Protein

MCA_00692_1

Length
645 amino acids


Gene name: SSA4A

Description: protein of the HSP70 family; has a role in SRP-dependent cotranslational protein-membrane targeting and translocation

Browser: contigA:2171985-2173923+

RNA-seq: read pairs 12192, FPKM 233.2, percentile rank 89.8% (100% = highest expression)

Protein function

Annotation:SSA4Aprotein of the HSP70 family; has a role in SRP-dependent cotranslational protein-membrane targeting and translocation
KEGG:K03283HSPA1_8 heat shock 70kDa protein 1/8
EGGNOG:0PFQWHSP70heat shock
SGD closest match:S000000905SSA4Heat shock protein SSA4
CGD closest match:CAL0000184706SSA1Heat shock protein SSA1

Protein alignments

%idAln lengthE-value
MIA_05468_190.18%6110.0MIA_05468_1
A0A0J9X850_GEOCN86.67%6450.0Similar to Saccharomyces cerevisiae YBL075C SSA3 ATPase involved in protein folding and the response to stress OS=Geotrichum candidum GN=BN980_GECA04s07732g PE=3 SV=1
A0A060TFE3_BLAAD87.70%6100.0ARAD1D14740p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14740g PE=3 SV=1
A0A167C832_9ASCO87.70%6100.0Hsp70 family ATPase SSA3 OS=Sugiyamaella lignohabitans GN=SSA3 PE=3 SV=1
Q6C0E9_YARLI86.99%6070.0YALI0F25289p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F25289g PE=3 SV=1
A0A1E3PCY5_9ASCO83.72%6450.0Heat shock protein 70 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44162 PE=3 SV=1
HSP71_CANAL86.51%6080.0Heat shock protein SSA1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SSA1 PE=1 SV=2
UniRef50_P4658782.66%6460.0Heat shock protein SSA2 n=714 Tax=Eukaryota TaxID=2759 RepID=HSP72_CANAL
A0A1E4TGS8_9ASCO82.07%6470.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2600 PE=3 SV=1
HSP74_YEAST79.69%6450.0Heat shock protein SSA4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSA4 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0452

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 645

Detailed signature matches

    1. PF00012 (HSP70)
    2. PR00301 (HEATSHOCK70)
    1. SSF100920 (Heat sho...)
    1. SSF100934 (Heat sho...)
    1. PS00297 (HSP70_1)
    2. PS01036 (HSP70_3)
    3. PS00329 (HSP70_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF53067 (Actin-lik...)
  2. cd10233 (HSPA1-2_6-...)
  3. mobidb-lite (disord...)

Residue annotation

  1. nucleotide binding...
  2. NEF/HSP70 interact...
  3. BAG/HSP70 interact...
  4. SBD interface cd10...

Protein sequence

>MCA_00692_1
MSKAVGIDLGTTYSCVAHFTNDRVEIIANDQGNRTTPSFVAFTDTERLLGDAAKNQAAMNPKNTVFDAKRLIGRKFDDPE
VQNDMKHFPFKVVNKGGKPAIEVEFKGETKVFQPEEISSMVLTKMKETAEAYLGGTVKDAVITVPAYFNDSQRQATKDAG
LIAGLNVLRIINEPTAAAIAYGLDKKSSGEKNVLIFDFGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDIDNKLVNHFI
QEFKRKNKKDLSGNQRALRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYSSITRARFEELCGDIFRSTLEPVEKVLR
DSKIDKSQVDDIVLVGGSTRIPRIQKLVSDFFNGKELSKSINPDEAVAYGAAVQAAILSGDTTNTKTQDILLLDVAPLSL
GIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVYEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDID
ANGILNVSAVEKGTGKSSKITITNDKGRLSKEEIERMVSEAEKYKEEDEKEAARIAAKNGVESYAYSLKNTINESGFKEK
VSESDREKLEKAINETIEWLDNNQTATTEEYEDKKKELESVSNPIMTSFYQGAGGAGGMPGGMPGGPGAAPGAGGSDGPT
VEEVD

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.