Protein

MCA_00656_1

Length
1,093 amino acids


Gene name: GYP2

Description: GTPase-activating protein Gyp2; in S. cerevisiae involved in recycling of internalized proteins and regulation of Golgi secretory function

Browser: contigA:2054888-2058170+

RNA-seq: read pairs 2499, FPKM 28.2, percentile rank 50.9% (100% = highest expression)

Protein function

Annotation:GYP2GTPase-activating protein Gyp2; in S. cerevisiae involved in recycling of internalized proteins and regulation of Golgi secretory function
KEGG:K19951TBC1D8_9 TBC1 domain family member 8/9
EGGNOG:0PIGFFG08728.1GTPase Activating Protein
SGD closest match:S000003332MDR1GTPase-activating protein GYP2
CGD closest match:CAL0000194959GYP2Gyp2p

Protein alignments

%idAln lengthE-value
MIA_01412_171.83%10650.0MIA_01412_1
A0A0J9X5J6_GEOCN60.37%10800.0Similar to Saccharomyces cerevisiae YGR100W MDR1 Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p OS=Geotrichum candidum GN=BN980_GECA02s04949g PE=4 SV=1
A0A060SYI6_BLAAD63.64%7480.0ARAD1A12650p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A12650g PE=4 SV=1
A0A167DRJ4_9ASCO60.88%7720.0Mdr1p OS=Sugiyamaella lignohabitans GN=MDR1 PE=4 SV=1
UniRef50_A0A167DRJ460.88%7720.0Mdr1p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DRJ4_9ASCO
A0A1E3PKA6_9ASCO47.44%10730.0TBC-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46478 PE=4 SV=1
Q6CG19_YARLI47.39%10720.0YALI0B01628p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B01628g PE=4 SV=1
A0A1D8PMC9_CANAL50.51%7800.0Gyp2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GYP2 PE=4 SV=1
GYP2_YEAST49.64%7010.0GTPase-activating protein GYP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDR1 PE=1 SV=1
A0A1E4TMA9_9ASCO54.39%5920.0Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17757 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2338

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 1000 1093

Detailed signature matches

    1. SM00568 (gram2001c)
    2. PF02893 (GRAM)
    1. PS50086 (TBC_RABGAP)
    2. SSF47923 (Ypt/Rab-G...)
    3. PF00566 (RabGAP-TBC)
    4. SM00164 (tbc_4)
    1. SSF47473 (EF-hand)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_00656_1
MSFFQALKSKASQLSLFDFQPQQASNNEATAQTPSPTITTIYNRKFSPDEVFRHDYHLPPSESLMDQVQAEISIVPADRQ
GQYNSGHIAHPTDEFLIFPGKLYLSESFLIFRSNEDPRDCSFVLSLLTIRKVERLPSQSHIFALSVHIYHGLTVIINFVG
LRSSCEKFCNLLKDNLKSNLPLIKTSKSFLNTFYSEYLVYRVAAAQDKSIQPIPEPPCGLGRLFGYPGDPKKLKDKSKLR
LWYELFKNSGRNISVIRQKSFFKLIRVGLPNKLRGEIWELTCGSVYLRMQNQRLYKSLLEEYKGRNSIAIEEIEKDLNRS
LPEYPAYQNEEGIGRLRRVLTVYSWKNPDVGYCQAMNIVAAALLIYMSEEQAFWCLSLVCDSMLPGYYSKTMYGTLLDQR
VFEELVKRTMPILSDHIIKNDIQLSVVSLPWFLSLFINSMPLVYSFRIMDIFFMEGPKTLFQVALAILRLNGEELLDATD
DGVFISILKDYFSTLSDSAHPESTNPKLRQVTRFQELMITAFKEFSGVTEPMINEYRRKYESKILDDIEVFAKRTQLRNL
SKPRNLTMDQLGIIYDRFYAAIQDTRLGLGATRTDMTLDAFVIFMAGIVDWMDPRYLPEYHSDMSISEKISLIRHQEPND
FVYRLFNRWDSQMLGVLTLQDVVNGLDSLVNPDLMASMTYFFDLYDDEGNGSVDREGILKMSEGFLFLTKPFRESASPIL
DSSSVHLLQANQQAIEKAKSHNEWVKKERESIERNQKRRGSRATHEDQQSVNEDNNVLIDVNSDGESISKKSMESTRKET
DDRASIKSSATAATTNEEPQELPEFVEVPAPLDVTNLQHEQSVRYLSAVSSFINRAFEYATPEPDGSHNSSIKDGKEGGE
KAEDNLDSKLEKMTLKSPSAVSFNVALNPESPLYMSLATFRMVVLADETLETLFSCQLQASVQLTPEGTGLYGSSNDGRG
LAAFGIHGPSGVRSAAMLIAGQGIGGGRAAAATLRSVFDGIVTDVRKRVDEGVSAIVPPSAEDDKEEDDVVAGVGNIKKS
DREVLEEADDQTPTNDDNDITKADDDEKKKKKTEEKPSSSNESIKSEEKKSED

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.