Protein

MCA_00912_1

Length
1,555 amino acids


Browser: contigA:2873867-2878605-

RNA-seq: read pairs 2328, FPKM 18.5, percentile rank 39.3% (100% = highest expression)

Protein function

KEGG:K10661MARCH6 E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
EGGNOG:0PHMDPGUG_02476RING finger membrane protein
SGD closest match:S000001292SSM4ERAD-associated E3 ubiquitin-protein ligase DOA10
CGD closest match:CAL0000173927orf19.5175E3 ubiquitin-protein ligase

Protein alignments

%idAln lengthE-value
MIA_06233_140.57%5941e-109MIA_06233_1
A0A167ETJ3_9ASCO39.90%3912e-73E3 ubiquitin-protein ligase SSM4 OS=Sugiyamaella lignohabitans GN=SSM4 PE=4 SV=1
UniRef50_A0A167ETJ339.90%3915e-70E3 ubiquitin-protein ligase SSM4 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167ETJ3_9ASCO
A0A060SZ77_BLAAD37.47%3872e-64ARAD1C03058p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C03058g PE=4 SV=1
A0A1E3PRJ5_9ASCO38.46%4166e-63Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81133 PE=4 SV=1
A0A0J9XC64_GEOCN36.00%3752e-56Similar to Saccharomyces cerevisiae YIL030C DOA10 Ubiquitin-protein ligase involved in ER-associated protein degradation OS=Geotrichum candidum GN=BN980_GECA07s04542g PE=4 SV=1
A0A1D8PR66_CANAL31.41%3988e-38E3 ubiquitin-protein ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5175 PE=4 SV=1
Q6C145_YARLI30.45%4041e-36YALI0F19360p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F19360g PE=4 SV=1
A0A1E4TDI0_9ASCO33.43%3472e-31Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_144289 PE=4 SV=1
DOA10_YEAST30.52%3442e-30ERAD-associated E3 ubiquitin-protein ligase DOA10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSM4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0306

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1555

Detailed signature matches

    1. PF12906 (RINGv)
    2. SM00744 (ringv_2)
    3. PS51292 (ZF_RING_CH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF57850 (RING/U-box)
  2. TRANSMEMBRANE (Tran...)
  3. cd16702 (RING_CH-C4...)
  4. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...

Protein sequence

>MCA_00912_1
MSDDDQVCRICRSEATPNEPLFHPCKCSGSIRYVHQDCLKEWIEKSNKPPICDLCGYKFTFTKIYSQDLPQDSSDLLIRA
ISLFFKKLFYKHIPAFIKVITGIILWLHFPLILKEMLSLSLHLSDTLIINPRPPEFRTRPYNLPLVAYHESQVSFSSSIN
NMLPIFVAFFDSAIYYLSEHSFFSPVWAKLYSHTISSTLPIKQITSSQYLNILLNPLFTKKNYTHFLEGIAILSGYVLVY
LAVSLLKWSLQTELDRIIQNNDTTLSKFLGVDKLENEFHMERLNEILKTTLAAKRPADALRPQFQAQPPIESSDEEENEN
EETGDEISDTEADDNLLRLANIQRRHVFLRDLPEDEIDYSPLSREAKIALDYLRRIDYQGEITIEALQSVDPLEPFDFET
DVNYLKTVAKNQEPIHQPRRLEQRPNEELPIQFGNRHRRDEIAFQFGQNNQEGNGFHWGAIEDADDIFNHQQRMDNNNIP
NLGRLRNNNDNDFAANRNENLLDQIIQAQLAADRNENPLNANAAAVAAALDEEEEEEPLELNEIRDIIALLGINGSFVNL
ISKLMVAVCFSVVLNTGFVCLPYLIGGCLLSGLGFLLVASLEYLIYWGNKLADYILAFFCSIASAVLSSQTQKFQALRQS
FLLDAKTTQLHFSLLWKFLRISVYPHSQGPYMIGFLVSLGVAAVITIGYFMAYHYPRFATTLRGKKLEIQLIKNLRIVGL
GVKIILITGIEMIIFPMACGTLLVLALLPLHPTATVMDVANFAISNSRIFPLLVWFLGTLYMIKFAVYVNMCRGILRPGV
LYFIKDPNDPNLHPIGDIIQRTLTFQLGRIGISAIAYFILIVVCIGSVVWSMRYIFHASVIPFQLSDLSGTIPLFITIPL
STIFLLPFNLVFKHFKPAVIIKRAWTAVFRRCCHSLRLSSFLLNSPVPKERGTVHYGSFYAWLTNVQPDYSSPKTEEDLA
NIKPNEAMFVLDGHFVRAPNSDTSAHKNLKLFIPVNKDDERIDGKTDEQEEEETKKLIEQRALANGEEVKHEGPYRMTNY
FVVYRPPHFRMRVFGFFMFIWGFSFLMVYWVTAVPVLLGSKYVDFAIYLSSKSLSKPLEIPENTVNTPLQFLLGFPSIIL
ITQLIFEHETIGKMFNTFKTLGLRGFSDVLLIPYKFHHNLLLSWSKVIASYASIFYFYLLVCPVWIAFPTAYYFADVVQY
FFSVAMSPFINYSVLDAVTASYESGNATLALNSTSSSSSTGALLLAHVISGTQNSTTAVEAIQKYSSFLKYSAFPIHPIV
YDKHFEFSVFQLSVFTGTIALFYFFLSITCSSVSPFFSKFMRNVFTNERQVRQVANYMELMQPETLYDMLVADKLIQPGE
PIPVRVQYTLLNPNVKYALIKHTVPCVLYGALNLIIFEFIRIIFYLLMIFFTPGRFDNLSIPFLSHFWHFNPIYTAYFSV
MSLIGSKRLNNFISQSSSSSSLSSSSSSSFWSQLPSKEVQPSQFYFHHLFKFGSTKPTVLFTSYLILPFIAVLIIKLIIT
LLYQELRDEEFLIGEVLENLPTENNNNKEEEEVKI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

None predicted.