MCA_01384_2

Protein

Length

1,990 amino acids

Gene name: FKS1B

Description: 1,3-beta-D-glucan synthase

Browser: contigA:4321043-4327016-

RNA-seq: read pairs 27637, FPKM 171.5, percentile rank 86.4% (100% = highest expression)

Protein function

Annotation:		FKS1B	1,3-beta-D-glucan synthase
KEGG:	K00706	E2.4.1.34	1,3-beta-glucan synthase [EC:2.4.1.34]
EGGNOG:	0PHH8	FKS1	1,3-beta-glucan synthase
SGD closest match:	S000003264	GSC2	1,3-beta-glucan synthase component GSC2
CGD closest match:	CAL0000176780	GSC1	1,3-beta-glucan synthase

Protein alignments

	%id	Aln length
MIA_03489_1	86.43%	1908	MIA_03489_1
A0A0J9X523_GEOCN	79.98%	1908	Similar to Saccharomyces cerevisiae YLR342W FKS1 Catalytic subunit of 1,3-beta-D-glucan synthase OS=Geotrichum candidum GN=BN980_GECA02s07468g PE=4 SV=1
A0A161HFN5_9ASCO	77.66%	1911	1,3-beta-D-glucan synthase OS=Sugiyamaella lignohabitans GN=FKS1 PE=4 SV=1
A0A060TAL6_BLAAD	76.83%	1882	ARAD1B07546p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07546g PE=4 SV=1
A0A1E3PP30_9ASCO	78.24%	1765	1,3-beta-glucan synthase component GLS2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_21892 PE=4 SV=1
Q6C549_YARLI	73.55%	1822	YALI0E21021p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21021g PE=4 SV=2
A0A1E4TK83_9ASCO	71.37%	1834	Glycosyltransferase family 48 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_759 PE=4 SV=1
FKS2_YEAST	68.74%	1862	1,3-beta-glucan synthase component GSC2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSC2 PE=1 SV=2
UniRef50_P38631	68.43%	1853	1,3-beta-glucan synthase component FKS1 n=735 Tax=Fungi TaxID=4751 RepID=FKS1_YEAST
A0A1D8PCT0_CANAL	68.85%	1830	1,3-beta-glucan synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GSC1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0043

Protein family membership

Glycosyl transferase, family 48 (IPR003440)

Domains and repeats

Domain
400 - 512
1,3-beta-glucan synthase subunit FKS1-like, domain-1 (IPR026899)
939 - 1,353
Nucleotide-diphospho-sugar transferases (IPR029044)

1 200 400 600 800 1000 1200 1400 1600 1800 1990

Detailed signature matches

IPR003440

Glycosyl transferase, family 48
1. PF02364 (Glucan_syn...)
  
  911 - 1,743
  
  Pfam
  PF02364 (Glucan_synthase)
IPR026899

1,3-beta-glucan synthase subunit FKS1-like, domain-1
1. SM01205 (FKS1_dom1_2)
  
  400 - 512
  
  SMART
  SM01205 (FKS1_dom1_2)
2. PF14288 (FKS1_dom1)
  
  402 - 509
  
  Pfam
  PF14288 (FKS1_dom1)
IPR029044

Nucleotide-diphospho-sugar transferases
1. G3DSA:3.90.55...
  
  939 - 1,353
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1,598 - 1,669

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,493 - 1,503

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 545

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

692 - 723

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,801 - 1,913

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,745 - 1,755

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

823 - 1,414

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

614 - 632

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
Coil

342 - 362

COILS
Coil (Coil)
NON_CYTOPLASM... (N...)

1,695 - 1,713

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

747 - 795

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,935 - 1,990

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,776 - 1,780

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

657 - 661

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,524 - 1,569

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,436 - 1,470

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

568 - 593

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

556 - 575

TMHMM
TMhelix (TMhelix)

1,715 - 1,737

TMHMM
TMhelix (TMhelix)

1,913 - 1,935

TMHMM
TMhelix (TMhelix)

1,471 - 1,493

TMHMM
TMhelix (TMhelix)

596 - 618

TMHMM
TMhelix (TMhelix)

1,580 - 1,602

TMHMM
TMhelix (TMhelix)

1,673 - 1,695

TMHMM
TMhelix (TMhelix)

778 - 800

TMHMM
TMhelix (TMhelix)

1,412 - 1,434

TMHMM
TMhelix (TMhelix)

1,781 - 1,800

TMHMM
TMhelix (TMhelix)

724 - 746

TMHMM
TMhelix (TMhelix)

662 - 684

TMHMM
TMhelix (TMhelix)

633 - 655

TMHMM
TMhelix (TMhelix)

1,754 - 1,776

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

1,914 - 1,934

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,714 - 1,744

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

633 - 656

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,504 - 1,523

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,570 - 1,597

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

546 - 567

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

724 - 746

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,670 - 1,694

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,756 - 1,775

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

594 - 613

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

796 - 822

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,471 - 1,492

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,781 - 1,800

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

662 - 691

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,415 - 1,435

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1,971 - 1,990

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 219

MobiDB Lite
mobidb-lite (disorder_prediction)

Protein sequence

>MCA_01384_2
MSNNRPPYDDRYNNGQQDAYYNDDYNNTNPDASSYYGQDNNQHGNYPQQQGGNQYYDDQDPNNPQQQGYYNDDYYYQQNP
NQQQYIDDLNNGYPEDAYAAGPVDPYASSSQQHQMMQQQNPQQARSYNGYQQPGVPSRRLESDEGSETFSDFTMRSDMRG
QDNDYYRGGPGSDPRNNYLPQSGMESLPDGGYGPDAGSRQAYRTTASSQMSYHGNRSSGASTPIYGLDYPNALPSGQRSR
EPYPAWTAENQIPLSKEEIEDIFIDLANKFGFQRDSMRNMYDHFMTLLDSRSSRMTPNQALLTLHADYIGGDNSNYKKWY
FAAQLDLDDEVGFRNMQIGKANRKAKKKAKKANKKNAAAAAAAAEDGINSAAVMEQFEGDNTLEAAEFRWKTHMNQMSQH
ERARQVALYLCCWGEANQVRFTPECLCFIFKCADDYFLSPECQQRTEPIEEGDYLNRVITPIYRYIRDQGYEILDGKFVK
REKDHNKVIGYDDINQLFWYPEGIERIILEDGTRLIDVPAPQRYGKLGEVTWEKVFFKTYRETRSWFHLAVNFNRIWIIH
ITMYWFYVAYNSPTLYTADYIQLQNNQPINHTRWSAVGLGGVVACVIQIAATLSEWAFVPRNWAGAQHLTRRLLFLIILF
AINLAPAIYVFGYIGIAVKSRSALAVAIVQFFIAIATFIFFAIMPLGGLFGSYLKSKNSRRYVASQTFTASFAKLKGNDM
WMSYGLWVCVFTAKMAESYFLLVLSVRDPIRDLSTMTMSRCHGEKWWGDVLCRQQAHVVLGMMYAIDLVLFFLDTYLWYI
ICNTVFSVGRSFYLGISILTPWRNIFSRLPKRIYSKILATTDMEIKYKPKVLISQIWNAIVISMYREHLLAIDHVQKLLY
HQVPSEVEGKRTLRAPTFFVSQDDNQIDSEFFPKNSEAERRISFFAQSLSTPIPEPLPVDNMPTFTVFVPHYSEKILLSL
REIIREDDQFSRVTLLEYLKQLHPVEWDCFVKDTKILAEETSSFSNINGSTDGLDNNDEKDSIKSKIDDLPFYCIGFKSA
APEYTLRTRIWASLRSQTLYRTVSGFMNYSRAIKLLYRVENPEVVQMFGGNTEKLERELERMARRKFKFVVSMQRLTKFK
PEEMENTEFLLRAYPDLQIAYLDEEPPENEGDEPRLFSALIDGHCEIMENGRRRPKFRVQLSGNPILGDGKSDNQNHAII
FYRGEYIQLVDANQDNYLEECLKIRSVLAEFEELNVEHVNPYTPSLPSSTSGKTAETTYPVAILGAREYIFSENVGILGD
VAAGKEQTFGTLFARTLAQIGGKLHYGHPDFLNGIFMTTRGGVSKAQKGLHLNEDIYAGMTALCRGGRIKHCEYYQCGKG
RDLGFGSILNFTTKIGTGMGEQILSREYYYLGTQLPLDRFLSFFYAHPGFHINNLFITLSVQFFMLVLLNIGALANQSII
CLYDRNKPISDPHIPTGCYNLQPVLDWVQRFILSIFIVFFISFIPLIVQELIERGAWRALVRFARHFASLSPFFEVFVCQ
IYSHSLLMDLAFGGARYISTGRGLATARIPFSVLYSRFAGDSIYLGSRSFMMLLFATIAIWQPALLWFYITLAAMLISPF
LYNPHQFAWTDFFIDYRDFIRWLSRGNNKWHRNSWIGYVRLTRSRVTGYKRKVNGDPSEKAAGDIRRTPFFNLFFTEFLL
PAITAAACFIPYTFINAQNGIPEDQAVPVNSTLRIIICTLGPIVINAGALMVLAFISCCAGPLLGMCCKNTSSVMAGIAH
GISVIVFIVFFEVMWLLQSWVWTPALLGMIACINLQRLILKIMTATLLTREFKSDNANRAWWSGKWYSAKFGWMTMTQPL
REFVCKILEQCYFAADFILGHCLLFVQLPMLCIPKIDRWHSMLLFWLRPSRQIRPPIFSLKQTKLRKRMVKKYASLYFGI
LLLFLVLVIAPSVAGKHIDTESISSKLPSFADGLFQPKWVLGVDNNDTGPNAPTTFYTTTPPLTNYSTKP

GO term prediction

Biological Process

GO:0006075 (1->3)-beta-D-glucan biosynthetic process

Molecular Function

GO:0003843 1,3-beta-D-glucan synthase activity

Cellular Component

GO:0000148 1,3-beta-D-glucan synthase complex
GO:0016020 membrane

Filter view on

Entry type

Status

Per-residue features