Protein

MCA_01399_1

Length
510 amino acids


Browser: contigA:4365186-4366719+

RNA-seq: read pairs 104727, FPKM 2532.3, percentile rank 98.1% (100% = highest expression)

Protein function

KEGG:K00507SCD stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
EGGNOG:0PFS7PGUG_04871Desaturase
SGD closest match:S000003023OLE1Acyl-CoA desaturase 1
CGD closest match:CAL0000197289OLE1Acyl-CoA desaturase

Protein alignments

%idAln lengthE-value
MIA_02515_183.47%5020.0MIA_02515_1
A0A0J9XG41_GEOCN73.97%5110.0Acyl-CoA desaturase OS=Geotrichum candidum GN=BN980_GECA15s02562g PE=3 SV=1
A0A167CD60_9ASCO77.55%4410.0Acyl-CoA desaturase OS=Sugiyamaella lignohabitans GN=OLE1 PE=3 SV=1
A0A060T7B2_BLAAD76.77%4390.0Acyl-CoA desaturase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D01914g PE=3 SV=1
Q6CCW6_YARLI71.59%4400.0Acyl-CoA desaturase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C05951g PE=3 SV=1
A0A1E4TLF4_9ASCO68.22%4280.0Acyl-CoA desaturase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1182 PE=3 SV=1
A0A1E3PTJ0_9ASCO69.39%4280.0Acyl-CoA desaturase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48902 PE=3 SV=1
UniRef50_A0A178EVP761.96%4390.0Uncharacterized protein n=1 Tax=Trichophyton rubrum TaxID=5551 RepID=A0A178EVP7_TRIRU
Q5A747_CANAL64.99%3970.0Acyl-CoA desaturase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=OLE1 PE=3 SV=1
ACO1_YEAST59.44%3921e-173Acyl-CoA desaturase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OLE1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0260

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 510

Detailed signature matches

    1. PR00075 (FACDDSATRASE)
    2. cd03505 (Delta9-FAD...)
    1. PF00487 (FA_desaturase)
    1. SSF55856 (Cytochrom...)
    2. PS50255 (CYTOCHROME...)
    3. PF00173 (Cyt-b5)
    4. SM01117 (Cyt_b5_2)
    1. PS00476 (FATTY_ACID...)
    1. PS00191 (CYTOCHROME...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)

Residue annotation

  1. Di-iron ligands cd...

Protein sequence

>MCA_01399_1
MASPTTLPLEEVSLEETIAIATGAEARKKYKLKGAFLVHDMNGKDEEEEEAEAEAVAAAAAAAAHKKHHHKHISEQPFTL
SNWHKHINWINTILVVIIPAIGLIMAPFTPLNWKTAALAVAWYAYTGLGITAGYHRLWAHRSYKATLPLRLFLLIAGSGA
AEGSIKWWSNGHRTHHRFTDTDKDPYNARRGFWFSHMGWMVFKQNPKLKARTDISDLIADPLVRFQHKHYMFFLLFASFV
LPTLIAGFGWGDWLGGFVFAGILRNLFVHQSTFCVNSLAHWIGEQPFDDRRSPRDHVLTALVTLGEGYHNFHHEFPSDYR
NALKWYQYDPTKVFIYTCSLLGLAYDLQKFSQNAIEQGLVQQKQKKLDRWRARLNWGVPIEQLPVIEFDEFKEQSKTRAL
VLISGIVHDVTDFIESHPGGKALIKTAIGKDGTAVFNGGVYQHSNAAHNLLATMRVSVIRGGCEVEVWKKAQSEKKDVDL
VSSSNGDKIVRAGLQASRVISSNGVTGRAA

GO term prediction

Biological Process

GO:0006629 lipid metabolic process
GO:0006636 unsaturated fatty acid biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004768 stearoyl-CoA 9-desaturase activity
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0020037 heme binding

Cellular Component

GO:0016021 integral component of membrane