Protein
MCA_01086_1
Length
1,235 amino acids
Gene name: YAK1A
Description: Similar to dual specificity protein kinase Yak1; in S. cerevisiae a component of a glucose-sensing system that inhibits growth in response to glucose availability
Browser: contigA:3463818-3467886+
RNA-seq: read pairs 2884, FPKM 28.8, percentile rank 51.6% (100% = highest expression)
Protein function
| Annotation: | YAK1A | Similar to dual specificity protein kinase Yak1; in S. cerevisiae a component of a glucose-sensing system that inhibits growth in response to glucose availability | |
|---|---|---|---|
| KEGG: | K18670 | YAK1 | dual specificity protein kinase YAK1 [EC:2.7.12.1] |
| EGGNOG: | 0PGCF | YAK1 | protein kinase Yak1 |
| SGD closest match: | S000003677 | YAK1 | Dual specificity protein kinase YAK1 |
| CGD closest match: | CAL0000193813 | YAK1 | Serine/threonine protein kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05948_1 | 73.04% | 497 | 0.0 | MIA_05948_1 |
| A0A060T5A0_BLAAD | 74.77% | 444 | 0.0 | ARAD1B09130p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B09130g PE=4 SV=1 |
| A0A0J9X4J9_GEOCN | 73.23% | 452 | 0.0 | Similar to Saccharomyces cerevisiae YJL141C YAK1 Serine-threonine protein kinase that is part of a glucose-sensing system OS=Geotrichum candidum GN=BN980_GECA02s05235g PE=4 SV=1 |
| UniRef50_A0A0J9XCT9 | 71.95% | 435 | 0.0 | Similar to Saccharomyces cerevisiae YAR019C CDC15 Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCT9_GEOCN |
| Q6CBP9_YARLI | 69.53% | 443 | 0.0 | YALI0C16665p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C16665g PE=4 SV=1 |
| A0A1E3PSD3_9ASCO | 65.75% | 435 | 0.0 | Kinase-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4608 PE=3 SV=1 |
| YAK1_YEAST | 60.31% | 446 | 0.0 | Dual specificity protein kinase YAK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YAK1 PE=1 SV=1 |
| A0A161HI61_9ASCO | 73.01% | 352 | 0.0 | Serine/threonine protein kinase YAK1 OS=Sugiyamaella lignohabitans GN=YAK1 PE=4 SV=1 |
| A0A1E4TKD6_9ASCO | 60.82% | 439 | 0.0 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12805 PE=3 SV=1 |
| A0A1D8PH81_CANAL | 51.05% | 476 | 6e-152 | Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YAK1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0063
Predicted cleavage: 74
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1235
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
cd14212 (PKc_YAK1)
-
mobidb-lite (disord...)
Residue annotation
-
ATP binding site c...
-
active site cd14212
-
polypeptide substr...
-
activation loop (A...
Protein sequence
>MCA_01086_1 MDHNHSYYSPQAPTNKSDSNNNNNNSQSSSSFQGHIDYNSSTFTPALNPPPAPSPMAYSPIPAGSSPNSMYRQGPTSAAQ PGGLNINAYNSPSPTISMNPYMTIPEEATPSTRHYPHHSNSTQHYQQHSQQFSNMRQNQQIPSPSSNALKLSSHGSTSSL MSYDESANSSTPSKASHYSPSSNSHTSTNRLHFNPQSSPRLQTGAPQSYTQQQSGPLKGLNVSTTGLKTSGTPNLGPPMY NQNQSGSQMQSPNTPISGYSFNNWYPSTASQKQQHSYVSSQASASEVGGNNNVLSSSPIRGSNGLGTNTAQEKSNYGSFT YQQINSPTTSSSSSSSVDATTTLPPPVKSSRNMTPNSSTMASTKSFPSGGISSSQSLPQLTHLQQSHYQQHSPPSLHIQS PSQPSIRQQQTPQQSQFQLQQPNHQKSHSYSRSSPSQTMSAQQMALMAATAHHRLSTDNPDVYARNVNIENATPSNTSSP SSPIRQMHAQSASISSSTARPHSFSMSHPPGQHIGSPNPQNETGSYYSASPNPQSVPVKYPPSFRRIRSISELAPIVHDQ PKFRRALPEGGSLSPLAALTRQLPTTYHICNPEFNYQSSRNPRRVLTKPSEGKLNHGYDNSENDYILYVNDILGIDEQRR YLVLDILGHGTFGQVAKCQNMVTKEILAVKVIKSKPAYYKQSLMEVSILQHLNTRIDENNEHNLLRLKDHFMHKDHLCLV FELLSSNLYELIKRNKFRGLSINLVRVFSQQLLDSLMVLKKANIIHCDLKPENILLKSIDKPDIKVIDFGSACHERKTVY TYIQSRFYRSPEVLLGIPYSASIDMWSLGCIVAELFLGLPIFPGTSEYNQLSRIIETLGMPPNWMLDLGNSTKQFMTQYV DEYGNKRYSLKTPEQYSKEFLVKEEPSKKYFQFTKLDDIIMKYPLPKENMSQEEIDAEIENRKSLLDFIKGLLNINPIER WTPQAAAGHPFITGQRFTGPYVPGFSNPALAYNKHVPISQQQQQQQHQQQQQQQQQKYTSYQKQHQQEYQQGRPEKGPIL PLASEQAGPSQKQQIYYGMGSQAPATNSIPGALPPYTANNAASIQQKPPHPQQMKPQIQGYHGQSQMASTGWSARRPRAS TIGNMDPIPQPIQRATALMNPAQPIRAQPSPAYIPPPELFEKNNNGLMVNRVRVGNSGLSNVTSNSEMNTNQNGSYYNNN DNSNNKPNAENRNNGNSNSGDVVRNLENGAISYWS
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
Cellular Component
None predicted.