Protein

MCA_01448_1

Length
445 amino acids

Gene name: AAT2

Description: Aspartate aminotransferase, cytoplasmic

Browser: contigA:4484131-4485541-

RNA-seq: read pairs 5651, FPKM 156.6, percentile rank 85.3% (100% = highest expression)

Protein function

Annotation:AAT2Aspartate aminotransferase, cytoplasmic
KEGG:K14454GOT1 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
EGGNOG:0PGESAAT2aspartate Aminotransferase
SGD closest match:S000004017AAT2Aspartate aminotransferase, cytoplasmic
CGD closest match:CAL0000174616AAT21Aspartate aminotransferase

Protein alignments

%idAln lengthE-value
MIA_04381_179.51%4490.0MIA_04381_1
A0A0J9X6V3_GEOCN70.70%4130.0Aspartate aminotransferase OS=Geotrichum candidum GN=BN980_GECA04s04949g PE=4 SV=1
A0A060T3Z1_BLAAD68.40%4050.0Aspartate aminotransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C44198g PE=4 SV=1
Q6BZZ9_YARLI63.06%4250.0Aspartate aminotransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F29337g PE=4 SV=1
UniRef50_Q6BZZ963.06%4250.0Aspartate aminotransferase n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6BZZ9_YARLI
A0A1E4T9K3_9ASCO58.29%4100.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_146191 PE=4 SV=1
A0A1E3PJS5_9ASCO55.89%3998e-172PLP-dependent transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50955 PE=4 SV=1
AATC_YEAST51.81%4156e-156Aspartate aminotransferase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AAT2 PE=1 SV=3
Q59N40_CANAL51.58%4112e-151Aspartate aminotransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AAT21 PE=4 SV=1
A0A167EQL1_9ASCO48.17%4099e-136Aspartate aminotransferase OS=Sugiyamaella lignohabitans GN=AAT2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0768
Predicted cleavage: 15

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 445

Detailed signature matches

  1. Family IPR000796
    Aspartate/other aminotransferase
    1. PR00799 (TRANSAMINASE)
  2. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
  3. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  4. Domain IPR004839
    Aminotransferase, class I/classII
    1. PF00155 (Aminotran_1_2)
  5. SITE IPR004838
    Aminotransferases, class-I, pyridoxal-phosphate-binding site
    1. PS00105 (AA_TRANSFE...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00609 (AAT_like)
  2. mobidb-lite (disord...)

Residue annotation

  1. pyridoxal 5'-phosp...
  2. homodimer interfac...
  3. catalytic residue ...

Protein sequence

>MCA_01448_1
MKTLSPQPFPQSRLPSDYSSSNNSTMSANLSQQSVSTSFKVETAPTDPLFGLMARCKADTFPQKVDLGVGAYRDNEGKPW
ILPVVRKVDALISSDPTLNHEYLPIAGMPSLTSGAARLILGSNCSAISQNRVASIQTISGTGSNHLAGLFLSRFPPAGFN
PSKDSNGVIYVSNPTWANHFSIFKNVGLTVKTYPYFKAESLTLDFEGLIDTLSHANKGEIVLLHACAHNPTGIDPTHEQW
AKIADVIIERGLFPFFDCAYQGFASGDLDNDAWAVRHFAERGIEFLVCQSFAKNFGLYGERVGALHVIAADSSTRDAIYS
QLCLLQRSEISNPPAYGGRIVSRILNNPDLFAEWQRDLNTMSSRIIDMRHALRSELVRLRTPGTWDHIVTQIGMFSFTGL
TPEQVDRMVDEFHVYMTRNGRISMAGLNENNVAYVAKAIDAVVRG

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process
GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.