Protein

MCA_01409_1

Length
883 amino acids


Description: protein with Zn(2)C6 fungal-type DNA-binding domain

Browser: contigA:4386564-4389216+

RNA-seq: read pairs 235, FPKM 3.3, percentile rank 14.3% (100% = highest expression)

Protein function

Annotation:protein with Zn(2)C6 fungal-type DNA-binding domain
EGGNOG:0PKVVFG03226.1Fungal Zn(2)-Cys(6) binuclear cluster domain
SGD closest match:S000002441LYS14Lysine biosynthesis regulatory protein LYS14
CGD closest match:CAL0000199985ZCF2Zcf2p

Protein alignments

%idAln lengthE-value
MIA_02464_149.38%8040.0MIA_02464_1
A0A0J9XJQ9_GEOCN48.05%5892e-172Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA23s00670g PE=4 SV=1
UniRef50_A0A0J9XJQ948.05%5894e-169Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJQ9_GEOCN
A0A1D8PDI4_CANAL28.57%4484e-49Zcf2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ZCF2 PE=4 SV=1
A0A1E3PNT3_9ASCO31.93%1192e-13Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49529 PE=4 SV=1
A0A1E4TJN1_9ASCO24.46%2781e-10Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30246 PE=4 SV=1
A0A060T0H4_BLAAD43.04%791e-09ARAD1C16390p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C16390g PE=4 SV=1
A0A167DFN4_9ASCO44.44%546e-09Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1142 PE=4 SV=1
LYS14_YEAST33.86%1279e-09Lysine biosynthesis regulatory protein LYS14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS14 PE=1 SV=2
Q6CBH8_YARLI38.16%763e-08YALI0C18645p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C18645g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0266

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 883

Detailed signature matches

    1. PF00172 (Zn_clus)
    2. PS00463 (ZN2_CY6_FU...)
    3. SM00066 (gal4_2)
    4. SSF57701 (Zn2/Cys6 ...)
    5. PS50048 (ZN2_CY6_FU...)
    6. cd00067 (GAL4)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd12148 (fungal_TF_MHR)
  2. mobidb-lite (disord...)

Residue annotation

  1. DNA binding site c...
  2. Zn2+ binding site ...

Protein sequence

>MCA_01409_1
MDNDKNYTSMWNPKAISSDINSFSDINESSLFSDGFPDNLSQMQNNSPKQMANENTIQPSITSDSVKGLNTSYSRQATSI
SPDSSSTSNKSDAGISSINDITASGVKVAGVKSRKLTSEEKDNQNPAVTSDGKPRKHIRRACLECRKRHIKCDGVLPVCS
KCVASNRECNYVPSHRGGLRIPRNKQQKQQAELAKPNPFASPCMLEDVLTKSAESNASLKKAKTQGQKKSGENDSDEITV
LKPQAVIPDASNFDRFDINPKTLDISPNFSSKSEQLQPLKPIGNEEYITQYLSSNMNSNSQRKGNVEEPAQDENALSDVI
DGVVALSPYSADEVNMSSNSSTGNIHSDSYMTPTNSLLSFPENKASSESSVSYPFDSYVPTPLSNIHSGPDLSLDDILTI
HYTQSHKRHPILPRKDQIQKYLDSIDSPNELVLTLGLLAHITTNVSSQTDISDLKSRISHVFSVLQSAPDDIVKLQATII
LIICSHLSTDNATSSALRKWLFQFLYLKLSAYNLSSPASEGYSSSNDSVPIELFMSSRLNRVDRKLIREGISRVVHEAFF
LEVLFSLIASTPLTQFSLSGVVDTIPISNVPGFAYHARYRTIKVARSILCSLLTVGSGIQFSTEFTRLEALTTTFQGFLS
NNADEQSQFPPLINDLGVVDDGIHQSIVILNFAAIILHFPFSNLYQNRVPSYVECTDTSGPILGPQRLTQSKYRSTVSTR
KCIEAANHIVQIIPDIGSTNIPYRTPLYSCSLAMAMLVHMKAYHWLDQLVPNMSSSGDEEEETRKSEIGLYKEYIKLSSN
ALTTFSQHWILSGKLNTSLCNVMFNVLPELYEHVVETKISQKRKASEALIEKDCWMKQLDVDLDSQNLKLGLDIFDQIFD
LDK

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus