MCA_00615_1
Gene name: ALA1
Description: Alanine--tRNA ligase
Browser: contigA:1886705-1889782-
RNA-seq: read pairs 7462, FPKM 95.9, percentile rank 78.0% (100% = highest expression)
Protein function
Annotation: | ALA1 | Alanine--tRNA ligase | |
---|---|---|---|
KEGG: | K01872 | AARS | alanyl-tRNA synthetase [EC:6.1.1.7] |
EGGNOG: | 0PHII | ALA1 | alanyl-tRNA synthetase |
SGD closest match: | S000005862 | ALA1 | Alanine--tRNA ligase, mitochondrial |
CGD closest match: | CAL0000182169 | ALA1 | Alanine--tRNA ligase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_01382_1 | 84.25% | 959 | 0.0 | MIA_01382_1 |
S4SV98_GEOCN | 76.72% | 962 | 0.0 | Alanyl-tRNA synthetase (Fragment) OS=Geotrichum candidum GN=Ala1 PE=3 SV=1 |
Q6CFS9_YARLI | 73.87% | 953 | 0.0 | Alanine--tRNA ligase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ALA1 PE=3 SV=1 |
A0A060T6K1_BLAAD | 72.11% | 961 | 0.0 | Alanine--tRNA ligase OS=Blastobotrys adeninivorans GN=ALA1 PE=3 SV=1 |
SYA_CANAL | 68.05% | 964 | 0.0 | Alanine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ALA1 PE=1 SV=1 |
A0A161HI30_9ASCO | 73.74% | 914 | 0.0 | Alanine--tRNA ligase OS=Sugiyamaella lignohabitans GN=ALA1 PE=3 SV=1 |
UniRef50_A0A099P4F1 | 69.51% | 951 | 0.0 | Alanine--tRNA ligase n=2 Tax=Pichia kudriavzevii TaxID=4909 RepID=A0A099P4F1_PICKU |
A0A1E3PFM0_9ASCO | 70.37% | 908 | 0.0 | Alanine--tRNA ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=ALA1 PE=3 SV=1 |
SYA_YEAST | 65.90% | 956 | 0.0 | Alanine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ALA1 PE=1 SV=3 |
A0A1E4TCY2_9ASCO | 67.08% | 963 | 0.0 | Alanine--tRNA ligase OS=Tortispora caseinolytica NRRL Y-17796 GN=ALA1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0699
Protein family membership
- Alanine-tRNA ligase, class IIc (IPR002318)
- Alanine-tRNA ligase, eukaryota/bacteria (IPR023033)
Domains and repeats
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Domain
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Domain
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Domain
Detailed signature matches
Residue annotation
-
motif 1 cd00673
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active site cd00673
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motif 2 cd00673
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motif 3 cd00673
Protein sequence
>MCA_00615_1 MSTSQLTPENWPATKVRDTFLDFFKSKEHTFVPSSSVIPYDDPTLLFANAGMNQYKPIFLGTVDPSSPLSKISRAANSQK CIRAGGKHNDLEDVGKDSYHHTFFEMLGNWSFGDYFKKEAISWAWELLTKVYGLDPQRLYVTYFGGDEKQGLEPDLEAKQ IWADMGVPEDHILPGSLKDNFWEMGEQGPCGPCSEIHYDRIGGRNAAHLVNMDDPNVLEVWNIVFIQYNREANGELRVLP AQHIDTGMGFERLVSVLQDKLSNYDTDVFTPIFDKIQELTNARPYTGKFGKEDADGIDTAYRVVADHVRTLTFAIADGGY PNNEGRGYVLRRILRRGARYVRKKFDVPIGNFFSRLAPTLIDQVSHIFPELTRDPETIFEILNEEEQSFSRTLDRGEKLF EQYAETAKKNGEKKLNGKDVWRLYDTYGFPVDLTTLMAEEAGLEIDEAEFEKARLESKEASKGGKKSAGKELLKLDVHSL ASLEQNDKVPRTDDHYKYLPDDIEATVTAIYADNKFVDSTKDISPESQLGLLLDKTNFYAEQGGQEYDTGKIVIDGESEF EVENVQTYAGYVLHTGYLKYGDLKVGDKVVAGFDNLRRWPIRNNHTGTHILNFALKEVLGDGVDQKGSLVAPEKLRFDFS HKAALSLKEVEEVENISNKCIEKNLPVYAKDVPLSEATKIAGVRAVFGETYPDPVRVVSVGVPVEDLIAKPENPEWEKYS VEFCGGTHVAKTSDIKELVIIEESGIAKGIRRIVAVTGTTAYDVQKLAKAFDEKLDALESLPSGAEKENRSKNLGVELKK LSVAVVSKAKLNEKYTKIQKKISDESKARQKAEGKKALSTVTEYFEKNADAPYLVLSVPEISANSKALNEAVNHIKAKQP EKSVYLFAGEDGKVAHVCYIGAPAVEKGVSAQELGSIATKFVGGRSGGKGPTVQGAGTDNTKIPDAVSEISKLFKEKLSI
GO term prediction
Biological Process
GO:0006419 alanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004813 alanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
Cellular Component
GO:0005737 cytoplasm