Protein

MCA_01242_1

Length
1,050 amino acids

Gene name: CDC14

Description: Tyrosine-protein phosphatase CDC14

Browser: contigA:3905054-3908207-

RNA-seq: read pairs 1740, FPKM 20.5, percentile rank 42.1% (100% = highest expression)

Protein function

Annotation:CDC14Tyrosine-protein phosphatase CDC14
KEGG:K06639CDC14 cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
EGGNOG:0PHH0CDC14-phosphatase
SGD closest match:S000001924CDC14Tyrosine-protein phosphatase CDC14
CGD closest match:CAL0000180943CDC14Tyrosine-protein phosphatase CDC14

Protein alignments

%idAln lengthE-value
A0A0J9XID9_GEOCN77.52%4270.0Similar to Saccharomyces cerevisiae YFR028C CDC14 Protein phosphatase required for mitotic exit OS=Geotrichum candidum GN=BN980_GECA19s01341g PE=4 SV=1
MIA_00299_173.50%4340.0MIA_00299_1
A0A060THY7_BLAAD68.54%4260.0ARAD1D35002p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35002g PE=4 SV=1
A0A1E3PER1_9ASCO69.32%4140.0Phosphatases II (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7007 PE=4 SV=1
Q6C5Q7_YARLI64.30%4370.0YALI0E16038p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16038g PE=4 SV=1
UniRef50_Q6C5Q764.30%4370.0YALI0E16038p n=15 Tax=Saccharomycetales TaxID=4892 RepID=Q6C5Q7_YARLI
A0A1E4TIB4_9ASCO59.02%4272e-180Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29909 PE=4 SV=1
CDC14_CANAL56.51%4304e-172Tyrosine-protein phosphatase CDC14 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC14 PE=1 SV=2
CDC14_YEAST54.61%4451e-169Tyrosine-protein phosphatase CDC14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC14 PE=1 SV=2
A0A167FCE8_9ASCO72.17%3272e-167Phosphoprotein phosphatase CDC14 OS=Sugiyamaella lignohabitans GN=CDC14 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3167
Predicted cleavage: 19

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1050

Detailed signature matches

  1. Domain IPR029021
    Protein-tyrosine phosphatase-like
    1. SSF52799 ((Phosphot...)
    2. G3DSA:3.90.19...
  2. Domain IPR029260
    Dual specificity/tyrosine protein phosphatase, N-terminal
    1. PF14671 (DSPn)
  3. Domain IPR000340
    Dual specificity phosphatase, catalytic domain
    1. PF00782 (DSPc)
  4. Domain IPR003595
    Protein-tyrosine phosphatase, catalytic
    1. SM00404 (ptp_7)
  5. Domain IPR000387
    Tyrosine specific protein phosphatases domain
    1. PS50056 (TYR_PHOSPH...)
  6. Domain IPR020422
    Dual specificity protein phosphatase domain
    1. SM00195 (dsp_5)
  7. SITE IPR016130
    Protein-tyrosine phosphatase, active site
    1. PS00383 (TYR_PHOSPH...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_01242_1
MTVSSSSRRRIPLIEFLKNRIYLGAYDSPPEDTDSMVHFTIDDALPYNPFHHDFGPLHIGHLYRFAVTLHEVLGEEKNEG
KAVCLYSRTNPRDRANTACVLCCYMVLIQSWPPHLALAPIAQAEPPFMPFRDAGYAAADFILTIQDVIYGVWKAKEHKLI
DIKTFNLEEYELYERVDQGDFNEIPPHFIAFASPQQQSDYSNDDINGTTYDTELNYPFHQVLNYFSTHDVKLVVRLNSHL
YDKTEFEKRGIKHVDLVFEDGTCPTLEYVQAFLGAVEGVIAEGGKVAVHCKAGLGRTGCLIGAHLIYTYGFTASEVIAYM
RFLRPGMVVGPQQHWLYLHQNEFRDWRHTMCVSKTASEKLAGFCPLVPKTSQNFVQYMVSPESGAVRHALVSQGGRTPSP
KTPERSVLHQVGNTNTALPVPTPGQPRKYSPIHHQSRRVSSSTRRIINRRKSSNNSRHKRNSNVPIGMEDEYEDDGEYDE
FGNRRETIYHDAQRYFSDDELEQQQPIDDNEAKEANDTLNDYEDEADETFNDNSCSPKRHTSYISSSSSPQRNRVLSNSN
SGSLNVNKTRSASGKGLHVAKRTNSAAGHSRSLSSSTMKINRSMHGSPSRSSSAAVVALRTRSASGNTTVEENEEDEMME
DGNNNKILVNKSSERKVSSKRNYGGASISKTTTTTTTTTTTTHITTPSKYRGPVQDDVFANDEDTGMIGEEEQQQDQESQ
RFQPQRVIVGRNAYVPGIYSTNSDDERLYDEHADDYEGNYEDDNMYNDDYDDYEDYENYGSASPNKQRVSSASTSVQRNN
RKTSLTMKRANDLKQNNPRRIVTDSFTQKQLLKQQQQQQHDQQNKILKMRKLRSTSNNSAAAIITNTNNNNSEISSPKKR
VSSSSSSSSSSSSSSVLSINNSTGDENEAQQSTVEETKPSSKHNHSRRTASRSTRSVSSSGSIKVPNSSTAGITKSSPAT
IISSSTVSSSSNNNTISVVKKRKSSGSTSVKSLEAAVIGAVVSSAATINGDNKKEKENEGNEAAAAEEEGNNSTTILRRS
LRISSNSISH

GO term prediction

Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

Molecular Function

GO:0004725 protein tyrosine phosphatase activity
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity

Cellular Component

None predicted.