Protein

MCA_00622_1

Length
401 amino acids

Gene name: TFA1

Description: Transcription initiation factor IIE subunit alpha

Browser: contigA:1906787-1908198+

RNA-seq: read pairs 759, FPKM 23.3, percentile rank 45.6% (100% = highest expression)

Protein function

Annotation:TFA1Transcription initiation factor IIE subunit alpha
KEGG:K03136TFIIE1 transcription initiation factor TFIIE subunit alpha
EGGNOG:0PI31PGUG_03608transcription initiation factor
SGD closest match:S000001511TFA1Transcription initiation factor IIE subunit alpha
CGD closest match:CAL0000198769TFA1Transcription factor TFIIE subunit

Protein alignments

%idAln lengthE-value
MIA_01318_153.24%3551e-110MIA_01318_1
A0A0J9XJR1_GEOCN49.13%2878e-92Similar to Saccharomyces cerevisiae YKL028W TFA1 TFIIE large subunit OS=Geotrichum candidum GN=BN980_GECA24s01066g PE=4 SV=1
UniRef50_A0A0J9XJR149.13%2872e-88Similar to Saccharomyces cerevisiae YKL028W TFA1 TFIIE large subunit n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJR1_GEOCN
A0A060T761_BLAAD45.08%2953e-86ARAD1C18458p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18458g PE=4 SV=1
A0A167C3T4_9ASCO40.83%3381e-80Tfa1p OS=Sugiyamaella lignohabitans GN=TFA1 PE=4 SV=1
A0A1E3PGW8_9ASCO46.18%2884e-76Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52313 PE=4 SV=1
A0A1E4TK45_9ASCO40.49%2841e-67Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_696 PE=4 SV=1
Q6C0A8_YARLI41.52%2893e-65YALI0F26367p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26367g PE=4 SV=1
T2EA_YEAST38.41%3021e-62Transcription initiation factor IIE subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TFA1 PE=1 SV=1
Q5APB4_CANAL38.52%2831e-62Transcription factor TFIIE subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TFA1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4573
Predicted cleavage: 11

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 401

Detailed signature matches

  1. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
  2. Domain IPR024550
    TFIIEalpha/SarR/Rpc3 HTH domain
    1. PF02002 (TFIIE_alpha)
  3. Domain IPR017919
    Transcription factor TFE/TFIIEalpha HTH domain
    1. PS51344 (HTH_TFE_IIE)
  4. Domain IPR002853
    Transcription initiation factor IIE subunit alpha, N-terminal
    1. SM00531 (tfiie3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.20.25.10
  3. SSF57783 (Zinc beta...)
  4. mobidb-lite (disord...)

Protein sequence

>MCA_00622_1
MDLVNNLIRAVTRRFYDLRYVLVMDALLIHKVLSEDNMAQLLEIQRKDIRALCNKLREEHLIKIHKEEGTNTFRPTSKSF
YYIHYTEAVDAIKWKVHQTVKSIESNMSAQAQTQGYICSQCKTRFNTLDAMSVTDPETGMFLCLVCDGLLVEDDTSEETR
ANQAKKARLMQQLHTILDTLKKIDDAVIPENTYESSLSEAIPPPVKAQSGAYPNQGGNGSNGNNQRYSNSYSANLTSTTQ
LQVNITSKSETHALEQKKIEEKNRVAAANALPAWHLESTVGKTMYTDSPDDSANAAEDANNNNADNTLASAENSGSQVNA
STSNEQQDSSDISAYFAKLAASREQDEDEEEEEDDDDDEDAEFEDVLATTNTEKKTENNDGDDDDDDDDDDDDSEEFEDI
A

GO term prediction

Biological Process

GO:0006367 transcription initiation from RNA polymerase II promoter

Molecular Function

GO:0043565 sequence-specific DNA binding

Cellular Component

None predicted.