MCA_01097_1
Gene name: MCM6
Description: DNA replication licensing factor MCM6; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex
Browser: contigA:3494581-3497467+
RNA-seq: read pairs 1268, FPKM 16.3, percentile rank 35.9% (100% = highest expression)
Protein function
| Annotation: | MCM6 | DNA replication licensing factor MCM6; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex | |
|---|---|---|---|
| KEGG: | K02542 | MCM6 | DNA replication licensing factor MCM6 [EC:3.6.4.12] |
| EGGNOG: | 0PG2R | MCM6 | DNA replication licensing factor MCM6 |
| SGD closest match: | S000003169 | MCM6 | DNA replication licensing factor MCM6 |
| CGD closest match: | CAL0000192979 | MCM6 | DNA helicase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X5Q5_GEOCN | 66.26% | 972 | 0.0 | DNA helicase OS=Geotrichum candidum GN=BN980_GECA02s05345g PE=3 SV=1 |
| MIA_00609_1 | 64.27% | 1002 | 0.0 | MIA_00609_1 |
| A0A1E3PL63_9ASCO | 62.17% | 933 | 0.0 | DNA helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_58042 PE=3 SV=1 |
| A0A167DE40_9ASCO | 64.37% | 887 | 0.0 | DNA helicase OS=Sugiyamaella lignohabitans GN=MCM6 PE=3 SV=1 |
| A0A060SZW1_BLAAD | 60.74% | 894 | 0.0 | DNA helicase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07370g PE=3 SV=1 |
| A0A1D8PS48_CANAL | 58.76% | 873 | 0.0 | DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MCM6 PE=3 SV=1 |
| MCM6_YEAST | 55.70% | 930 | 0.0 | DNA replication licensing factor MCM6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCM6 PE=1 SV=2 |
| UniRef50_P53091 | 55.70% | 930 | 0.0 | DNA replication licensing factor MCM6 n=47 Tax=Saccharomycetales TaxID=4892 RepID=MCM6_YEAST |
| A0A1E4TM52_9ASCO | 54.51% | 886 | 0.0 | DNA helicase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_23657 PE=3 SV=1 |
| Q6CED4_YARLI | 52.25% | 934 | 0.0 | DNA helicase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B16544g PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0272
Protein family membership
- DNA replication licensing factor Mcm6 (IPR008049)
- Mini-chromosome maintenance protein (IPR031327)
Domains and repeats
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Domain
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Domain
Detailed signature matches
no IPR
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mobidb-lite (disord...)
Protein sequence
>MCA_01097_1 MSQADSLPSDGFTPAPNSYLTSSPRHQARSSPAVWNRFSNLPTSTGQTPSSEHFAQSPYVPPSRDREGPNGQTDRDMESL MMLQRRNVLPTQVRKTHDITGEKVGESFVRFLENFKEQTDENEFDDQTDIEDDSSRYYIAQIHGMKHFGLSTLYVDYEHL RTAEDGVLAEAITEQFYRFLPHLQRGLQVLIRRYEPSLLQPQGMGGDAASALGGDNANLDDEKIFRLAFYNLPVINRIRD LRSNRIGSLMSISGTVTRTSEVRPELYKAHFTCDVCRSAIRNVEQNFKYTEPKACSNPSCDNKVAWTLNINKSHFVDWQK VRIQENSNEIPTGSMPRTLDVILRGEIVDRAKAGDKCVFTGTEIVIPDVSQLGLPGVKPSSVREGKGQGRTAEGLNSGVT GLESLGVRDLTYKMAFLANMVQEADARDASKGDVRGDGNQGEEEQEQFLASLSDAEVEELRRMVRDDHVYANLVDSIAPT VWGHNIIKKGILLQLMGGVHKTTIEGINLRGDINVCIVGDPSTSKSQFLKYVTGILPRAVYTSGKASSAAGLTAAVVKDE ETGEYTIEAGALMLADNGICAIDEFDKMDLADQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPLGGRYNRKTSLR ANINMSAPIMSRFDLFFVIVDDPNERIDRELADHIVDLHMRKDEAIEPPYTTEQLQRYIRYARTFKPKMTKRAREFMVQK YKELRSDDSQGLGRNSYRITVRQLESMVRLCEAIARANCVREITPEFVEEAFDLLRQSIIHVDHDDIEVEGDEEIVNLED GHDESNEDDDTHNEITNGGAEPEEETQEIAPNNSTSRDSATPQPDHSDVNSAPRKPKQKVKITYEKYTAMTKLLIQHIND DDADDGNGVTREELIKWYLETQEDKINSVADLKMEEELVKMVVNKLLKDNILMEMRGEGFPEEDGQESERKILIRHPNTV I
GO term prediction
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Cellular Component
GO:0005634 nucleus
GO:0042555 MCM complex