Protein

MCA_00724_1

Length
1,056 amino acids

Gene name: PMT1

Description: Dolichyl-phosphate-mannose--protein mannosyltransferase 1; transfers mannose from dolichyl phosphate-D-mannose to protein serine and threonine residues

Browser: contigA:2259555-2262726+

RNA-seq: read pairs 8860, FPKM 103.6, percentile rank 79.4% (100% = highest expression)

Protein function

Annotation:PMT1Dolichyl-phosphate-mannose--protein mannosyltransferase 1; transfers mannose from dolichyl phosphate-D-mannose to protein serine and threonine residues
KEGG:K00728POMT dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
EGGNOG:0PFPSFG08935.1Mannosyltransferase
SGD closest match:S000002253PMT1Dolichyl-phosphate-mannose--protein mannosyltransferase 1
CGD closest match:CAL0000192847PMT1Dolichyl-phosphate-mannose--protein mannosyltransferase 1

Protein alignments

%idAln lengthE-value
A0A0J9XC46_GEOCN62.41%8140.0Similar to Saccharomyces cerevisiae YDL095W PMT1 Protein O-mannosyltransferase OS=Geotrichum candidum GN=BN980_GECA09s00648g PE=4 SV=1
UniRef50_A0A0J9XC4662.41%8140.0Similar to Saccharomyces cerevisiae YDL095W PMT1 Protein O-mannosyltransferase n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XC46_GEOCN
MIA_00211_163.14%8030.0MIA_00211_1
A0A060T6Y3_BLAAD60.77%8080.0ARAD1C24310p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C24310g PE=4 SV=1
A0A1E3PM27_9ASCO62.06%7170.0PMT-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45766 PE=4 SV=1
Q6C5U6_YARLI58.03%7910.0YALI0E15081p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E15081g PE=4 SV=1
A0A167BX15_9ASCO58.84%7240.0Dolichyl-phosphate-mannose-protein mannosyltransferase PMT1 OS=Sugiyamaella lignohabitans GN=PMT1 PE=4 SV=1
A0A1E4TM28_9ASCO48.77%7320.0Glycosyltransferase family 39 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56361 PE=4 SV=1
PMT1_CANAL44.98%8070.0Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT1 PE=2 SV=1
PMT1_YEAST45.97%7810.0Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0555

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 1000 1056

Detailed signature matches

  1. Domain IPR003342
    Glycosyl transferase family 39/83
    1. PF02366 (PMT)
  2. Domain IPR016093
    MIR motif
    1. PF02815 (MIR)
    2. PS50919 (MIR)
    3. SSF82109 (MIR domain)
    4. SM00472 (mir_2)
  3. Domain IPR032421
    Protein O-mannosyl-transferase, C-terminal four TM domain
    1. PF16192 (PMT_4TMC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:1.20.5....
  4. G3DSA:2.80.10.50
  5. NON_CYTOPLASM... (N...)
  6. TMhelix
  7. TRANSMEMBRANE (Tran...)
  8. mobidb-lite (disord...)

Protein sequence

>MCA_00724_1
MSKSHKGSKASGNNVKSEKLSNGPVSANDKSVDEIAKTLESNSSTTAPPPSQAYERSLNSTDYKFLTILTVFASYIRYYR
LWQPSSVVFDEVHFGGFARKYIIGRFFMDVHPPLAKMLYAVVAYLAGFDGEFEFKTIGLDYISNNVPYVAMRMLPATLGV
LTILLCYGTLRATGCHSITALFGSALLTVENTFVTESRYILLDSPLVFFIAITAYAFMKFQNYIPFQRDWYRYLFLTGLG
IGATVSSKWVGIFTIGWVGCMTVWQLWWILADLSVSPRDYTRQFVARVVCLIITPLTFYLAMFGLHFICLANTGDGASFL
SPEFQATLQHSPLKGNVPADVILGSKISIRHVNTQGGYLHSHNHMYPTGSKQQQVTLYPHRDTNNDWIVENVTYRADGWD
NIDPTFITDGMVIRLNHAVTHRRLHSHDVRPPVTEQDYQNEVSAYGYKGFEGDANDNFRVDIIKDKSAKGPARERLRTLE
TKFRLIHTTTGCVLFSHPVKLPKWGYEQQEVTCVKSGTLPNSIWMIEQNSHPKLTGPETEMITWKKPSFLAKVIELNKVM
WRVNAGLTDTHAWQSRPESWFILKRGINFWGKDHRHVYLIGNLPIYWSIAALVIGFTLFKLFEALRWQRGYKPFSGAAFK
TFDTGVTYFLLGWAFHYFPSFLMERQLFLHHYLASLYFGILAVTQAFEYLVFGLFGQKTLSVRKAKKPIYIGYIIMFGFF
SVCAAFFYWYSPLAYGTPWTKSACEKSKFMDMDFDCNLYLDKYEDYIKYDAENTGPAPSESLVTVTESADVPVESVESAQ
IPAAGQPQQEVVYVDENGEEIVGYNPADHPEHVIQEYPGEYAPGPEGAAEGVPEGDAGELGEDEEYDPYATDDIIYEDLQ
SQVEAETTDDVPSEKAGEAEQKVIKAEDKKEEVKEKIEDKKEEVKEKTEEVKEKVEEVKEKVEEKKAEVKQKVEEEKAEV
KQKVIKDEETASKKAAEKATEESDDEESDSDEEESDSESDEDDEEEEEEDKKKEDDDEEEEDSDDDEESDDDEESDDDEE
EEDEDSDDDSDDSDEE

GO term prediction

Biological Process

GO:0006493 protein O-linked glycosylation

Molecular Function

GO:0000030 mannosyltransferase activity

Cellular Component

GO:0016020 membrane