Protein
MCA_01024_1
Length
404 amino acids
Gene name: MEK1
Description: Meiosis-specific serine/threonine-protein kinase Mek1; in S. cerevisiae promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids
Browser: contigA:3252888-3254612+
RNA-seq: read pairs 70, FPKM 2.1, percentile rank 12.0% (100% = highest expression)
Protein function
| Annotation: | MEK1 | Meiosis-specific serine/threonine-protein kinase Mek1; in S. cerevisiae promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids | |
|---|---|---|---|
| KEGG: | K12776 | MEK1 | meiosis-specific serine/threonine-protein kinase MEK1 [EC:2.7.11.1] |
| EGGNOG: | 0PJPB | MEK1 | meiosis-specific serine threonine-protein kinase mek1 |
| SGD closest match: | S000005878 | MEK1 | Meiosis-specific serine/threonine-protein kinase MEK1 |
| CGD closest match: | CAL0000193545 | orf19.1874 | Serine/threonine protein kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01166_1 | 57.98% | 357 | 1e-149 | MIA_01166_1 |
| A0A0J9XGT3_GEOCN | 52.71% | 351 | 5e-125 | Similar to Saccharomyces cerevisiae YOR351C MEK1 Meiosis-specific serine/threonine protein kinase OS=Geotrichum candidum GN=BN980_GECA15s02793g PE=3 SV=1 |
| UniRef50_A0A0J9XGT3 | 52.71% | 351 | 1e-121 | Similar to Saccharomyces cerevisiae YOR351C MEK1 Meiosis-specific serine/threonine protein kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XGT3_GEOCN |
| MEK1_YEAST | 39.33% | 417 | 3e-91 | Meiosis-specific serine/threonine-protein kinase MEK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MEK1 PE=3 SV=1 |
| A0A1D8PI13_CANAL | 41.52% | 395 | 1e-86 | Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1874 PE=3 SV=1 |
| A0A1E3PS39_9ASCO | 41.58% | 291 | 2e-64 | Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48891 PE=4 SV=1 |
| A0A060TB87_BLAAD | 33.80% | 284 | 7e-43 | ARAD1B13838p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B13838g PE=3 SV=1 |
| Q6C079_YARLI | 30.77% | 351 | 7e-40 | Serine/threonine-protein kinase RAD53 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27093g PE=3 SV=1 |
| A0A1E4THZ6_9ASCO | 30.03% | 363 | 6e-36 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14634 PE=3 SV=1 |
| A0A167CX64_9ASCO | 31.00% | 271 | 1e-33 | Calmodulin-dependent protein kinase CMK2 OS=Sugiyamaella lignohabitans GN=CMK2 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1514
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
404
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
phosphopeptide bin...
-
ATP binding site c...
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active site cd05117
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polypeptide substr...
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activation loop (A...
Protein sequence
>MCA_01024_1 MSKSISIGRNVKCDYTINDTIVSSSHCTIYAVQFDPVCAPMVYCHDSSLNGTFINDRLIGKGNTEILTNGDIISICSTEK FKFLSNSAYALPKTKYPEVPNTTVSKFHLSDRVLGVGSFGEVYLAHHIDTRALIACKVSKIVERKGFHPTTEVNILKCLN HPNILAMHETVIIDDKLFLFEELMTGGDLFSYLIGPNDQLRHLPEYEALFICFQILKALKYLHSLNIAHRDLKLDNILLE RPFPGSRIVLGDFGIASSLNASRKVMSTVIGTPEYSAPEVGFDHSRKGIGYTLKCDMWSLGVILHILFTGISPFFDEEDV KQTALNASSGEINLNTPEWSTISEKGKDFVKKLLQVNPSNRLSSFQAFNHLWINRFKSHLEDLYSENVFKPWNKQNKEYK EYEF
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
Cellular Component
None predicted.