Protein
MCA_00869_1
Length
573 amino acids
Gene name: ADE2
Description: Phosphoribosylaminoimidazole carboxylase
Browser: contigA:2741845-2743567-
RNA-seq: read pairs 3764, FPKM 81.0, percentile rank 75.5% (100% = highest expression)
Protein function
Annotation: | ADE2 | Phosphoribosylaminoimidazole carboxylase | |
---|---|---|---|
KEGG: | K11808 | ADE2 | phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21] |
EGGNOG: | 0PH6H | ADE2 | phosphoribosyl-aminoimidazole carboxylase |
SGD closest match: | S000005654 | ADE2 | Phosphoribosylaminoimidazole carboxylase |
CGD closest match: | CAL0000185210 | ADE2 | Phosphoribosylaminoimidazole carboxylase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_06069_1 | 74.17% | 573 | 0.0 | MIA_06069_1 |
A0A0J9XJV8_GEOCN | 74.87% | 573 | 0.0 | Similar to Saccharomyces cerevisiae YOR128C ADE2 Phosphoribosylaminoimidazole carboxylase OS=Geotrichum candidum GN=BN980_GECA20s00659g PE=3 SV=1 |
A0A1E3PGQ0_9ASCO | 70.86% | 573 | 0.0 | Putative phosphoribosylaminoimidazole carboxylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47592 PE=3 SV=1 |
A0A167DVU6_9ASCO | 68.70% | 575 | 0.0 | Phosphoribosylaminoimidazole carboxylase ADE2 OS=Sugiyamaella lignohabitans GN=ADE2 PE=3 SV=1 |
I7IIC5_BLAAD | 68.11% | 577 | 0.0 | ARAD1B15158p OS=Blastobotrys adeninivorans GN=AADE2 PE=3 SV=1 |
PUR6_CANAL | 64.00% | 575 | 0.0 | Phosphoribosylaminoimidazole carboxylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADE2 PE=3 SV=2 |
UniRef50_O74197 | 61.53% | 577 | 0.0 | Phosphoribosylaminoimidazole carboxylase n=206 Tax=Fungi TaxID=4751 RepID=PUR6_CANGA |
PUR6_YEAST | 61.28% | 576 | 0.0 | Phosphoribosylaminoimidazole carboxylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADE2 PE=1 SV=1 |
Q6CDK7_YARLI | 61.85% | 574 | 0.0 | YALI0B23188p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B23188g PE=3 SV=1 |
A0A1E4TBC6_9ASCO | 57.02% | 563 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_133364 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0766
Predicted cleavage: 18
Protein family membership
Domains and repeats
-
Domain
-
Domain
-
Domain
-
Domain
1
100
200
300
400
500
573
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
SSF56059 (Glutathio...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_00869_1 MDSKVLGILGGGQLGRMMVEAANRLNIKTVILDGENSPAKQINALTEHVNGSFTDAASIKKLASKCDVLTIEIEHVNANI LEEIEAETKVKVHPSPKIIKLIQDKYLQKIHLIENKIATPEIMVVEDENQVSSLQKIGDAFGYPFMLKSRTNAYDGRGNY VVKSKDDFETALTTLKGLPLYAEKFAEFTHELAVMIVVALDGTVYSYPTVETVQKNNICERVFAPARIQDSIKIKAQFLA ENAVKCLQTIDGKTVTGAGIYGVEMFLLKDGSIYLNEIAPRPHNSGHYTLDGCVTSQFESHIRAVTGLPLPKNFATMTTP STNVIMLNILGAEEANGELEYCKRSLNVPGAIIHLYGKSTRPNRKMGHINIVAPSMSQAEANLARVLGEEAQSSTSSQEQ GPAGTSSSPLVGVIMGSDSDLPVMSVGCNILKKFGVPFEVKIVSAHRTPYRMTKYATEAASRGLKAIIAGAGGAAHLPGM VAAMTTLPVIGVPVKGSTLDGVDSLHSIVQMPRGVPVATVAINNATNAALLAIRILGVFDPEYHNKLEDYHNSMESEVLG KTERLESVGYEKY
GO term prediction
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Molecular Function
GO:0003824 catalytic activity
GO:0004638 phosphoribosylaminoimidazole carboxylase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Cellular Component
None predicted.