Protein

MCA_00995_1

Length
826 amino acids

Browser: contigA:3159821-3162498+

RNA-seq: read pairs 1949, FPKM 29.1, percentile rank 51.9% (100% = highest expression)

Protein function

KEGG:K18083MTMR6_7_8 myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
EGGNOG:0PH67FG05432.1phosphatase
SGD closest match:S000003871YMR1Phosphoinositide 3-phosphatase
CGD closest match:CAL0000182833orf19.4744Phosphatidylinositol-3-phosphatase

Protein alignments

%idAln lengthE-value
MIA_06191_159.12%6850.0MIA_06191_1
A0A0J9XBF7_GEOCN62.50%6000.0Similar to Saccharomyces cerevisiae YJR110W YMR1 Phosphatidylinositol 3-phosphate (PI3P) phosphatase involved in various protein sorting pathways OS=Geotrichum candidum GN=BN980_GECA06s05092g PE=3 SV=1
UniRef50_A0A0J9XBF762.50%6000.0Similar to Saccharomyces cerevisiae YJR110W YMR1 Phosphatidylinositol 3-phosphate (PI3P) phosphatase involved in various protein sorting pathways n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XBF7_GEOCN
A0A060T0T4_BLAAD56.88%5960.0ARAD1C11000p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11000g PE=3 SV=1
A0A1E3PKZ6_9ASCO53.94%6340.0Phosphatases II OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51371 PE=3 SV=1
Q6C4T9_YARLI55.53%5060.0YALI0E23738p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23738g PE=3 SV=1
A0A1E4TAL4_9ASCO46.71%5932e-166Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32262 PE=3 SV=1
YMR1_YEAST39.28%6678e-138Phosphoinositide 3-phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YMR1 PE=1 SV=1
A0A1D8PEF4_CANAL38.43%4972e-103Phosphatidylinositol-3-phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4744 PE=3 SV=1
A0A167CIH1_9ASCO52.74%3288e-103Phosphatidylinositol-3-phosphatase YMR1 OS=Sugiyamaella lignohabitans GN=YMR1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1848

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 826

Detailed signature matches

  1. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
    2. SSF50729 (PH domain...)
  2. Domain IPR029021
    Protein-tyrosine phosphatase-like
    1. SSF52799 ((Phosphot...)
  3. Domain IPR010569
    Myotubularin-like phosphatase domain
    1. PS51339 (PPASE_MYOT...)
    2. PF06602 (Myotub-rel...)
  4. SITE IPR016130
    Protein-tyrosine phosphatase, active site
    1. PS00383 (TYR_PHOSPH...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00995_1
MEFIKIAKVPDVICTRFGKSTKGTLHLTAHHLIFRDSQTKSEIWICYPIIANVERRYSGNDTYSSEIPSSSLSSPNLTAT
SQSSDGIQSNAPVLSHSNHNTSTIRIRCKDFCFLAFKFQSDDVAKDVFDSIMKLTCVPSINKLYAFMYKPFSIEKTINGW
ELYNPLNEFRRMGVLKPGSRWRVSEINSDYNFSPTYPSFIVVPSSVSDTVISYGGKFRSKTRFPALSYYHQFNGCTITRC
SQPMVGLKQNRSVQDEKLVEAIFNSNQQPDKTGNKQDNLIVDARPTANAVAQTALGAGSENMDNYKGSRKIYLGIDNIHV
MRESLNRIVDALKDGDISSAPPNKELLYKSNWLRYISTMMEGAVIIANHIHYNFSHVLIHCSDGWDRTSQLSSLAQIMLD
PYFRTLDGFMVLVEKEWLSFGHRFAERSGYLNNPRNFVEVSATSNQAGNMLRDVGNKLVKTNHLKYTSPIFHQFLDAVYQ
LLVQFPDRFEFSERFLRRLLYHTYSCQYGTFLCNNEAERKQYKIKESTRSVWDYFLARRSEFLNHSANYDREREFSYDSE
KTVLIANPKQLKYWAELFGRTSEEMNSRIKPEQLVAATSNMIISSPGAPSSSYKEPSTSPSVTDTCSAVSPPTKNGSRAP
SSSSGFFSRPQTSSLNNSSSSSNILSDMKKSSSKNESNDSVEIDKGSLSSSYSEILPNTSGSAEQLSSSSYFTSTNTEKF
PKQSIQSTSFNRIESSTESGNNYSNGIRSVSLQTTTVVQADKNDTESKNAVAKEGIDDDTDKTNTEVIEQDSSLDARKYA
QFSAMTYDDDFSSYSSKKKGGLGGLF

GO term prediction

Biological Process

GO:0016311 dephosphorylation

Molecular Function

GO:0004725 protein tyrosine phosphatase activity

Cellular Component

None predicted.