Protein

MCA_00976_1

Length
613 amino acids

Gene name: ITR1

Description: Myo-inositol transporter; member of the sugar transporter superfamily

Browser: contigA:3106792-3108634+

RNA-seq: read pairs 189, FPKM 3.8, percentile rank 15.4% (100% = highest expression)

Protein function

Annotation:ITR1Myo-inositol transporter; member of the sugar transporter superfamily
EGGNOG:0PHGFPGUG_05324MFS sugar transporter
SGD closest match:S000002905ITR1Myo-inositol transporter 1
CGD closest match:CAL0000199303HGT19Hgt19p

Protein alignments

%idAln lengthE-value
MIA_05339_167.86%5880.0MIA_05339_1
A0A0J9X6K2_GEOCN63.78%5660.0Similar to Saccharomyces cerevisiae YMR011W HXT2 High-affinity glucose transporter of the major facilitator superfamily OS=Geotrichum candidum GN=BN980_GECA04s00318g PE=3 SV=1
A0A1E3PFN7_9ASCO61.15%5560.0Putative MFS myo-inositol transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83770 PE=3 SV=1
A0A1E4TLJ6_9ASCO55.81%5770.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1200 PE=3 SV=1
A0A060T3L5_BLAAD58.36%5620.0ARAD1C40766p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40766g PE=3 SV=1
A0A167FHJ1_9ASCO57.02%5910.0Myo-inositol transporter ITR1 OS=Sugiyamaella lignohabitans GN=ITR1 PE=3 SV=1
UniRef50_A0A1J7IJE351.62%5540.0Uncharacterized protein n=2 Tax=sordariomyceta TaxID=715989 RepID=A0A1J7IJE3_9PEZI
Q6C1A0_YARLI48.54%5810.0YALI0F18084p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F18084g PE=3 SV=1
Q5A7L9_CANAL50.00%4823e-162Hgt19p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HGT19 PE=3 SV=1
ITR1_YEAST25.98%5085e-40Myo-inositol transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ITR1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2170

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 613

Detailed signature matches

  1. Family IPR005828
    Major facilitator, sugar transporter-like
    1. PF00083 (Sugar_tr)
  2. Family IPR003663
    Sugar/inositol transporter
    1. TIGR00879
    2. PR00171 (SUGRTRNSPORT)
  3. Domain IPR020846
    Major facilitator superfamily domain
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.12...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)

Residue annotation

  1. putative substrate...

Protein sequence

>MCA_00976_1
MNRDSITEGSTVRESTLYNEKYQKELLKISAKNSSETAENDSIDGKKIENIIQPIREDDFDPFEGLSKLEVASNAYKFAT
ENDLKDYADIFFRAGILAFDGDIYPLTSDEQRAVKNEREHKWTSQPFPLYYMAVMCAMCAVVQGMDETVINGAQLYIIKE
FRLDLMKNSEWLIGTIVGAPYLCCCLIGCALTGPLNKLLGRRGVIFLSCVIVIAASLWQSFSKNWVQIFIARLFLGLGIG
PKSATVPVFSAECSPASIRGGLVMMWQMWTAFGIMLGFIVDVLFIPRGSLSESVAWRLMMGSTCVVPVFICIQIYLIPES
PSWYLGKNKVKQAYESLCRYRSHKILAARDLYYMSQLKAISETRHPDNLLLSLFKEARNRRALVASQILMFLQQFCGVNI
IAYFSSKIFIDSGFSEKSSILASMGFGILNFIFAIPAVFTIDTFGRRALTLFTLPFLAIVLLFTGFSFWIPDKNARLGCV
TSGIYLYAIFYSPGMGPVPFTYSAEAFPSYVRDVGMSLATITLWGFNFLLSATWPPLLRVFKPQGAFGYYAAWNVIGFVL
VFFFVPETKALTLEELDSVFSTSTKTFINHQLTNIPSFLRKTKNNNNGQASYP

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane