Protein

MCA_00926_1

Length
311 amino acids


Gene name: GCY1

Description: Glycerol 2-dehydrogenase (NADP(+))

Browser: contigA:2922772-2923708-

RNA-seq: read pairs 11931, FPKM 472.5, percentile rank 94.0% (100% = highest expression)

Protein function

Annotation:GCY1Glycerol 2-dehydrogenase (NADP(+))
KEGG:K18097GCY1 glycerol 2-dehydrogenase (NADP+) [EC:1.1.1.156]
EGGNOG:0PFT7FG08941.1)-reductase
SGD closest match:S000005646GCY1Glycerol 2-dehydrogenase (NADP(+))
CGD closest match:CAL0000178894orf19.6758Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_05402_176.87%3074e-176MIA_05402_1
A0A167CS02_9ASCO65.35%3035e-145Glycerol 2-dehydrogenase (NADP(+)) GCY1 OS=Sugiyamaella lignohabitans GN=GCY1 PE=4 SV=1
A0A0J9XG62_GEOCN63.40%3061e-137Similar to Saccharomyces cerevisiae YOR120W GCY1 Glycerol dehydrogenase, involved in an alternative pathway for glycerol catabolism used under microaerobic conditions OS=Geotrichum candidum GN=BN980_GECA14s02529g PE=4 SV=1
Q6CDR7_YARLI56.48%3016e-114YALI0B21780p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B21780g PE=4 SV=1
UniRef50_A0A093V7I955.92%3041e-108Glycerol 2-dehydrogenase (NADP(+)) n=4 Tax=Eurotiales TaxID=5042 RepID=A0A093V7I9_TALMA
A0A1E3PE97_9ASCO52.30%3049e-100Aldo-keto reductase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48071 PE=4 SV=1
A0A1E4THU5_9ASCO50.34%2988e-97Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57596 PE=4 SV=1
GCY1_YEAST48.00%3004e-88Glycerol 2-dehydrogenase (NADP(+)) OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCY1 PE=1 SV=1
Q5ADT3_CANAL44.08%3046e-79Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6758 PE=4 SV=1
A0A060T5D7_BLAAD41.67%3003e-72ARAD1B10230p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10230g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0821

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 311

Detailed signature matches

    1. PR00069 (ALDKETRDTASE)
    1. SSF51430 (NAD(P)-li...)
    2. cd06660 (Aldo_ket_red)
    3. PF00248 (Aldo_ket_red)
    1. PS00062 (ALDOKETO_R...)

Residue annotation

  1. active site cd06660
  2. catalytic tetrad c...

Protein sequence

>MCA_00926_1
MSSPIPTVKLNTGAEIPVIGLGTWQSDKGLVRDAVFYALTETPIRHIDAAYVYLNEEEVGEGIQAAIDTGKVKRSDIFVT
TKVFPTFHNRVEESLNASLKNLKLDYVDLLLIHWPVGFNPKGNHPLFPKREDKSMDLDPTFSVLKTWKQFEKVYKSGKAK
AIGVSNFSVPVLTELLESDIEVVPAVNQIENHPFLPGKEIVDFCAKKGIIIEAYSPLGSTGAPLIENEVVTKLAEKYNTT
PATILISWHVNQGRVVLPKSTNPSRIKSNAEWVKIDEEDLKTLDGLSEKFGLKRVVKPNWGADLKFPDYHL

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.