Protein

MCA_01199_1

Length
1,542 amino acids


Gene name: TFC3

Description: Transcription factor tau 138 kDa subunit

Browser: contigA:3798906-3803676+

RNA-seq: read pairs 910, FPKM 7.3, percentile rank 21.1% (100% = highest expression)

Protein function

Annotation:TFC3Transcription factor tau 138 kDa subunit
EGGNOG:0PK3NTFC3transcription factor C subunit 3
SGD closest match:S000000001TFC3Transcription factor tau 138 kDa subunit
CGD closest match:CAL0000177979orf19.3833Transcription factor TFIIIC subunit

Protein alignments

%idAln lengthE-value
MIA_00526_144.94%4948e-120MIA_00526_1
A0A0J9XIM6_GEOCN35.28%4964e-83Similar to Saccharomyces cerevisiae YAL001C TFC3 Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC) OS=Geotrichum candidum GN=BN980_GECA21s00978g PE=4 SV=1
UniRef50_A0A0J9XIM635.28%4969e-80Similar to Saccharomyces cerevisiae YAL001C TFC3 Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIM6_GEOCN
A0A1E3PNR4_9ASCO24.41%8111e-51Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49520 PE=4 SV=1
A0A167FDX7_9ASCO27.93%4694e-47Transcription factor TFIIIC subunit TFC3 OS=Sugiyamaella lignohabitans GN=TFC3 PE=4 SV=1
A0A060T035_BLAAD23.05%7811e-46ARAD1C13530p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C13530g PE=4 SV=1
Q6CB35_YARLI30.94%2782e-36YALI0C22231p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C22231g PE=4 SV=1
A0A1E4TK44_9ASCO23.11%5412e-27Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82656 PE=4 SV=1
A0A1D8PM51_CANAL25.10%4865e-25Transcription factor TFIIIC subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3833 PE=4 SV=1
TFC3_YEAST24.84%4592e-21Transcription factor tau 138 kDa subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TFC3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0665

Protein family membership

Domains and repeats

1 200 400 600 800 1000 1200 1400 1542

Detailed signature matches

    1. PF04182 (B-block_TF...)
    1. SSF46785 ("Winged h...)
    1. cd16169 (Tau138_eWH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00090 (HTH_ARSR)
  2. mobidb-lite (disord...)

Residue annotation

  1. putative DNA bindi...
  2. dimerization inter...
  3. putative Zn2+ bind...

Protein sequence

>MCA_01199_1
MTTLSPPEIISFLLEELAYTTEPLSLPGLWSNLEKIVAKNESFYRSIVWGWLKHKKHELVLAYQGKKVPDNILNLSYPQL
LKKYDESKLTLALTDEELFLKLTGVPRSRSDLGEFPFKLLCRIAQSRSEGIISAQLAKDTGQDARSMTGRLNLLIQLGLI
KKYPIIAKGSWTYVSVYKKFTWVNRDKGNITNNKKRATGKDINVDKSLIRRNIMDLLKLSPKGIRLYLDIAEELKVNRRV
LSSFLKKLEKEGYIEQLFIFHQDAPHRKFLCSKFLKDLPANDDPDYDDDESDECDEAEIENKATADGGNDDSLMVSDTSR
PDDIASMQQLSVSVHSNTNQSISDSQSKNSSNIRCYNTVYSLQNQIYQLIQQSGATGMPGSEVLHKLTGKGFTRVVTKEL
ADIAGTLPAKSFAKYVNTPLGNLLTIKGVDFASRVKFYRYFTYVAYSAMNNIPAKDIWGNFFQPEKRFRSLAFMEKERYT
PLPGRLPIRGLAKDIPEASSETQALIPAKKPAHVVETEAKISNSTKKRGRPPKSRKRTVVKKRKVDNPENTIENINEVAE
TASPSEIQEDTSFQLSHSDSISSTLSIAQRAMNQLSLPTNHNSNARQSRLDGFLNSASPPPYNSQINATTTARAEDLMLV
DPLIQSSQTEFLQSDSSEFLNVDSFMHAFPSPNDSATAHSSNLLQVEDTLQEPSNNLKVSETEEHSLIPPPDQEKENAVT
IATELPDSEAQTQSQNQNQEKEQVQETEEQRKVSAEDDDQDAENITLSSDSFSLIQIRRINQAIDLLKSRGGICESGTTF
TKKFNEKYNSINKSDMDRKTSISLINTMVQNGKVRIIDLSDQIQNPQRLIATQLIVLPEISDNDPALVEAKKKLINEAGI
PSKKSTAYEGVKVSNETTFNVVTPKYKMLLELSSKRYRNFFIPKSDKARSAKRLNEADSRLLKITRKPRSKKSVDKPDKP
DKTERHERSQKSSRTKNVPILPKSSDSLSEIQKESTPDSNRVNPVDPIHLLDEDIARKLRRHSSRVTVKSRELNDSLLSK
SRETPSKTCSDNNTPINRRSGIFTHTSFSSINSIDIFVRVVLIIRSFSETKGSQYDWAHITRELNHWFPDATSDQVRRFW
TRVRSKIGGAKALNALMDYWSTLFETAYLNRKIKRMELDNLDIPYLVKYWTKVQPSLYDAHISPELYLNAEQYESDYILE
AEEYKGYEKFDVMFRNRSMVIVADTLGSIAMSTPKTIPPGDSYFEEVDPEVESIKSLVKAIIAAPEAQYDEQKAAALLKK
VSEKDNGTSSLNKAMKSLDSENAIVYVPRDVSKVQPGRNYMFADKFMGVISLRIEPTFFLDATKLRDLLLSSFQENTGYK
ASKSISDGEMLCLLDLVCSSHKNLELEVVDIRKGEHLLGSQSSTKPTNAGNRFVDKSKYEAEIVVKSKVDVSENNFMKLL
HRHVAPPIGEPGQYIWSGIGNGLSFPIFERLVVWILLYMVLRPGTSTDRIYHAIKPVLSKTEVNVLARWLIDSRIVEQFT
GTPNGRQGLRLRHGWYHNIFNF

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.