Protein

MCA_00795_1

Length
514 amino acids

Gene name: SRP54

Description: Signal recognition particle 54 kDa protein homolog

Browser: contigA:2475191-2476736+

RNA-seq: read pairs 3311, FPKM 79.4, percentile rank 75.1% (100% = highest expression)

Protein function

Annotation:SRP54Signal recognition particle 54 kDa protein homolog
KEGG:K03106SRP54 signal recognition particle subunit SRP54 [EC:3.6.5.4]
EGGNOG:0PH16SRP54signal recognition particle
SGD closest match:S000006292SRP54Signal recognition particle subunit SRP54
CGD closest match:CAL0000195229SRP54Signal recognition particle 54 kDa protein

Protein alignments

%idAln lengthE-value
MIA_00999_181.94%4540.0MIA_00999_1
A0A060TBW3_BLAAD73.44%4480.0Signal recognition particle 54 kDa protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35134g PE=3 SV=1
A0A0J9X8L1_GEOCN71.71%4560.0Signal recognition particle 54 kDa protein OS=Geotrichum candidum GN=BN980_GECA05s02661g PE=3 SV=1
A0A167F2J5_9ASCO71.33%4290.0Signal recognition particle 54 kDa protein OS=Sugiyamaella lignohabitans GN=SRP54 PE=3 SV=1
SRP54_YARLI67.32%4560.0Signal recognition particle 54 kDa protein homolog OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SRP54 PE=3 SV=2
UniRef50_A0A167NG2065.56%4500.0Signal recognition particle protein srp54 n=2 Tax=Sordariomycetes TaxID=147550 RepID=A0A167NG20_9PEZI
A0A1E4TEF3_9ASCO63.50%4740.0Signal recognition particle 54 kDa protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31167 PE=3 SV=1
SRP54_YEAST64.61%4380.0Signal recognition particle subunit SRP54 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRP54 PE=1 SV=2
A0A1E3PLZ8_9ASCO64.64%4270.0Signal recognition particle 54 kDa protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82199 PE=3 SV=1
Q5A885_CANAL60.42%4750.0Signal recognition particle 54 kDa protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SRP54 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5376

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 514

Detailed signature matches

  1. Family IPR022941
    Signal recognition particle, SRP54 subunit
    1. MF_00306 (SRP54)
  2. Family IPR006325
    Signal recognition particle, SRP54 subunit, eukaryotic
    1. TIGR01425
  3. Domain IPR013822
    Signal recognition particle, SRP54 subunit, helical bundle
    1. SM00963 (SRP54_N_2)
    2. SSF47364 (Domain of...)
    3. PF02881 (SRP54_N)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  6. Domain IPR000897
    Signal recognition particle, SRP54 subunit, GTPase domain
    1. PS00300 (SRP54)
    2. SM00962 (SRP54_3)
    3. PF00448 (SRP54)
  7. Domain IPR004125
    Signal recognition particle, SRP54 subunit, M-domain
    1. PF02978 (SRP_SPB)
    2. G3DSA:1.10.26...
    3. SSF47446 (Signal pe...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.12...
  2. G3DSA:3.40.50...

Protein sequence

>MCA_00795_1
MVLADLGRKINGALNDLTKSSVVDESALDLLLKEISSALLESDVNVDLVTRLRNNVKSKVNLKDDTPGVNKKRLIQKTLF
DELTSLVDGKQEPFRPKKGKSNVIMFVGLQGAGKTTTCTKLAVYYQRRGFKTGLVCADTFRAGAFDQLKQNATKAKIPYY
GSYTEMDPVKVSKEGVDKFKKEKFDIIIVDTSGRHRQEEALFQEMIEIGQAVKPNQTIMVMDASIGQAAEAQSKAFKESS
NFGAIILTKMDGHAKGGGAISAVAATHTPIVFIGTGEHIHDLEPFSPQSFISQLLGIGDIGSFLDHVQGLQLDSKDTINN
LQKGIFTFHNLRDQMTSLTKMGPLNKVAGMIPGMSQLANSMDEKESTERIKAMVCIIDSMTPKEVNSDGKIFKEEPSRIL
RVARGSGRSVREVEDVLAQQQMMAKMAKNIGGKNGLLNQMQNPEAARNNPRIAQAQRKMAQMMGGAGGAGGMPDMSALAN
MMGGAGGAGGMPDMSAMMNNPMVKNMMKQFGMGM

GO term prediction

Biological Process

GO:0006614 SRP-dependent cotranslational protein targeting to membrane

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding

Cellular Component

GO:0048500 signal recognition particle