Protein

MCA_00784_1

Length
377 amino acids

Gene name: URH1

Description: Uridine nucleosidase

Browser: contigA:2435213-2436347-

RNA-seq: read pairs 552, FPKM 18.0, percentile rank 38.6% (100% = highest expression)

Protein function

Annotation:URH1Uridine nucleosidase
KEGG:K01240URH1 uridine nucleosidase [EC:3.2.2.3]
EGGNOG:0PJG7URH1uridine nucleosidase
SGD closest match:S000002808URH1Uridine nucleosidase
CGD closest match:CAL0000198549orf19.1888Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase

Protein alignments

%idAln lengthE-value
MIA_01020_152.56%3901e-117MIA_01020_1
A0A060TCG7_BLAAD49.47%3749e-112ARAD1D36036p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36036g PE=4 SV=1
A0A0J9XAK8_GEOCN52.96%3721e-110Similar to Saccharomyces cerevisiae YDR400W URH1 Uridine nucleosidase OS=Geotrichum candidum GN=BN980_GECA07s00593g PE=4 SV=1
UniRef50_A0A0J9XAK852.96%3723e-107Similar to Saccharomyces cerevisiae YDR400W URH1 Uridine nucleosidase n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XAK8_GEOCN
A0A167EF28_9ASCO46.74%3832e-103Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase OS=Sugiyamaella lignohabitans GN=URH1 PE=4 SV=1
A0A1E3PFI1_9ASCO47.04%3723e-103Inosine/uridine-preferring nucleoside hydrolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52497 PE=4 SV=1
Q6C307_YARLI38.60%3993e-79YALI0F03597p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F03597g PE=4 SV=1
A0A1D8PI06_CANAL35.20%3751e-66Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1888 PE=4 SV=1
URH1_YEAST38.34%3861e-63Uridine nucleosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=URH1 PE=1 SV=2
A0A1E4THV1_9ASCO25.89%2822e-11Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31977 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0241

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 377

Detailed signature matches

  1. Domain IPR001910
    Inosine/uridine-preferring nucleoside hydrolase domain
    1. PF01156 (IU_nuc_hydro)
    2. G3DSA:3.90.24...
    3. SSF53590 (Nucleosid...)
  2. SITE IPR015910
    Inosine/uridine-preferring nucleoside hydrolase, conserved site
    1. PS01247 (IUNH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd02651 (nuc_hydro_...)

Residue annotation

  1. active site cd02651
  2. tetramer interface...

Protein sequence

>MCA_00784_1
MGKLPLWIDCDPGHDDAIAILLGSNLPYFNLVGISTVHGNAPLSHTTENALSLLEAFHIDPSVDVYPGADKPIKRPLEVA
PSIHGESGLDGTKLLPKPVKKPVFYKPNGERYIGELSSIGDGSPDKPNVPRFNSAAYALAEAVKKYPGELLVVATGTLTN
IADFIAQSPELVPKIKALSIMGGGFKLGNWTKFAEFNIWCDPEAAQTVLASDKELSKKTFLVPLDMTHQAIATKEIIEQV
LNEKKSEGKDTSKSENTPLDGKRHYVRRMLYELLLFFAHTYETTFGDQFKLGPPVHDPLAVAALIPSFVAPVFPNVPELN
MVVSKYKLDVVLEGERVGQTVEVAKDNEYGVQVVEGMNIDSFWQIVLESLNNLDAKA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds

Cellular Component

None predicted.