Protein

MCA_01032_1

Length
467 amino acids

Gene name: YPK3

Description: Putative serine/threonine protein kinase similar to S. cerevisiae Ypk3 and S. pombe Psk1; both homologs act as S6 kinases.

Browser: contigA:3269794-3271198+

RNA-seq: read pairs 1337, FPKM 35.3, percentile rank 57.3% (100% = highest expression)

Protein function

Annotation:YPK3Putative serine/threonine protein kinase similar to S. cerevisiae Ypk3 and S. pombe Psk1; both homologs act as S6 kinases.
KEGG:K22008PSK1 serine/threonine-protein kinase Psk1 [EC:2.7.11.1]
EGGNOG:0PH4BPSK1AGC family protein serine threonine kinase domain-containing protein
SGD closest match:S000000232YPK3Serine/threonine-protein kinase YPK3
CGD closest match:CAL0000193910orf19.6275Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_00263_165.59%4970.0MIA_00263_1
A0A0J9XJD8_GEOCN59.75%4770.0Similar to Saccharomyces cerevisiae YKL126W YPK1 Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p OS=Geotrichum candidum GN=BN980_GECA23s00351g PE=4 SV=1
A0A1E3PNJ8_9ASCO62.41%4156e-161Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45237 PE=4 SV=1
A0A161HGH9_9ASCO56.78%4351e-160Uncharacterized protein OS=Sugiyamaella lignohabitans GN=YPK3 PE=4 SV=1
Q6CBU3_YARLI58.10%4201e-150YALI0C15444p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C15444g PE=4 SV=1
UniRef50_Q6CBU358.10%4203e-147YALI0C15444p n=9 Tax=saccharomyceta TaxID=716545 RepID=Q6CBU3_YARLI
A0A060T391_BLAAD58.66%4331e-149ARAD1C38786p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38786g PE=4 SV=1
A0A1E4T9W0_9ASCO56.58%3574e-125Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20311 PE=4 SV=1
Q5AAN6_CANAL48.59%3541e-97Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6275 PE=4 SV=1
YPK3_YEAST39.58%4326e-82Serine/threonine-protein kinase YPK3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPK3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0369

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 467

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. Domain IPR000961
    AGC-kinase, C-terminal
    1. SM00133 (pkinase_C_6)
    2. PS51285 (AGC_KINASE...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd05123 (STKc_AGC)
  4. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd05123
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MCA_01032_1
MITEIFDFEDENTPSTYKSKISINTHIGDEVDELCDTLAELNPSSSPVATRPISIQANGHRRNSSSGFLPGSADGRAGRS
LEIGIRSPFVSSFAENYVPSSPVDTISPVAFNEPQKKLQPSDFKPLKVLGQGTYGKVLLVRETRTNRLFAQKQLKKASMI
VEEKHVVQTRTEREILESVRHPYIVKLFYAMQDKEKLYLILEYAQGGELFNYLADQSMLSEDAVQFYCAEMILALYHLHV
NVGVVYRDLKPENCLLDSEGHLVLTDFGLSKVATDSDASCRTFLGTPEYMAPEILEGLEYDYAVDWWSLGAVCYDLLTGN
PPYPGDDHKTILGKIWKSKKVDFPFYLTRDAQNFMSRLLVRNPKSRWGYKDIEKIKNHSFFDGIEWDLLERRDPNIVPPI
VPIITDPEKAENFSKEFTDIPLSPPVHNSHMDIPNRNSGKGFGFDEDSHPFRGFSFTASKSFIDSEY

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.