Protein

MCA_00717_1

Length
838 amino acids


Gene name: ABZ1

Description: Aminodeoxychorismate synthase; para-aminobenzoate (PABA) synthase; has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis

Browser: contigA:2241539-2244056-

RNA-seq: read pairs 1102, FPKM 16.2, percentile rank 35.8% (100% = highest expression)

Protein function

Annotation:ABZ1Aminodeoxychorismate synthase; para-aminobenzoate (PABA) synthase; has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis
KEGG:K13950pabAB para-aminobenzoate synthetase [EC:2.6.1.85]
EGGNOG:0PJCMPAB1Para-aminobenzoate synthase
SGD closest match:S000005316ABZ1Aminodeoxychorismate synthase
CGD closest match:CAL0000183785ABZ14-amino-4-deoxychorismate synthase

Protein alignments

%idAln lengthE-value
MIA_03281_161.84%8280.0MIA_03281_1
A0A0J9XDU5_GEOCN54.20%8450.0Similar to Saccharomyces cerevisiae YNR033W ABZ1 Para-aminobenzoate (PABA) synthase OS=Geotrichum candidum GN=BN980_GECA12s00978g PE=4 SV=1
UniRef50_A0A0J9XDU554.20%8450.0Similar to Saccharomyces cerevisiae YNR033W ABZ1 Para-aminobenzoate (PABA) synthase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDU5_GEOCN
A0A1E3PPS6_9ASCO48.90%8610.0Para-aminobenzoate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81914 PE=4 SV=1
A0A161HJB5_9ASCO48.48%8580.04-amino-4-deoxychorismate synthase OS=Sugiyamaella lignohabitans GN=ABZ1 PE=4 SV=1
Q6CHS7_YARLI47.31%8540.0YALI0A05379p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A05379g PE=4 SV=1
A0A060T378_BLAAD42.43%8320.0ARAD1C30338p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30338g PE=4 SV=1
A0A1D8PMB0_CANAL38.95%8731e-1734-amino-4-deoxychorismate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ABZ1 PE=4 SV=1
A0A1E4TEH5_9ASCO35.36%8371e-137Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1893 PE=4 SV=1
PABS_YEAST34.24%8828e-123Aminodeoxychorismate synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ABZ1 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0581

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 700 838

Detailed signature matches

    1. SSF52317 (Class I g...)
    1. PF00117 (GATase)
    2. PS51273 (GATASE_TYPE_1)
    1. SSF56322 (ADC synthase)
    1. PF04715 (Anth_synt_I_N)
    1. PF00425 (Chorismate...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00096 (GATASE)
  2. PR00097 (ANTSNTHASEII)
  3. PR00099 (CPSGATASE)
  4. cd01743 (GATase1_An...)

Residue annotation

  1. glutamine binding ...
  2. catalytic triad cd...

Protein sequence

>MCA_00717_1
MTMDQPERPSRILLIDSYDSFTLNLSSLIAEVTRAEVVTIHNDSVDPNTLIENYLKFFDAVVIGPGPGSPDIAEDVGVIP
HLLNLSTIENGLLPIFGVCLGFQSLVLSTSGKVIRLPEPNHGQVASIEHSGNDIFEGITENFDSVRYHSLHGIIPNRDSE
DTTTDEHIIPLAWTKDIHCEDKVLMAGKHSSKPFWGVQYHPESICSKHGGTVIQNFWKLAREWAQTNGRLTKIEDSDGSY
SNLLKLYSIKPHAFKTDISKEVSDESTFINAVNSRLEEVTYLSTNLTEIQREYETKISTNYATVLICEELHKSGQEFVLM
NSAANPGRWSIIGLIEPGKTICIKHYNEYDPDYVFVHPFEKDTKKRYASIPENEKRLKLGEGSNNGIWGFLSSYMSPKIE
RYKKSINIDGRLKSSGEYVVGMAPPGALFCGGLTGYLSYEAPQNLDSYPSKIKLQKLTASHTELNEPLRPYPDVNMVDIE
KCILLDSETGTAYVLSLVDKPLNQPPKWMQETCSLIESTLVKYLKGEDKLEIPNMCHELFKNVSADEEVKIEMPNKDHYI
DHIKKCQEELRAGNSYELCLTAQTKIILPEPIDSWDLYKILYKRNPAPYSCLFDFPEATLCGSSPERFMNWSGTTGKCQF
RPIKGTVKKGPHVTFESASAILNTPKERGENLMIVDLIRHDLNSLLSNVQVKKLMGVEEYKTVYQLVSVITGDLNLEANK
GYDTKSYSGFDVLIHSLPPGSMTGAPKIRSVEILRELEDWVPRGIYSGVSGYWSVLDEGDWSVIIRSAFRYKNEVSPNEP
NSQIWRIGAGGAITILSDPEDEWHEMSIKLESALQAFS

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009058 biosynthetic process

Molecular Function

None predicted.

Cellular Component

None predicted.