Protein
MCA_01295_1
Length
825 amino acids
Gene name: VPH1A
Description: V-type proton ATPase subunit a, vacuolar isoform
Browser: contigA:4069521-4072124+
RNA-seq: read pairs 12766, FPKM 191.0, percentile rank 87.6% (100% = highest expression)
Protein function
| Annotation: | VPH1A | V-type proton ATPase subunit a, vacuolar isoform | |
|---|---|---|---|
| KEGG: | K02154 | ATPeV0A | V-type H+-transporting ATPase subunit a |
| EGGNOG: | 0PGDY | VPH1 | Vacuolar ATP synthase |
| SGD closest match: | S000005796 | VPH1 | V-type proton ATPase subunit a, vacuolar isoform |
| CGD closest match: | CAL0000191982 | VPH1 | V-type proton ATPase subunit a |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01868_1 | 76.58% | 824 | 0.0 | MIA_01868_1 |
| A0A0J9X8L0_GEOCN | 70.53% | 828 | 0.0 | V-type proton ATPase subunit a OS=Geotrichum candidum GN=BN980_GECA05s04102g PE=3 SV=1 |
| A0A060TFZ4_BLAAD | 62.85% | 848 | 0.0 | V-type proton ATPase subunit a OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D18832g PE=3 SV=1 |
| A0A1E3PNQ9_9ASCO | 61.96% | 836 | 0.0 | V-type proton ATPase subunit a OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45282 PE=3 SV=1 |
| A0A167CW98_9ASCO | 64.49% | 842 | 0.0 | V-type proton ATPase subunit a OS=Sugiyamaella lignohabitans GN=VPH1 PE=3 SV=1 |
| A0A1E4TL60_9ASCO | 58.51% | 817 | 0.0 | V-type proton ATPase subunit a OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_87061 PE=3 SV=1 |
| Q6BZT1_YARLI | 58.67% | 842 | 0.0 | V-type proton ATPase subunit a OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F31119g PE=3 SV=1 |
| Q59R99_CANAL | 58.69% | 823 | 0.0 | V-type proton ATPase subunit a OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPH1 PE=3 SV=1 |
| UniRef50_Q59R99 | 58.69% | 823 | 0.0 | V-type proton ATPase subunit a n=22 Tax=Saccharomycetales TaxID=4892 RepID=Q59R99_CANAL |
| VPH1_YEAST | 55.98% | 836 | 0.0 | V-type proton ATPase subunit a, vacuolar isoform OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPH1 PE=1 SV=3 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0348
Protein family membership
- V-type ATPase, V0 complex, 116kDa subunit family (IPR002490)
- ATPase, V0 complex, subunit 116kDa, eukaryotic (IPR026028)
Domains and repeats
None predicted.
Detailed signature matches
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PF01496 (V_ATPase_I)
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PIRSF001293 (ATP6V0A1)
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no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_01295_1 MVDHEHEAIFRSAEMSLVQLYIATEIGREVVSSLGELGNIQFRDLNSKVNSFQRSFVKEIRRLDNSERQIRLLKSELEHR SIPSVQVSENISVAPNSSDIDDLVNKLNSLEERVTQLKDSEESLLKREMELKELRYVIRGASTIFAKSDNTTLLSESPSP DTAPLLTTEDDQPDIESGIPASSLANVDFVSGVIAKDKLPVLERILWRALRGNLLLRQVDIDEPIYDPKSGKPVSKSVFV VFTHGSTLLSKVRKISEALDATIYPIDHDDDLRSEGLKEVNSRLEDIKNVVGNTTSAVESELRIVAAKINAWQVVIAKEK AIYSALNLFIYDPRRKCLIAEGWVPKDSISTVKNTLQVITERAGVDIPSIVNELKTNKTPPTYHRVNKFTSAFQAIVDVY AVATYREVNPGLPTVITFPFMFAIMFGDAGHGILLTLAASALVYYETSISKMKRDEIFDMAYSGRYILLLMGIFSIYTGL LYNDMFAQSLTLFKSGWAWPESWKEGETILGHQVGVYAFGLDSAWHGTENNLLFTNSYKMKLSILMGFIHMTYSYMFSLV NHIYFHSMIDIIGNFIPGLLFMQSIFGYLSVCIVYKWTVDWNAIGKTPPGLLNMLISMFLSPGTVEEPLFSHQATLQVIL LLIAFICVPWLLFVKPLYLKRVLDKKAKEHDYQLIGESNGTVAAEPHSVDDDDEEGGHDENFGDIMIHQVIHTIEFCLNC VSHTASYLRLWALSLAHAQLSTVLWSMTLAGAFGATGVFGAFMTVFLFGMWFVLTVCILVIMEGTSAMLHSLRLHWVESM SKFFVGEGHPYTPFSFKTVLSEDNA
GO term prediction
Biological Process
GO:0015991 ATP hydrolysis coupled proton transport
Molecular Function
GO:0015078 hydrogen ion transmembrane transporter activity
Cellular Component
GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain
GO:0033179 proton-transporting V-type ATPase, V0 domain