Protein

MCA_01106_1

Length
364 amino acids


Browser: contigA:3516318-3517475-

RNA-seq: read pairs 942, FPKM 31.9, percentile rank 54.4% (100% = highest expression)

Protein function

EGGNOG:0PRWQFG10137.1Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region (By similarity)
SGD closest match:S000004289YHC1U1 small nuclear ribonucleoprotein C
CGD closest match:CAL0000200741YHC1U1 small nuclear ribonucleoprotein C

Protein alignments

%idAln lengthE-value
MIA_00585_161.11%901e-30MIA_00585_1
A0A1E3PSL3_9ASCO52.13%943e-23Zf-U1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81266 PE=3 SV=1
UniRef50_A0A1E3PSL352.13%947e-20Zf-U1-domain-containing protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PSL3_9ASCO
A0A060T5T3_BLAAD47.37%953e-23ARAD1B06292p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06292g PE=3 SV=1
RU1C_CANAL64.58%483e-15U1 small nuclear ribonucleoprotein C OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YHC1 PE=3 SV=1
RU1C_YEAST59.52%425e-12U1 small nuclear ribonucleoprotein C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHC1 PE=1 SV=1
A0A1E4TCI3_9ASCO37.97%796e-10Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4045 PE=3 SV=1
A0A0J9XHX3_GEOCN68.75%321e-08Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA15s02848g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0707

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 250 300 364

Detailed signature matches

    1. SSF57667 (beta-beta...)
    1. SM00451 (ZnF_U1_5)
    1. PS50171 (ZF_MATRIN)
    1. PF06220 (zf-U1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_01106_1
MPKYYCDYCGSSLTHDSMSVRKSHSVGKHHIKLVIDYYETVAIEDGLLPESLLTAYVQPNGVRMVNPHLESILNPRNPLD
QTEQLSEFVKGAPANITAIPEISAQVYAGETGQEILNSHQAQIANQPKALPAITETEEPDASFIPNNTNNSNIPIPFQPS
STSSEKGDFGYGKHNSSYSSNNQSNPDVLANQFLESIAIQAAPLNDNSQNNRFSGTPNNRNSGGYGYNSNNQHGNRDYRD
NRENIPTNYNSGHRSPGNSNPSYGNRGDRFDNNNNYKRRYPNNGPGYGNQSDKGYSNNNNNNYHSRGFGGGNQGNRNYGN
NDRDRERDRNAPYSRNYRQDYHNNNSGGGHYQQRYNRGSRDRDE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus