MCA_01181_1
Gene name: BIO3-4
Description: putative bifunctional dethiobiotin synthetase adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Browser: contigA:3723862-3726861+
RNA-seq: read pairs 48, FPKM 0.7, percentile rank 7.7% (100% = highest expression)
Protein function
| Annotation: | BIO3-4 | putative bifunctional dethiobiotin synthetase adenosylmethionine-8-amino-7-oxononanoate aminotransferase | |
|---|---|---|---|
| KEGG: | K19562 | BIO3-BIO1 | bifunctional dethiobiotin synthetase / adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:6.3.3.3 2.6.1.62] |
| EGGNOG: | 0QDKK | BIODA | bifunctional dethiobiotin synthetase adenosylmethionine-8-amino-7-oxononanoate aminotransferase |
| SGD closest match: | S000005341 | BIO3 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase |
| CGD closest match: | CAL0000178609 | CAALFM_CR01920WA | Adenosylmethionine-8-amino-7-oxononanoate transaminase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_06265_1 | 50.38% | 913 | 0.0 | MIA_06265_1 |
| A0A0J9XKG6_GEOCN | 45.15% | 908 | 0.0 | Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA27s00318g PE=4 SV=1 |
| UniRef50_A0A0J9XKG6 | 45.15% | 908 | 0.0 | Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKG6_GEOCN |
| A0A060T9D1_BLAAD | 40.68% | 907 | 0.0 | ARAD1C43516p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43516g PE=3 SV=1 |
| Q6C529_YARLI | 39.68% | 887 | 0.0 | YALI0E21549p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21549g PE=3 SV=2 |
| A0A167DEU3_9ASCO | 48.55% | 311 | 1e-77 | Adenosylmethionine-8-amino-7-oxononanoate transaminase OS=Sugiyamaella lignohabitans GN=BIO3 PE=4 SV=1 |
| BIOA_YEAST | 26.27% | 453 | 1e-27 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BIO3 PE=3 SV=1 |
| A0A1E3PED5_9ASCO | 28.61% | 374 | 2e-25 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53432 PE=3 SV=1 |
| Q5A975_CANAL | 33.33% | 150 | 6e-12 | Adenosylmethionine-8-amino-7-oxononanoate transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR01920WA PE=3 SV=1 |
| A0A1E4TK98_9ASCO | 26.62% | 154 | 2e-07 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30391 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9506
Predicted cleavage: 42
Protein family membership
- Dethiobiotin synthase BioD (IPR004472)
- Aminotransferase class-III (IPR005814)
Domains and repeats
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Domain
-
Domain
Detailed signature matches
no IPR
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-
PF13500 (AAA_26)
Protein sequence
>MCA_01181_1 MSAIKAFLSPKLRAFQIYGANTEVGKTIFSTALCRQAAKRLDSKSNSGVNYIKPVSTGEFQDADINHIQKYSPETKASGL FQYSTPVSPHLAVGIDGQEPPKDGYIVDLIHEKLTQLSAKPQSGSPSWAFVETAGGVMSPGPSGTPQADIYRPLRLPGVL VGDSKLGGVSSTISAYESLRLRGIDTNILLIFQDLEKSSSIEYQNWKFLEKYFEEKRRDAAWKDSVPHVVSLPHPPPVDI SNKEKDALQMQEYYEYLSSLTSPQKSMQYAIEYLETVHQDRIHHLREMTTKASETVWYPFSQHSKISPQTILAIDSAHGD FFQAVTSTNTNTTTIPSKEENNIQDTDSNSCSLLGPYFDASASWWTQGLGHGNADLALAAGYAAGRYGHVIFADTVHDGA LKLAEKVLAVNGVNRLKRVFFSDNGSTGIEVALKMAFKAVESRYGLSSKKKDVGVIGLKRSYHGDTIGSMDACEQSPYNE QVHWYNGKGIWLEYPQMKVKDGEWVVEIPNELVKEGLSFHGNESESRQKEAGNNTTVVDTKTFRSLEEIFNFEARTTELQ RYKKHIHQVIVQAVKKGNIFGAVIMEPILLGAGGMASIDPLFQKALVETVRESPTLFNRDNDDIATSSSKDKSTWSGLPV IFDEVFTGLYRLGAKSCAADLLQTEPDILINAKLLTGGLLPLAVTLASDSIFKSFLSPSKLDGLLHGHSYTAHPVGCSVA VESLNTLQRLDIESSAFVPTTTTTTTTTIDQQQEDVEKVKPSEWAIAKQNWAQEYYNISNNNTTENTQKCWSFWSKQFVE NISSSPQVEESFAMGCVLVLKLRDEDGVSGYSSNAVDKFKMYLKSRRQNGLLLSTDDNTKNNNETEFSQNLLPFDIHIRG LGNVLYFMTGLKPDLRTIKSLEDLLLDCFSK
GO term prediction
Biological Process
GO:0009102 biotin biosynthetic process
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0004141 dethiobiotin synthase activity
GO:0005524 ATP binding
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Cellular Component
None predicted.