Protein

MCA_00786_1

Length
234 amino acids

Gene name: PIS1

Description: CDP-diacylglycerol--inositol 3-phosphatidyltransferase

Browser: contigA:2440417-2441122+

RNA-seq: read pairs 2498, FPKM 131.3, percentile rank 83.0% (100% = highest expression)

Protein function

Annotation:PIS1CDP-diacylglycerol--inositol 3-phosphatidyltransferase
KEGG:K00999CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]
EGGNOG:0PI51PIS1CDP-diacylglycerol-inositol 3-phosphatidyltransferase
SGD closest match:S000006317PIS1CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CGD closest match:CAL0000175849orf19.6860CDP-diacylglycerol--inositol 3-phosphatidyltransferase

Protein alignments

%idAln lengthE-value
MIA_01015_190.95%2322e-160MIA_01015_1
A0A0J9X7R5_GEOCN86.75%2341e-156CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Geotrichum candidum GN=BN980_GECA05s02617g PE=3 SV=1
A0A060TIJ1_BLAAD75.89%2242e-125CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D38896g PE=3 SV=1
A0A1E3PIH7_9ASCO76.50%2178e-121CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47280 PE=3 SV=1
A0A1E4TK69_9ASCO69.81%2122e-105CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82729 PE=3 SV=1
Q6C104_YARLI68.78%2219e-105CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F20328g PE=3 SV=1
UniRef50_M7NUR465.16%2218e-99CDP-diacylglycerol--inositol 3-phosphatidyltransferase n=5 Tax=Fungi TaxID=4751 RepID=M7NUR4_PNEMU
PIS_YEAST47.79%2261e-67CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PIS1 PE=1 SV=1
Q59RA2_CANAL48.15%2169e-67CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6860 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3235

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

  1. Family IPR000462
    CDP-alcohol phosphatidyltransferase
    1. PS00379 (CDP_ALCOHO...)
    2. PF01066 (CDP-OH_P_t...)
  2. Family IPR014387
    CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote
    1. PIRSF000848 (CDP_di...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_00786_1
MSWTKAPHGSVITTKDIFLFIPNLIGYSRVLFALASLFFMQWHPKYCTVLYCLSCLLDALDGVAARRYGQTSRFGAILDM
VTDRCTTSSLICYLCVAYPKYAIIFQLLVSLDLASHYMHMYAMLTSGSSSHKKVGKESWILNQYYTNNKVLFTFCAFNEL
FFVGLYLYSFPLKTPPNLGYIQGIPLSYPTIILIVTFPLWLGKQIINVIQMYRAAVSLAETDVEERRLAAAKEK

GO term prediction

Biological Process

GO:0008654 phospholipid biosynthetic process

Molecular Function

GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Cellular Component

GO:0016020 membrane