Protein

MCA_00707_1

Length
614 amino acids

Gene name: ALO1

Description: D-arabinono-1,4-lactone oxidase

Browser: contigA:2206933-2208778-

RNA-seq: read pairs 6056, FPKM 121.7, percentile rank 82.0% (100% = highest expression)

Protein function

Annotation:ALO1D-arabinono-1,4-lactone oxidase
KEGG:K00107ALO D-arabinono-1,4-lactone oxidase [EC:1.1.3.37]
EGGNOG:0PHKJALO1D-arabinono-1,4-lactone oxidase
SGD closest match:S000004551ALO1D-arabinono-1,4-lactone oxidase
CGD closest match:CAL0000174500ALO1D-arabinono-1,4-lactone oxidase

Protein alignments

%idAln lengthE-value
MIA_00197_163.82%5970.0MIA_00197_1
A0A0J9XI62_GEOCN61.78%5730.0Similar to Saccharomyces cerevisiae YML086C ALO1 D-Arabinono-1,4-lactone oxidase OS=Geotrichum candidum GN=BN980_GECA18s01187g PE=4 SV=1
ALO_YARLI55.12%5860.0D-arabinono-1,4-lactone oxidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ALO1 PE=3 SV=1
A0A1E3PSH0_9ASCO55.03%5760.0D-arabinono-1,4-lactone oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44892 PE=4 SV=1
A0A167EEP5_9ASCO49.14%5800.0D-arabinono-1,4-lactone oxidase OS=Sugiyamaella lignohabitans GN=ALO1 PE=4 SV=1
ALO_CANAL48.32%5960.0D-arabinono-1,4-lactone oxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ALO1 PE=3 SV=1
UniRef50_O9385248.32%5960.0D-arabinono-1,4-lactone oxidase n=28 Tax=Saccharomycetales TaxID=4892 RepID=ALO_CANAL
A0A060T4P9_BLAAD46.41%5710.0ARAD1A19404p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A19404g PE=4 SV=1
ALO_YEAST46.19%5782e-172D-arabinono-1,4-lactone oxidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ALO1 PE=1 SV=1
A0A1E4TFX5_9ASCO45.44%5705e-173Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57079 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3343

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 614

Detailed signature matches

  1. Family IPR010031
    L-gulonolactone/D-arabinono-1,4-lactone oxidase
    1. PIRSF000136 (LGO_GLO)
  2. Family IPR030654
    Sugar 1,4-lactone oxidase
    1. TIGR01678
  3. Domain IPR016167
    FAD-binding, type 2, subdomain 1
    1. G3DSA:3.30.43.10
  4. Domain IPR016166
    FAD-binding, type 2
    1. SSF56176 (FAD-bindi...)
    2. PS51387 (FAD_PCMH)
  5. Domain IPR006094
    FAD linked oxidase, N-terminal
    1. PF01565 (FAD_binding_4)
  6. Domain IPR016169
    CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
    1. G3DSA:3.30.46...
  7. Domain IPR007173
    D-arabinono-1,4-lactone oxidase
    1. PF04030 (ALO)
  8. Domain IPR016170
    Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain
    1. G3DSA:3.40.46...
  9. SITE IPR006093
    Oxygen oxidoreductase covalent FAD-binding site
    1. PS00862 (OX2_COVAL_FAD)

Protein sequence

>MCA_00707_1
MSRSSSDISSSRIDIASSVKSNDNGLSPELVSLVDQCEVKSKKYHRTWAGTFQCKPSRYFQPSTIEEIKAIVSLASKTKA
RIMAVGSGHSPSDLTMGHPAKSLPSTFSPSATGLNSWVSSEWYVNLDKFNKPIKLESYKNEPKETALYTDVTVEAGIRIY
QINEYLKENGLALQNLGSISEQSIAGIISTGTHGSSAYHGLVSQQIVDLTVLVASTGKLVKCSETENTDLFRAALLSLGK
IGLIVYATIRAIPKFTIHSVQEVIAFDKFLGEVPIDPSKPADDPVNQLWENFWTSSEYLRVWWYPYSNRCILWRANKSTA
PLSKPRESWYGTTLGRLFYQSLLWIAVKIWPSCTPMIEKFVFDKQYGLTETYRIPNELESSTTKADEAVQESVEGLNMDC
LFSQFVDEWGVPLKTGKETLFKLREKIFAAAKNGTYYVHVPIEVRCSNLTTVANVSDSPETTKMLISNAENSSDKPHVGA
IPGNSLAPFLNPAPNGIEYAAPIPGKVSNKNLTLYINATMYRPFGFNSPIDKWFREFEDIVDGAGGKPHWAKNFLGREEP
GYIAPTDGHMRGLSKQVDEWFGKDLKAWKDTRAKYDPENVFLSGETWAKVNGLL

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0003885 D-arabinono-1,4-lactone oxidase activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
GO:0050660 flavin adenine dinucleotide binding

Cellular Component

GO:0016020 membrane