Protein
MCA_00775_1
Length
1,394 amino acids
Browser: contigA:2415081-2419266+
RNA-seq: read pairs 1901, FPKM 16.8, percentile rank 36.7% (100% = highest expression)
Protein function
| KEGG: | K12385 | NPC1 | Niemann-Pick C1 protein |
|---|---|---|---|
| EGGNOG: | 0PFV1 | FG09254.1 | Patched sphingolipid transporter (Ncr1) |
| SGD closest match: | S000005927 | NCR1 | Niemann-Pick type C-related protein 1 |
| CGD closest match: | CAL0000182780 | NCR1 | Sphingolipid transporter |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01027_1 | 68.73% | 1343 | 0.0 | MIA_01027_1 |
| A0A0J9XDS8_GEOCN | 62.71% | 1357 | 0.0 | Similar to Saccharomyces cerevisiae YPL006W NCR1 Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway OS=Geotrichum candidum GN=BN980_GECA11s01022g PE=4 SV=1 |
| A0A060TF82_BLAAD | 56.58% | 1345 | 0.0 | ARAD1D13640p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D13640g PE=4 SV=1 |
| A0A1E3PLV4_9ASCO | 53.04% | 1348 | 0.0 | Patched sphingolipid transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82768 PE=4 SV=1 |
| UniRef50_A0A1D2VR30 | 50.18% | 1375 | 0.0 | Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway n=1 Tax=Ascoidea rubescens DSM 1968 TaxID=1344418 RepID=A0A1D2VR30_9ASCO |
| Q6CBA1_YARLI | 48.17% | 1368 | 0.0 | YALI0C20757p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C20757g PE=4 SV=1 |
| A0A167EDJ4_9ASCO | 52.87% | 1203 | 0.0 | Ncr1p OS=Sugiyamaella lignohabitans GN=NCR1 PE=4 SV=1 |
| A0A1D8PFW9_CANAL | 46.07% | 968 | 0.0 | Sphingolipid transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NCR1 PE=4 SV=1 |
| A0A1E4TCQ4_9ASCO | 43.07% | 1003 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58439 PE=4 SV=1 |
| NPC1_YEAST | 41.77% | 948 | 0.0 | Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NCR1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4182
Protein family membership
- Protein patched/dispatched (IPR003392)
Domains and repeats
-
Domain
1
200
400
600
800
1000
1200
1394
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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-
NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SSF82866 (Multidrug...)
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-
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_00775_1 MTTLLSSSISLRSFQRCKIISILLLLSLLFSQQANASGDSIVTPTHAPGVCAIYSSCGKQSFFGPELPCPANVPAVDPNA ETRKALIDVCGEEWSEGPICCDLGQINTLKTNLKKAENLISSCPACKDNFFQFFCRFTCSPDQSLFVNITETAISNTKKE IVAELDHFVDPVFAKGFYDSCKDVKFGATNGYAMDLLGGGAKNYTEFLKFLGDKKPLLGGSPFQMDFPWDHLPDGFKPNT GPIRRCNDTDEKYRCACNDCPGSCPTLPELKEERVCKVGMISCFSFAVIIIYSSILFIILLAYSGYIAYKFNKQRSTETM RLLHDDNYDEYEEDEEEDDEDYLHDRPVGSQSVLSRYRNSKVYQRLLRFKKKVYPRRFLRKFRLSNSNYLRGQYQLNTLI QSWFTKAAFIFASFPGTVIAISLFVVFVLSLGIFHLELILSPVKLWVSSSSTEYQEKMFYDENFGPFYRSEQVYLVNETG PVLSWDTLNWWFAAEQEINNLASPSGVKLSDLCVKPFGDACVIQSMTQYFGGNINRLSENSWQGQIASCAATPVNCLPPF NQPLKKNLLFGGYDEKTQSVLSSKALVATWVLQNADEGTELADKAADWEESLRQVLFRLQDEAKERGLRISFNTETSLQK ELNKSSNTDARIIFLSYVFMFIYASVALGGVIPGFGRNSFVKSKFSLGLFGIFVVLLSVAASVGLFSMLGIKVTLIIAEV IPFLVLAVGVDNIFLLTHELENVNASHPNDSVEERVSRAVGHIGPSILLSAFCETLTFALGATVSMPAVRNFAIYSAGAV FINFLLQMTMFVSALTLDQKRLEENRYDLFVWIKAPLPKGSDSARDETSPFSSLSVRALASPGVFEKFTEPTISKVIRRH YAPYILNRKVKPVIIAVFFGIFTVALALLPYISLGLDQRVAIPSDSYLINYFNDMYDYFNSGPPVYFVVKNLDVTQRESQ QALCGRFTTCDDFSLANIIEQERKRSELSYLQDPPAVWIDDFFTWLNPSLDECCLVKIPQGQQVNPGFLGLEPTKFNGTI DFCGPYDNPHYCQSCYADHKPEWDPQMHGLPEGDEFMAYFNQWIESPSDPCPLGGKAPYGAEIAVDKDTNTIKASKFRSM HVPLRSQEDFIESYAQARRIAHDIHQSTGIDVYPYSSFYIFFAQYKTIIADTLSLIGTSLSLIFVVASILLGSIRTSFAL VLTVIMIVADIAGVMALWSISLNAVSLVNLVICVGIGVEFCAHIARAFTFCPKSQYITAVESNDSDNVNNPAAYSHITHR NTYVPGPKQTRSFNSLVGVGGSVFGGIALTKFIGVSVLAFTHSKIFDIYYFRMWLSLVIIATLHGLVFLPVLLTYIGGGG YILDEGDEGLVGDLASRLYNPNRGDDSDIDDEFD
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
GO:0016021 integral component of membrane