Protein

MCA_00977_1

Length
1,872 amino acids

Gene name: SPO14

Description: Phospholipase D1

Browser: contigA:3108985-3114604+

RNA-seq: read pairs 2257, FPKM 14.9, percentile rank 33.9% (100% = highest expression)

Protein function

Annotation:SPO14Phospholipase D1
KEGG:K01115PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
EGGNOG:0PG35SPO14Phospholipase D1
SGD closest match:S000001739SPO14Phospholipase D1
CGD closest match:CAL0000189670PLD1Phospholipase D

Protein alignments

%idAln lengthE-value
MIA_05340_160.98%16580.0MIA_05340_1
A0A0J9X7R1_GEOCN52.65%15120.0Similar to Saccharomyces cerevisiae YKR031C SPO14 Phospholipase D OS=Geotrichum candidum GN=BN980_GECA04s00329g PE=4 SV=1
UniRef50_A0A0J9X7R152.65%15120.0Similar to Saccharomyces cerevisiae YKR031C SPO14 Phospholipase D n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X7R1_GEOCN
A0A060T4F8_BLAAD54.92%10670.0ARAD1C40744p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40744g PE=4 SV=1
Q6C5D8_YARLI62.84%7320.0YALI0E18898p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E18898g PE=4 SV=1
A0A167FHJ5_9ASCO56.94%8640.0Phospholipase D OS=Sugiyamaella lignohabitans GN=SPO14 PE=4 SV=1
A0A1E4TFB8_9ASCO55.87%7750.0Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31359 PE=4 SV=1
A0A1D8PF62_CANAL53.91%8570.0Phospholipase D OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PLD1 PE=4 SV=1
SPO14_YEAST54.46%7290.0Phospholipase D1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPO14 PE=1 SV=3
A0A1E3PH05_9ASCO49.22%7010.0Phospholipase D/nuclease OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83771 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0296

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1600 1872

Detailed signature matches

  1. Domain IPR001683
    Phox homologous domain
    1. PF00787 (PX)
    2. PS50195 (PX)
    3. SM00312 (PX_2)
    4. G3DSA:3.30.15...
    5. SSF64268 (PX domain)
  2. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
  3. Domain IPR001736
    Phospholipase D/Transphosphatidylase
    1. SM00155 (pld_4)
    2. PS50035 (PLD)
  4. Domain IPR025202
    Phospholipase D-like domain
    1. PF13091 (PLDc_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.87...
  3. PIRSF009376 (PLD_euk)
  4. SSF56024 (Phospholi...)
  5. cd01254 (PH_PLD)
  6. cd09138 (PLDc_vPLD1...)
  7. cd09141 (PLDc_vPLD1...)
  8. mobidb-lite (disord...)

Residue annotation

  1. catalytic site cd0...
  2. putative active si...
  3. catalytic site cd0...
  4. putative active si...

Protein sequence

>MCA_00977_1
MTTDAQSYSKQEVLPEKASIKAQIETAPLSSQDSEHELSTNNSFTPFTSPISYDSKHLGFTNNIQQPTSPEIEIKMEYGQ
AISPSSVNLANCSQQPEQSNQESPPTKVSWRSPFDNSTHQLKQPSELSSEYTHSITDLNRNLSTSSLGNSRAKSENYSAD
DPLDNNNTTSAINNKSLDPKEPGSNFNSPAENLSPQKSPSRPDKGKSKLLFFTNTIFKNSSKSNINTSTDGLTSRTPINS
KFMAKSDSLESQDVSKPLDEIDNQNDFKLHKSRSKSDVGVYGHIDMRQSLRQRLIRRGSNHSDTEDCSKDTIDPDLHHQE
NLSDSEIDRIHNEEESRQASRRRLNFIQRHINTPTFGSIASGNSVKNNEETPNEANSNPPETPNLDPHPGFLRRHTIFSM
EYSPPSIPLEWKDVKNKLKRFKKKKTEKQGDGSASNSGILSELIAIIPAAMIVPMAFLKDDRNIHTIPVLLHHVDFKFID
ITRNQNEKNRKYSIELSYGSGSARLQWVIIRDYRDFMGLHSRLRVASFQNVFGPKLLLPKFPSRHYVAEHMNKDETQANC
RNFGFLSPTHSIKSIKSNKSQSTAPHMASGPSSHATSTSRPPPVLNVLVDPKPKLSTIMDEDPPPLNLEPTSSSFSLGSD
VSAHSYKLFRRVQSLNGGRHLPIGSIQFSDSMREKFHESLRLALEKYLHDLFKAMRFRPEANRLFQFLELSNMSMRLAPE
NSYHGKEGYLILRSSAGSMGWRVSHWKPNELSQMIDRHTSRWYLVRESYIVCVNDISSANVTEVFMVDPNFKITHGYVGG
CPDDDTNEKRHSKASNESKGESKHQGFTFEVENSERKMKLLTTSQRQLGLWLESINHMKDHTIWSKPHRFNSFAPVRTKV
QARWFVDARDYFWTVSSAIDMAKDVIYIHDWWLSPELYLRRPPDGNQEWRIDRLLKRKAEQGVKIFIIIYRNVGQTVPID
SSWTKHSFLDLHPNIYIMRSPNQLLQNTFFWAHHEKLCLIDHIIGFLGGIDLCFGRWDTPSHVLVDDDPNAFYDPNSTNH
SQKDGQTQIWPGKDYSNPRQHDFFSLDKPYEDMYDRNEVPRMPWHDIHMMVTGQSARDITRHFVQRWNYLIRQKRPSRFT
PLLLPPADLTQEDLEELNLEGTCEVQILRSSCNWSLGIKKPESSIQNAYLKAIEQSEHFVYIENQFFISSTFYEGTEIEN
RIGDSLYERIVRAHRNNENWKCVVVIPLMPGFESEIDEKNGLSVRMIMQLQYLTISHGSESIFGKLFKKNINPEDYIQFF
SLRQWGKIGPKKRLVTEQLYIHSKTMIVDDRIAIIGSANINERSMRGNRDSEVAALIRDTAQIQSSMGGKPYMVGKFPHT
LRVRLMREHVGIDIDQLEMVESLVDQELASRTNYKYKADFDYLAWMQSVKEMSQNPGNADDTPTNKADFHSFNNLAGVDN
IGFRDKKPLSSDSRVQGNETHKLDVDGIGPDKYRKREAMDVMGVPSNAPKDAPKDAISLKNLALQYFEQLWEDLGPDAMV
RDVDDIKRQVYYYLQTKSWRRPDGNFDNIGSTANGNKVPVQFFPNQSQADDNIFQFRDMKGSNASFGMSSSPAGFNGSAS
VRSDAYGSSATYLPNGSSATNLNNPDSNGLPTSSSDRDLPNQYFYPIDPFGFSDPLSDEFYYDLWERVADQNTLLYREVF
HCQPDDEVTTWKQYIEFKELASRFARQQGQKIFDDVELDMPDEERQQLDRAVENLTNGGVETKHEKCPPGHCEPNPAEGR
SSSCFSVEGEELSPERMEELEKEAARRAAAQEEARILRENYKAMLRRRRQNRRSTRNILNTEEVYSKNIAERVMQGVRGN
LVFFPTQWLAHELDSGNWQHAIDHLPPIEIYD

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0035091 phosphatidylinositol binding

Cellular Component

None predicted.