Protein

MCA_00637_1

Length
887 amino acids


Gene name: NPR1A

Description: Putative serine/threonine protein kinase; putative homologie of S. cerevisiae Npr1

Browser: contigA:1982003-1984770-

RNA-seq: read pairs 1939, FPKM 27.0, percentile rank 49.7% (100% = highest expression)

Protein function

Annotation:NPR1APutative serine/threonine protein kinase; putative homologie of S. cerevisiae Npr1
EGGNOG:0PGRBHRK1HAL protein kinase
SGD closest match:S000005127NPR1Nitrogen permease reactivator protein
CGD closest match:CAL0000199299NPR1Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_01323_163.82%5860.0MIA_01323_1
A0A0J9XCU3_GEOCN64.09%4401e-171Similar to Saccharomyces cerevisiae YNL183C NPR1 Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation OS=Geotrichum candidum GN=BN980_GECA10s00934g PE=4 SV=1
UniRef50_A0A0J9XCU364.09%4403e-168Similar to Saccharomyces cerevisiae YNL183C NPR1 Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCU3_GEOCN
A0A167CB51_9ASCO59.68%3774e-141Serine/threonine protein kinase NPR1 OS=Sugiyamaella lignohabitans GN=NPR1 PE=4 SV=1
A0A060TB10_BLAAD61.84%3802e-138ARAD1D24288p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D24288g PE=4 SV=1
Q6CHC6_YARLI59.09%3741e-131YALI0A10230p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A10230g PE=4 SV=1
A0A1E3PFE0_9ASCO57.02%3565e-133Pkinase-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_13686 PE=3 SV=1
A0A1D8PDY7_CANAL50.82%3644e-112Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NPR1 PE=4 SV=1
NPR1_YEAST51.31%3438e-111Nitrogen permease reactivator protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPR1 PE=1 SV=2
A0A1E4TB75_9ASCO45.65%4258e-108Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_53340 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1497

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 887

Detailed signature matches

    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
    1. PS00107 (PROTEIN_KI...)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd13994 (STKc_HAL4_...)
  2. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd13994
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MCA_00637_1
MSSLTENYNKVQINGSANSSTSTLSRMLDSHQSPYTRTTLSQQIASTGSTSMPNTKSNTDQGASPNIQPESYPPVPITHA
VTTDSTDAPTLSRGTSLNPNVSCRKSFSNPSNSISRSSSFSPATSLSSKTSYNNQNLLQPQVSPSITGKTTSSATQTIRD
STDDSKANPTITITTEHQVINDLLPQTEPTQFTEYTTTCSSSEASSIISLKKGFQIGGNTSGEDDSETSSLQSDSGNSGY
HSDTENNSDLDTQKFNQLHINENHESVKNDNDTHVFEANKRLPTGYETSSPTNATAPFSPTAAPSIPIPVAVNHDSAYRS
SVPSSTFSSDRKSLASPTSFTHAADYLASSPNVRDEHPVPFTGNPSSYSSVSSGGFSPRPGSVPNSPSVGPVGNSPAPIK
PPHKVHSTLSLFKGKNKNRNRGNSTSSSTSITHSSSQSSTNTNGSLRTPHTSMADLKRFFQKPWKSNAVNFSDPANIPQL
RSPFAQQGADSPKSRGDSPPSSSSSSTFSKRQTEAKKSLSKTYGKLGKALGEGAGGNVRLVTGKNGRIYAVKEFRQKATH
ESARDYSKKVTGEYCIGLTLKHPNIIETVDIIYETDKIYQVMEYCEYDLFAIVMSGKMSREEVYCDFKQMINGIKYMHES
GLAHRDLKLDNCVINSQGIVKIIDFGSAVVFRYPETEKIHEAVGIVGSDPYLAPEVISNLKYDPRPVDVWSAAIVFCCML
MRKFPWKSPRMSDNSFKQFANGMEAMKKEDAEESRNQQLMKEGLTAGTRQVTLPSGAPASTNLTTSSATEHFTYSYTASA
PQRLLKSLPVETHHLILRMLDTDPETRFSIFDVWNEPWFSTVPFCTVVNDNVVAAPGHTHTTVSFDEAHIATLEKKNKKK
KEKEKLW

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.