MCA_00986_1
Gene name: GLT1
Description: Glutamate synthase [NADH]
Browser: contigA:3135510-3141903+
RNA-seq: read pairs 6282, FPKM 36.4, percentile rank 58.2% (100% = highest expression)
Protein function
Annotation: | GLT1 | Glutamate synthase [NADH] | |
---|---|---|---|
KEGG: | K00264 | GLT1 | glutamate synthase (NADPH/NADH) [EC:1.4.1.13 1.4.1.14] |
EGGNOG: | 0PGFW | GLT1 | glutamate synthase |
SGD closest match: | S000002330 | GLT1 | Glutamate synthase [NADH] |
CGD closest match: | CAL0000182870 | GLT1 | Glutamate synthase (NADH) |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_05201_1 | 90.52% | 2121 | 0.0 | MIA_05201_1 |
A0A0J9X9S4_GEOCN | 85.43% | 2114 | 0.0 | Similar to Saccharomyces cerevisiae YDL171C GLT1 NAD(+)-dependent glutamate synthase (GOGAT) OS=Geotrichum candidum GN=BN980_GECA06s01880g PE=4 SV=1 |
A0A060T400_BLAAD | 81.45% | 2119 | 0.0 | ARAD1C37774p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37774g PE=4 SV=1 |
A0A167EHB1_9ASCO | 81.86% | 2128 | 0.0 | Glutamate synthase (NADH) OS=Sugiyamaella lignohabitans GN=GLT1 PE=4 SV=1 |
A0A1E3PSI4_9ASCO | 81.23% | 2120 | 0.0 | Glutamate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81242 PE=4 SV=1 |
Q6CDZ4_YARLI | 79.77% | 2130 | 0.0 | YALI0B19998p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B19998g PE=4 SV=1 |
A0A1E4TGN6_9ASCO | 76.94% | 2121 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31714 PE=4 SV=1 |
A0A1D8PDU9_CANAL | 74.04% | 2119 | 0.0 | Glutamate synthase (NADH) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GLT1 PE=4 SV=1 |
UniRef50_A0A179GPQ5 | 73.60% | 2129 | 0.0 | Glutamate synthase n=8 Tax=Hypocreales TaxID=5125 RepID=A0A179GPQ5_9HYPO |
GLT1_YEAST | 64.59% | 2132 | 0.0 | Glutamate synthase [NADH] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GLT1 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0020
Protein family membership
- Glutamate synthase, eukaryotic (IPR012220)
- Glutamate synthase, NADH/NADPH, small subunit 1 (IPR006005)
Domains and repeats
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Domain
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Domain
Detailed signature matches
Residue annotation
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active site cd00713
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dimer interface cd...
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FMN binding site c...
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active site cd02808
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substrate binding ...
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3Fe-4S cluster bin...
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domain interface c...
Protein sequence
>MCA_00986_1 METINNEEINEQYAPYDYVNTPENNSWAGALPVKQGLYDPEFEKDACGVGFSCHIKGKVSHKIVSDAKDLLCKMTHRGAV GADARDGDGAGVMTSIPHKFMVKQFETTNDFKLPPLGQYAVGNLFFKNDEQVLEQSRNILERIAESLGLRVLGWREVPRD SSLLGPAALSREPLILQPIVVLTEAYGSGNSPETTDAELFEKNFERTFERKLYILRKQSTHSIGLHNWFYICSLSNKNIV YKGQLAPVQVYQYYYDLANVDYEAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGVMKSDVFGE ELDKLYPIIEEGGSDSAAFDNVLELLVMNGVLSLPEAVMIMVPEAWQNNTDMNPKKRAFYEWAACLMEPWDGPALFTFAD GRYCGANLDRNGLRPCRYYVTDDDRMICASEVGVMDIPPESVIQKGRLRPGRMLLVDTKEGIIVDDRELKRRVSERFDFK SWASANLLTMPDLFAKLEAREGANAIESLKPKLDSFTVQNDPRLKAFGYTFEQVSLLLAPMAAEGKEALGSMGNDGPLAC LAPQPRLLYEYFRQLFAQVTNPPIDPIRESIVMSLECYIGPQGNVLEMKPNQMDRLLMPSPILSNVEFAGLSLLPKFYPS WTIDFIDITFPKSEGVAGYTRALERIAQEASEAITNHNKIIVLTDRAVNADRVAVSALLATGAVHHHLVRQKQRSKVALV VETGEAREVHHMCVLVGYGADAINPYLAIETLLKMNREGLLKQQLDDKTIVENYKHSIDGGILKVMSKMGISTLASYKGA QIFEALGIDNSVVDKCFTGTASRIKGITFDYIAEDAFTIHERGFPSRLTIKPEGLPESGEYHYRDGGDAHMNTPVAIANI QDAVRNKNEKAYETYSKNEYEATKNCTLRGLLDFDFDNSQAIPIDQVEPWTEIVRRFVTGAMSYGSISMESHSTLAVAMN RLGGKSNTGEGGEDPERSNVNEQGDTMRSAIKQIASGRFGVTSYYLSDSDELQIKMAQGAKPGEGGELPGDKVSQSIAKT RHSTPGVGLISPPPHHDIYSIEDLKQLIYDLKCSNPRARVSVKLVSEVGVGIIASGVAKAKADHILISGHDGGTGASRWT GIKYAGLPWELGLAETHQTLVLNDLRGRVIVQTDGQIKTGRDVAIACLLGAEEWGFATTPLIAMGCIMMRKCHLNTCPVG IATQDPELRKKFMGTPEHVINFFYYIANELRQIMAKLGYRTINEMVGHAEKLKVRDDLRNSKTINLDLTPLLTPAHTLRP GVATRNVRKQDHRLHVRLDNKLVDEAEVTLEKGLPVNIEAQIVNTDRALGTTLSYRISKKFGEQGLPNDTAHVYITGSAG QSFGAFLAPGITLELEGDANDYVGKGLSGGRIIIYPPTNSPFKAEENIIIGNTCLYGATSGTCFFRGVAAERFAVRNSGA TAVVEGCGDHGCEYMTGGRVVVLGPTGRNFAAGMSGGIAYVLDMAQEFNSNVNTEMVELCPLTDPAEIAFVRGLIEDHRH YTNSELADRVLTDFNRILPRFVKVFPTDYKRVLEQEKKKKEELKKAEVVDFFHNIREDPDADITNGEILRTRTPAPITGT NTPVAKKEPKVLDLEDTILDHAAEKKKAAVLKLDKTRGFKLYKRRNEKYRPATDRTKDWAELSNRLTKEELKYQTARCMD CGVPFCQSDTGCPISNIIPKWNELVFKDRWYDALQRLLMTNNFPEFTGRVCPAPCEGACVLGINEDPVGIKSVEAAIIDH GWAQGWIKPNPPPVRTGKSVAIIGSGPAGLACADQLNRAGHSVTVYERADRVGGLLMYGIPNMKLDKRVVERRTNLMRDE GVKFITNTTIGEDITVEELESQNDAVVFACGSTIARDLKIPGRELNNIMYAMQLLKWNTKALLEDNLEEVRSLLHGKNVV VIGGGDTGNDCIGTSVRHGAKSVVNFELLPKPPAARGKDNPWPQWPRIFRVDYGHTEVTAHYGKDPREYCILSKQFVGDE DGNVKGIKTVRVEWKKSESGAWQMSEVPNSEEFFPADVVLLSMGFIGPEAQNLGVERDPRGNIKTTGPSSYRIGDKFFAA GDCRRGQSLIVWGIQEGRQCARDIDIFLVGNTRLPGNGSIEQRDFEIAAK
GO term prediction
Biological Process
GO:0006537 glutamate biosynthetic process
GO:0006807 nitrogen compound metabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0003824 catalytic activity
GO:0005506 iron ion binding
GO:0010181 FMN binding
GO:0015930 glutamate synthase activity
GO:0016040 glutamate synthase (NADH) activity
GO:0016491 oxidoreductase activity
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
GO:0045181 glutamate synthase activity, NAD(P)H as acceptor
GO:0050660 flavin adenine dinucleotide binding
GO:0051536 iron-sulfur cluster binding
Cellular Component
None predicted.