Protein

MCA_00660_1

Length
616 amino acids

Gene name: LCB4

Description: Sphinganine kinase LCB4

Browser: contigA:2063509-2065360-

RNA-seq: read pairs 1543, FPKM 30.9, percentile rank 53.6% (100% = highest expression)

Protein function

Annotation:LCB4Sphinganine kinase LCB4
KEGG:K04718SPHK sphingosine kinase [EC:2.7.1.91]
EGGNOG:0PI8CLCB4sphingoid long chain base kinase
SGD closest match:S000004250LCB5Sphingoid long chain base kinase 5
CGD closest match:CAL0000174172LCB4Sphinganine kinase

Protein alignments

%idAln lengthE-value
MIA_01408_148.74%5541e-171MIA_01408_1
A0A0J9X506_GEOCN40.81%5712e-131Similar to Saccharomyces cerevisiae YOR171C LCB4 Sphingoid long-chain base kinase OS=Geotrichum candidum GN=BN980_GECA02s08480g PE=4 SV=1
A0A170QYQ9_9ASCO47.96%4178e-133Sphinganine kinase LCB4 OS=Sugiyamaella lignohabitans GN=LCB4 PE=4 SV=1
UniRef50_A0A170QYQ947.96%4172e-129Sphinganine kinase LCB4 n=2 Tax=Trichomonascaceae TaxID=410830 RepID=A0A170QYQ9_9ASCO
A0A060TCW8_BLAAD40.00%4653e-115ARAD1B19030p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19030g PE=4 SV=1
W0TYP2_YARLI38.76%4673e-106YALI0B11154p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11154g PE=4 SV=1
Q5A3L3_CANAL38.23%4296e-92Sphinganine kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LCB4 PE=4 SV=1
LCB5_YEAST36.61%4482e-90Sphingoid long chain base kinase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LCB5 PE=1 SV=1
A0A1E3PQI3_9ASCO34.32%4407e-75Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39124 PE=4 SV=1
A0A1E4TKJ4_9ASCO31.52%4224e-62Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_84475 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0595

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 616

Detailed signature matches

  1. Domain IPR017438
    Inorganic polyphosphate/ATP-NAD kinase, domain 1
    1. G3DSA:3.40.50...
  2. Domain IPR001206
    Diacylglycerol kinase, catalytic domain
    1. PS50146 (DAGK)
    2. PF00781 (DAGK_cat)
    3. SM00046 (dagk_c4a_7)
  3. Domain IPR016064
    NAD kinase/diacylglycerol kinase-like domain
    1. SSF111331 (NAD kina...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00660_1
MTSSANYAVIKPNGLEIYSNLETLYSLSTSSKQAAAELDNQSTSCLPICGLSDSSSKPFEEIPYWNILWAQEVPNHNKPL
ANDISSPIELAYMKPESEKKLSPRKIIINVVNTNKPLDDEDKVIRTAPEPIGPDISSMNSKTGLLPQKEEDEEQQTQASA
SSDFVGETADIINNNTNKTQSASPLSSATEAVNTILKAAYKNTKPQKRFLVLINPIGGPGKAKQIYEKQCAPILALAHCK
ATVMVTTHRFHATEIAQSLEHPLENFDAVICCSGDGIPHEVINGFAARPDGWEILKNLPLCQLPCGSGNSMAVSLHGHPS
TSQATLGFIKGIKMPIDLMLMTQGSGADCKKTLTFLSQAFGIIADADLGSENLRWMGGFRFELMVGVRAFRMKKYPCDIY
IKYAHRGTDAVVSHFNENKPSHHHLPSHLHRNSFSKERSHNHKLPQNHHEIQSVNLQDQQPQEPLVPIASSTESLMTPHF
GTVNDPVPEDWEHIDGSSLGLFYSGNMPWVSDGALMFPGVISNDGTFDVLMFDVAGANIVNTLNFYTSIEKGEHVHVDPA
LYSKVVAYRLVPKKDHGYLSIDGESFPHVPFQVEIVPSCACLLSPTGSYAYTGFGK

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003951 NAD+ kinase activity
GO:0016301 kinase activity

Cellular Component

None predicted.