIQAHSIGSNAGIKAKRRRERFRRQSESRSTSSVSPEDILKK
AYLTPEEVLTFARDVFAGVSHLHQAQVIHRDLKPSNCLLLTSGKHRMSHGNASHHKSEGSSRTLPTVLVSDFGEGQLEGI
LRTGTGTTGTLEYCAPELITPGKDGQFVQFSKKTDMFSLGMILHYLCFSRLPYSPRLVDGVDAESLNKLHHEVIQFAGFD
INNIEPRSDLPTEIYSLLARLLSTNPQERPSAKESLETIDRLLQDYRLQKFNSKNDLHGSTPISQYNDTSRTRPIAAVLD
SKKTASDSSSLSSGEKSTEESSSEEEAADLHRHAQIRLISDSSIEDAKQVQNTSAIVKRTFRPLELTDGTSDADFDSSVE
QEKNNNLLTSSYRNTQPPQNNNIIGYSTPTRSSSSVQPFSLSPEALRDQMLDEVETIPNKIKLNGSKNKKKRDIFTPHSR
NNWIQRVTKKGRSSYGNNISNYKKRWMMLISIKTVLFLTKLYMLSSHSPNDTDTFQSISKENSQLESSGFDSTNVPNEKG
FVDQVLPEQDHGSFDEEEYLDSLLHPYDNNNPQQVQRKDNNEGNTPHTIKDGNIFTTVATEISNIIFTVWQTVGDIFSLV
MAWLWTVTESLGVKKFLSVPGELGGTGLVTRIGNQIHSIMETLLSSQNLQNLIILLMGVELPITNIKMIIGFFILHIILV
KNI

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.