MCA_01293_1

Protein

Length

1,980 amino acids

Gene name: MOT1

Description: TATA-binding protein-associated factor MOT1

Browser: contigA:4060319-4066400-

RNA-seq: read pairs 3023, FPKM 18.9, percentile rank 39.9% (100% = highest expression)

Protein function

Annotation:		MOT1	TATA-binding protein-associated factor MOT1
KEGG:	K15192	BTAF1	TATA-binding protein-associated factor [EC:3.6.4.-]
EGGNOG:	0PIIR	MOT1	factor mot1
SGD closest match:	S000006003	MOT1	TATA-binding protein-associated factor MOT1
CGD closest match:	CAL0000194262	orf19.4502	DNA-binding ATPase

Protein alignments

	%id	Aln length
MIA_01870_1	75.07%	2010	MIA_01870_1
A0A0J9X8T5_GEOCN	70.12%	1998	Similar to Saccharomyces cerevisiae YPL082C MOT1 Essential abundant protein involved in regulation of transcription OS=Geotrichum candidum GN=BN980_GECA05s04080g PE=4 SV=1
A0A1E3PMY1_9ASCO	62.28%	2081	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_41424 PE=4 SV=1
A0A060TAG3_BLAAD	62.98%	2007	ARAD1D18876p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D18876g PE=4 SV=1
A0A167CWC1_9ASCO	64.63%	1883	Mot1p OS=Sugiyamaella lignohabitans GN=MOT1 PE=4 SV=1
UniRef50_A0A167CWC1	64.63%	1883	Mot1p n=5 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CWC1_9ASCO
Q6BZT4_YARLI	54.52%	2003	YALI0F31053p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F31053g PE=4 SV=1
A0A1D8PH70_CANAL	53.03%	2012	DNA-binding ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4502 PE=4 SV=1
MOT1_YEAST	51.87%	1687	TATA-binding protein-associated factor MOT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MOT1 PE=1 SV=1
A0A1E4TMJ7_9ASCO	47.06%	1651	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30966 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1736

Protein family membership

None predicted.

Domains and repeats

Domain
3 - 1,097
Armadillo-type fold (IPR016024)
Armadillo-like helical (IPR011989)
1,140 - 1,361
Armadillo-type fold (IPR016024)
1,375 - 1,575
Helicase superfamily 1/2, ATP-binding domain (IPR014001)
1,754 - 1,906
Helicase, C-terminal (IPR001650)
Domain
687 - 1,165
Domain of unknown function DUF3535 (IPR022707)
1,343 - 1,614
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,616 - 1,726
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,766 - 1,932
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Domain
1,394 - 1,683
SNF2-related, N-terminal domain (IPR000330)

1 200 400 600 800 1000 1200 1400 1600 1800 1980

Detailed signature matches

IPR016024

Armadillo-type fold
1. SSF48371 (ARM repeat)
  
  1,140 - 1,361
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  367 - 470
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  520 - 711
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1,034 - 1,085
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  4 - 77
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
IPR011989

Armadillo-like helical
1. G3DSA:1.25.10.10
  
  3 - 1,097
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
IPR022707

Domain of unknown function DUF3535
1. PF12054 (DUF3535)
  
  687 - 1,165
  
  Pfam
  PF12054 (DUF3535)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  1,616 - 1,726
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,766 - 1,932
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,343 - 1,614
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR014001

Helicase superfamily 1/2, ATP-binding domain
1. PS51192 (HELICASE_A...)
  
  1,391 - 1,564
  
  PROSITE profiles
  PS51192 (HELICASE_ATP_BIND_1)
2. SM00487 (ultradead3)
  
  1,375 - 1,575
  
  SMART
  SM00487 (ultradead3)
IPR000330

SNF2-related, N-terminal domain
1. PF00176 (SNF2_N)
  
  1,394 - 1,683
  
  Pfam
  PF00176 (SNF2_N)
IPR001650

Helicase, C-terminal
1. PS51194 (HELICASE_CTER)
  
  1,754 - 1,906
  
  PROSITE profiles
  PS51194 (HELICASE_CTER)
2. SM00490 (helicmild6)
  
  1,779 - 1,865
  
  SMART
  SM00490 (helicmild6)
3. PF00271 (Helicase_C)
  
  1,757 - 1,865
  
  Pfam
  PF00271 (Helicase_C)

no IPR

Unintegrated signatures

Coil

988 - 1,008

COILS
Coil (Coil)

1,975 - 1,980

COILS
Coil (Coil)
G3DSA:3.40.50...

1,345 - 1,613

GENE3D
G3DSA:3.40.50.10810 (G3DSA:3.40.50.10810)
G3DSA:3.40.50...

1,740 - 1,903

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
NON_CYTOPLASM... (N...)

25 - 1,980

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 24

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

20 - 24

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

7 - 19

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 6

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
cd00046 (DEXDc)

1,399 - 1,546

CDD
cd00046 (DEXDc)
cd00079 (HELICc)

1,755 - 1,873

CDD
cd00079 (HELICc)
mobidb-lite (disord...)

1,728 - 1,751

MobiDB Lite
mobidb-lite (disorder_prediction)

225 - 301

MobiDB Lite
mobidb-lite (disorder_prediction)

1,924 - 1,951

MobiDB Lite
mobidb-lite (disorder_prediction)

751 - 796

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

1,407G

ATP binding site
1,407G, 1,408L, 1,409G, 1,410K, 1,411T
CDD
cd00046 (DEXDc)

1,408L

ATP binding site
1,407G, 1,408L, 1,409G, 1,410K, 1,411T
CDD
cd00046 (DEXDc)

1,409G

ATP binding site
1,407G, 1,408L, 1,409G, 1,410K, 1,411T
CDD
cd00046 (DEXDc)

1,410K

ATP binding site
1,407G, 1,408L, 1,409G, 1,410K, 1,411T
CDD
cd00046 (DEXDc)

1,411T

ATP binding site
1,407G, 1,408L, 1,409G, 1,410K, 1,411T
CDD
cd00046 (DEXDc)
putative Mg++ bind...

1,515D

putative Mg++ binding site
1,515D, 1,516E, 1,517G, 1,518H
CDD
cd00046 (DEXDc)

1,516E

putative Mg++ binding site
1,515D, 1,516E, 1,517G, 1,518H
CDD
cd00046 (DEXDc)

1,517G

putative Mg++ binding site
1,515D, 1,516E, 1,517G, 1,518H
CDD
cd00046 (DEXDc)

1,518H

putative Mg++ binding site
1,515D, 1,516E, 1,517G, 1,518H
CDD
cd00046 (DEXDc)
nucleotide binding...

1,773Q

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,774L

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,775K

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,776D

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,797R

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,798L

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,827T

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,828H

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)

1,829V

nucleotide binding region
1,773Q, 1,774L, 1,775K, 1,776D, 1,797R, 1,798L, 1,827T, 1,828H, 1,829V
CDD
cd00079 (HELICc)
ATP-binding site c...

1,835N

ATP-binding site
1,835N, 1,856Q, 1,860R, 1,863R
CDD
cd00079 (HELICc)

1,856Q

ATP-binding site
1,835N, 1,856Q, 1,860R, 1,863R
CDD
cd00079 (HELICc)

1,860R

ATP-binding site
1,835N, 1,856Q, 1,860R, 1,863R
CDD
cd00079 (HELICc)

1,863R

ATP-binding site
1,835N, 1,856Q, 1,860R, 1,863R
CDD
cd00079 (HELICc)

Protein sequence

>MCA_01293_1
MSRLDRLVLLLDTGSSAFVRNTAADQLADVQKAHPEDLLNLLGRVFPYLKSKKWDTRISAARALGGIVANAPKWDPNSDD
TTSRIECLDEPQVKKEESDLSDTKIKQEPSDNTTIEIENKNDSLIKTESKALIKAEIEATTEDEKKALENDKSLMELDEE
SLLTFKTLDIKNVMKYGGKLVSSAGKEYDDPTADMNPVERLKKQKLDLKKRLGMGNEYLDDEIFNENDLASTPKTPSSTC
DKPKRPNSRSKQSSTSKSARVTPPETLPPDPVSASNARLRAMARRKAKNGAKQNQNKVRVVDLADSSAARKMEEEGGSNP
TAVKLNAEDQPQWTTTTQGHNDKVVVEHKAPKVSPLLNMSSSAGLVWPFEGLCELLMIDLFDPVWEVRHGAALGLREVIK
VHGAGAGRVIGKSRQDNDERNKCWLEDLSCRLCCVFALDRFGDYVGDQVIAPVRESTAQTLGALLLHLPDSVIKDTFDVL
CKLVLQKDFGSHPMWEACHGGMLGLRYLVSVRNDILFKNTDYFDGLITCVIHGLNESDDDVQAMSAATLIPIANEFVTLR
PNQIPELLDVIWNCLAELKDDLSASIGNVMDLLAKLSEFPQVLEIIKQNAEVDESKSFSMLVPRLSPFLRHSITNVRKSV
LRALKTFLEIDGAGTKEWINDIMFRLIFQNLLVEQNKDVLSLSLELWNSLLDHSVEFNPVKGSFSITKTLMPHVNNLLTL
LMTPIGSARTSYKMDTSLMIKPSGSPISYSRPCNYLENDTNSNGNNNGNGKGSGTEQKNRRKRKNQEPSSPKESSIPVSF
QINIDSAMLNGDVTLIDFSTFLRTRITASKAFGRLLSLWDPSMLQNISFKPYLSSPFSTPRLFSGIVLEEYSKSLTPENA
ENPHHKAYKEFYVEHFNTMLNNENSISMYRDFVPYLKAVRTQCLSLFSVFVESAKLSRHKVPQIAVVVQGEPEAGPDAFS
IETATNIINTTYDKLKRSLSASYRITCGKMLEDALRNLKHSVQEAENAKLCRDISILAAIACAYVSFNSLPKKLNPIIRS
LMDSVKSEEHEQLQERSAESISNLIHMFIDIGKTGASDKIIKNLCSFLCVDTSEVPEFHPNKQFFDKILSLRKEEAKTDP
TDIIAHQLEVQAARIKRLGAYTALVHISKSYGPELFEKLPKLKECMFKALPSPDSETFVIPESINDPESTYGQDIIDSLS
VIRALLPSIDPALYGEFTHILPLIQKILNVKYSVLRYTAAKCFASICKVMPVEGITYLVENILLMVSNALDVYAREGAIE
CIYHLTSTMGSDILPYVVFLIVPVLGRMSDPDQDIRLLATTTFASIIKLVPLESGIPDPPGMSSKLLEGRDREREFISQM
LDVSKVQTFKLPVAIKASLRSYQQEGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDHHLRAEEHAKTGSVETRRL
PSIVICPPTLTGHWMHEFNQYAPFMKCLCYVGPPNVRQKLIPTFNDYDVVITSYDITRNDINLIQPQNWNYCTLDEGHII
RNASSKLTQAVKKLVANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKVFNERFAKPIAASRNSKSSSKEQEAGALAL
EALHKQVLPFLLRRLKEDVLADLPPKIIQDYYCELSDLQKQLYESFAKKQKTEVSGEVESKEGKQHIFQALQYMRKLCNH
PALIMNPKHPQYDSVMTKLSQNHENIRDIQHAPKLLALQELLKSSGIGVDSPPVSTGSSSGRPRSNGNSTTNAQITELQS
AVTSQHRALIFCQLKDMLDIVENDLFKKYMPSVTYMRLDGSKDVRVRHEIVQKFNGDPSIDVLLLTTHVGGLGLNLTGAD
TVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRLITRNTLEEKIMGLQKFKLNIASSVINQQNSGLASMDTDQLLDLFE
TPDTVTEKSNSGDDASKALDETGQIKGKGNNPIGELGELWDEKDYEEEYNLDNFIQNLKV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding
GO:0005524 ATP binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_01293_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component