Protein

MCA_01223_1

Length
342 amino acids

Gene name: BTS1

Description: Geranylgeranyl pyrophosphate synthase

Browser: contigA:3853045-3854587-

RNA-seq: read pairs 558, FPKM 20.1, percentile rank 41.5% (100% = highest expression)

Protein function

Annotation:BTS1Geranylgeranyl pyrophosphate synthase
KEGG:K00804GGPS1 geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]
EGGNOG:0PG5TBTS1geranylgeranyl
SGD closest match:S000005990BTS1Geranylgeranyl pyrophosphate synthase
CGD closest match:CAL0000181440BTS1Farnesyltranstransferase

Protein alignments

%idAln lengthE-value
MIA_00325_165.77%2984e-151MIA_00325_1
A0A0J9X7P9_GEOCN71.48%2844e-149Similar to Saccharomyces cerevisiae YPL069C BTS1 Geranylgeranyl diphosphate synthase OS=Geotrichum candidum GN=BN980_GECA04s05862g PE=3 SV=1
A0A060T379_BLAAD64.39%2786e-135ARAD1C38588p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38588g PE=3 SV=1
A0A1E3PDW9_9ASCO63.93%2804e-133Farnesyltranstransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47946 PE=3 SV=1
UniRef50_D5GN2657.82%2941e-121Uncharacterized protein n=5 Tax=Pezizomycotina TaxID=147538 RepID=D5GN26_TUBMM
Q6C8T9_YARLI58.03%2743e-115YALI0D17050p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17050g PE=3 SV=1
GGPPS_YEAST46.10%2951e-85Geranylgeranyl pyrophosphate synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BTS1 PE=1 SV=1
A0A1E4TJV8_9ASCO45.95%2592e-78Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30300 PE=3 SV=1
A0A1D8PNS6_CANAL42.21%2891e-69Farnesyltranstransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BTS1 PE=3 SV=1
A0A167CVK3_9ASCO24.69%2394e-11Trans-hexaprenyltranstransferase OS=Sugiyamaella lignohabitans GN=COQ1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1565

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 342

Detailed signature matches

  1. Family IPR000092
    Polyprenyl synthetase
    1. PF00348 (polyprenyl...)
  2. Domain IPR008949
    Isoprenoid synthase domain
    1. SSF48576 (Terpenoid...)
    2. G3DSA:1.10.60...
  3. SITE IPR033749
    Polyprenyl synthetase, conserved site
    1. PS00723 (POLYPRENYL...)
    2. PS00444 (POLYPRENYL...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. SFLDG01017 (Polypre...)
  4. SFLDS00005 (Isopren...)
  5. TRANSMEMBRANE (Tran...)
  6. cd00685 (Trans_IPPS_HT)
  7. mobidb-lite (disord...)

Residue annotation

  1. SFLDG01017
  2. substrate binding ...
  3. chain length deter...
  4. aspartate-rich reg...
  5. SFLDS00005
  6. catalytic residues...
  7. substrate-Mg2+ bin...
  8. active site lid re...
  9. aspartate-rich reg...

Protein sequence

>MCA_01223_1
MSDFDSQQCIENCLNCVNRQTFWSDQYQKILLGPYQYLTKVPGKNMRSKLINAFNSVLQVDQSAIKIISEIVGMLHNASL
LIDDVEDNSALRRGYPVAHSIFGTAQTINSSNYIYFLSLQKVIQLNHEQVTEIFTEELINLHRGQGLDLYWRDTLSCPTE
EEYLDMVMNKTGGLYRLAVRLMQELSSVKIWYISNLIPLANIFGIIYQIQDDYLNLQSQSYTDNKGFCEDLTEGKFSFPI
IHSIRSDTNNKEIINILKQKTTDYTLKKYAVDYMRNSTNSFKYTKNVLKCYCDVARKMIYEIQDQINKTSSKTGKNEKEE
GKEERSQVSDLLDILTFMETMS

GO term prediction

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

None predicted.

Cellular Component

None predicted.