Protein
MCA_00870_1
Length
1,029 amino acids
Gene name: BUB1
Description: Checkpoint serine/threonine-protein kinase Bub1, in S. cerevisiae involved in the cell cycle checkpoint into anaphase.
Browser: contigA:2743901-2747056+
RNA-seq: read pairs 1191, FPKM 14.3, percentile rank 32.9% (100% = highest expression)
Protein function
| Annotation: | BUB1 | Checkpoint serine/threonine-protein kinase Bub1, in S. cerevisiae involved in the cell cycle checkpoint into anaphase. | |
|---|---|---|---|
| KEGG: | K02178 | BUB1 | checkpoint serine/threonine-protein kinase [EC:2.7.11.1] |
| EGGNOG: | 0PFEY | FG01347.1 | Checkpoint protein kinase |
| SGD closest match: | S000003420 | BUB1 | Checkpoint serine/threonine-protein kinase BUB1 |
| CGD closest match: | CAL0000187122 | BUB1 | Protein kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A060T6V5_BLAAD | 35.44% | 982 | 2e-163 | ARAD1B15136p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B15136g PE=4 SV=1 |
| UniRef50_A0A060T6V5 | 35.44% | 982 | 6e-160 | ARAD1B15136p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T6V5_BLAAD |
| MIA_05381_1 | 50.44% | 452 | 2e-118 | MIA_05381_1 |
| A0A0J9XJ62_GEOCN | 49.77% | 434 | 9e-122 | Similar to Saccharomyces cerevisiae YJL013C MAD3 Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly OS=Geotrichum candidum GN=BN980_GECA20s00670g PE=4 SV=1 |
| A0A1E3PNB4_9ASCO | 40.66% | 455 | 4e-88 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_76977 PE=4 SV=1 |
| A0A167DVT8_9ASCO | 51.74% | 317 | 4e-86 | Mad3p OS=Sugiyamaella lignohabitans GN=MAD3 PE=4 SV=1 |
| A0A1E4TBE6_9ASCO | 38.78% | 441 | 7e-76 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28450 PE=4 SV=1 |
| Q6CDK8_YARLI | 37.76% | 429 | 8e-76 | YALI0B23166p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B23166g PE=4 SV=1 |
| BUB1_YEAST | 36.24% | 356 | 6e-65 | Checkpoint serine/threonine-protein kinase BUB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUB1 PE=1 SV=2 |
| A0A1D8PLR1_CANAL | 37.72% | 334 | 3e-58 | Protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BUB1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0019
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
100
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400
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1029
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
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mobidb-lite (disord...)
Protein sequence
>MCA_00870_1 MSSPQQNQDNSNNIIQFDILECQKENIQPLMEGRSASALARAFAIPPAASPEIQEELTRKRDEFEDRIARSTAELDDPIE PYLEYISWINDTFPQGGNNPTNGIVQVLERCTSEFRDAPYYKDDPRYLKVWLRYITFSDSPREIFLYLARKEIGKNLASF YEEYAKYLEVNGLRRQAKETYEIGIELMARPLERLRRHYLEFCQRLEANPIDPDEPESSSGLQMVRPALAVKDSSTSEPV FEQTSTSTRSSIKEGFGGGLLSSKKKLAVYTDPDDQHSGSSTIPSAGGWDTLDSISSRRKENVIKASPWVGQTIKSAKPV NSNKQNKIPIFRDSSSGNNGYNQPVPVPGRRNEIIAVALEFLHDEYGEEYCLEEVLARARGLLHKSYPRDEEEKPAESQE NKKINDNTTKPISISSAESPVRRPPSPTMTMHTKAATDEVYEMFNQPIKPTNDDSFEEDEDYDDIYEDEDGYTKTGMTSS NNNNLGMENLRSCTENLNITNGSNENIDAKSYFNQNDENLPMNLENNDSVLGSHIDKPQQQHLHKPHGNLPAMTPIVERT ENISEYENTPSKPKVLRKPRTDVLIPKQICDPTLDADKNLILKNAYPFLNSLQTLHLHTRIKLNKGKKLKSDFLQPYELK YKTKGKDNKKKVKTPPPVLIELPRTNSNQGNRMYGIIEMIGTGGFGSVYLIESENGEHLACKIEDIPSIWEYYIICRLHY MLSSDPLATPSVLNSVINISDQYIFTDESLMIMDYIESQCTILDVANLARNEAAEGSSGGSNTIAGNSDGGVNETLAIFI VVELIRVIEAIHRHGIIHCDLKPENVMMRFKCYNHKTKAQNQNTDAWSEQYKADGSNGWKEKGIVLIDFGRSIDFNDPIY DTKTTRFKATWNPDAQDCVEVQKRLPWTFQVDYHGVASIAYLLLFGKFIEITTRKNNKTGAYEASIVGSIKRYWQQKLWT RLFHILLNSYSYSNNGENWPITDQLAQIRGEFEEYLEQTTGIINNNSASVHDQQSLKSCICHIEQKLSK
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
Cellular Component
None predicted.