Protein

MCA_01138_1

Length
591 amino acids

Browser: contigA:3624406-3626256-

RNA-seq: read pairs 1774, FPKM 37.0, percentile rank 58.6% (100% = highest expression)

Protein function

KEGG:K10599PRPF19 pre-mRNA-processing factor 19 [EC:2.3.2.27]
EGGNOG:0PK49FG02706.1cell cycle control protein
SGD closest match:S000003959PRP19Pre-mRNA-processing factor 19
CGD closest match:CAL0000186688orf19.6740E3 ubiquitin-protein ligase

Protein alignments

%idAln lengthE-value
MIA_00871_144.98%6182e-143MIA_00871_1
A0A0J9X3L2_GEOCN37.50%6085e-109Similar to Saccharomyces cerevisiae YLL036C PRP19 Splicing factor associated with the spliceosome OS=Geotrichum candidum GN=BN980_GECA01s10471g PE=4 SV=1
UniRef50_A0A0J9X3L237.50%6081e-105Similar to Saccharomyces cerevisiae YLL036C PRP19 Splicing factor associated with the spliceosome n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X3L2_GEOCN
A0A060SZT6_BLAAD34.72%5997e-84ARAD1C11132p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11132g PE=4 SV=1
A0A161HJT2_9ASCO34.17%6003e-79E3 ubiquitin-protein ligase PRP19 OS=Sugiyamaella lignohabitans GN=PRP19 PE=4 SV=1
A0A1E3PD61_9ASCO63.77%1387e-54Prp19-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10432 PE=4 SV=1
Q6CD42_YARLI60.14%1384e-53YALI0C03982p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C03982g PE=4 SV=1
Q5ADV1_CANAL42.52%2147e-36E3 ubiquitin-protein ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6740 PE=4 SV=1
A0A1E4TIZ9_9ASCO56.25%964e-29Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30060 PE=4 SV=1
PRP19_YEAST40.43%1413e-25Pre-mRNA-processing factor 19 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP19 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1728
Predicted cleavage: 31

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 591

Detailed signature matches

  1. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  2. Domain IPR003613
    U box domain
    1. PS51698 (U_BOX)
    2. PF04564 (U-box)
    3. SM00504 (Ubox_2)
  3. Domain IPR013915
    Pre-mRNA-splicing factor 19
    1. PF08606 (Prp19)
  4. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  5. Domain IPR017986
    WD40-repeat-containing domain
    1. SSF50978 (WD40 repe...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SSF57850 (RING/U-box)
  3. cd16656 (RING-Ubox_...)

Residue annotation

  1. dimer interface cd...

Protein sequence

>MCA_01138_1
MICSISGEPAKTPVISPKSGRVFEQSLIESYISQNGTDPFSQEPLTVEELIVIKTDSPAAVPPRPPQLNSIPSLLSSLQN
QWDAFALETFSLRQQLAKARQELSTALYYHDASLRVISRLTEERDEARASLAQLSASIGTSLAQPESAKANGGAAVDDSQ
QESVEEVGERLVLPSSQLEKIIVTRDTLIASRKKRKHEFGNYATAEEVSLALTALSKPSKQFFTNVQSFSLNPSTLQFIL
SGGAASKAGIFNALSPSSNNTLFTSKSGIITSSLWINDSTVALGTKTGIIELYSVEIPSGEGPDLKPELVSSDPVATIDV
ASKTDSQDSATIQTLKIHPTGDLLLSLTSHSLVSLHDISDKENPKTLSEFTSSSPYSTLDIHPDGMLLALGHASTPTIDI
QLFESETSGSSLELPEEYYNGHSKDQIHVSSISFAENGYWLAASYAVSNNDKEDSMDVDNKSFDIIGTVFIWDLRKQKIG
HVVKFPSIISEVSTALSAAKSPLKKLSSLGIDRVQFDKSSTFLAAKFYTSLAVVSYVKAEKKWSSSIGEEEKDLFNFKAS
HEIADVAWGPLAKYLYIITQKGAIQTFGLNK

GO term prediction

Biological Process

GO:0016567 protein ubiquitination

Molecular Function

GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding

Cellular Component

None predicted.