Protein

MCA_00997_1

Length
516 amino acids


Browser: contigA:3164146-3165993+

RNA-seq: read pairs 457, FPKM 10.9, percentile rank 27.4% (100% = highest expression)

Protein function

EGGNOG:0PH7IFG06297.1Protein-tyrosine phosphatase
SGD closest match:S000002389PTP1Tyrosine-protein phosphatase 1
CGD closest match:CAL0000179853PTP1Tyrosine protein phosphatase

Protein alignments

%idAln lengthE-value
A0A0J9X9R7_GEOCN50.00%1981e-54Similar to Saccharomyces cerevisiae YDL230W PTP1 Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo OS=Geotrichum candidum GN=BN980_GECA05s03640g PE=4 SV=1
UniRef50_A0A0J9X9R750.00%1982e-51Similar to Saccharomyces cerevisiae YDL230W PTP1 Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9R7_GEOCN
MIA_02019_154.32%1623e-52MIA_02019_1
Q6BZT9_YARLI37.18%1565e-26YALI0F30943p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F30943g PE=4 SV=1
PTP1_YEAST37.95%1952e-24Tyrosine-protein phosphatase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PTP1 PE=1 SV=1
A0A1E3PH82_9ASCO38.67%1502e-21Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52384 PE=4 SV=1
A0A167FQY2_9ASCO29.84%1912e-19Tyrosine protein phosphatase PTP1 OS=Sugiyamaella lignohabitans GN=PTP1 PE=4 SV=1
Q5A399_CANAL37.33%1503e-17Tyrosine protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PTP1 PE=4 SV=1
A0A1E4TKC3_9ASCO45.05%1112e-17Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18571 PE=4 SV=1
A0A060T6P3_BLAAD28.72%1952e-15ARAD1C21802p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C21802g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1198

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 250 300 350 400 450 516

Detailed signature matches

    1. SSF52799 ((Phosphot...)
    1. PR00700 (PRTYPHPHTASE)
    2. PS50055 (TYR_PHOSPH...)
    3. SM00194 (PTPc_3)
    4. PF00102 (Y_phosphatase)
    1. SM00404 (ptp_7)
    1. PS50056 (TYR_PHOSPH...)
    1. PS00383 (TYR_PHOSPH...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00047 (PTPc)
  2. mobidb-lite (disord...)

Residue annotation

  1. active site cd00047

Protein sequence

>MCA_00997_1
MLKKIIPVKSTSNQNSTINEDKIKRKIWDSMPLFLQSSNQAQVKFQEICDDESKRIKRALERPNERLGWSFQDALKNPSR
NRYSNILPFDNNRIRLAVNPGGNDYINASLITLDIGKADSIAPKQYIATQGPVRETVPHFWQMLYSMSQHSQQYNSESIV
IVMLTPLIENSRHEACAPYWPRFENHSIDIPPDSSFGKSLKVTCVSVKKYGPKTPITLSPSYTESTEFFCPPSYFASPIE
SSTFQSNTSSSLSASSSNPKHQSPTTSPKASKTSNSQNQHHRRHSETQVTSNDVKLLPPFPHTHTIMHLTCPEDGVRKVI
HHIYVDSWVDFGRPKEEVDIANLIYLANSLNHDSPSKSISTINYNQQNSSFFSPSKRTSDSPGSKDQMPLVVHCSAGVGR
TGVFLAMDYLLTRSKLLLPELKVNKNIGYKYTYNQPQLKQQNDDGEKNSNIPQQHDIMANNRRMMIASSDPIYSLVSSMR
EQRLGMVQRLTQYKYIYEITRMKFYRKQKAILMNKK

GO term prediction

Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

Molecular Function

GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity

Cellular Component

None predicted.